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The map label for this gene is kdpA

Identifier: 170746658

GI number: 170746658

Start: 218099

End: 219814

Strand: Reverse

Name: kdpA

Synonym: Mrad2831_0209

Alternate gene names: 170746658

Gene position: 219814-218099 (Counterclockwise)

Preceding gene: 170746659

Following gene: 170746657

Centisome position: 3.62

GC content: 68.3

Gene sequence:

>1716_bases
ATGACCCTCAACGGCTGGATCCAGATCGCGCTCTACGGCGCGATCGTTCTGGCGCTCGTGAAGCCCCTCGGGTCGTACAT
GACCCGCGTCTTCACCGGAGAGCGCACCTTCCTCTCGCCCGTGCTCGGACCGATCGAGCGCGGTCTCTACCGTGTGTCCG
GCATCGATGACCGCCAGGAGCAGCACTGGCTGGCCTACACGGGTGCGGTCATCCTGTTCCACGTGCTGGGCTTCGCGGTC
CTCTACGCGATCCTGCGGCTGCAGGCGGTGCTGCCGCTGAACCCGGCCGACCAGACCGCGGTGGCGCCGGACCTCGCCTT
CAACACGTCGACCAGCTTCATCACCAACACGAACTGGCAGTCCTACGGCGGCGAGACCACGCTCTCGTACCTGTCCCAGA
TGCTGGGTCTGACGCACCAGAACTTCCTGTCGGCGGCGACCGGCATCGCGGTGGCGGTGGCGCTGATCCGCGGATTCGCG
CGCGCGTCCTCCGGCACGATCGGCTCGTTCTGGGTCGATGTGACCCGCGCCACCCTCTACGTCCTCCTGCCGATCTGCGT
GCCCTACACGCTGTTCCTGGTCTGGCAGGGCATACCTCAGACGCTCGGCGCCTACGCCGACGCCACGACGCTGGAAGGCG
CCAAGCAGACCATCGCGCTCGGACCGGTGGCGAGCCAGGTGGCGATCAAGATGCTCGGCACCAACGGTGGCGGCTTCTTC
AACGCCAACGCCGCGCACCCGTTCGAGAATCCGACCGCGCTGTCGAACCTCGTCCAGATGGTCTCGATCTTCGCGATCGG
CGCCGCCCTCACCAACGTCTTCGGCCGCATGGTCGGCGACGAGCGGCAGGGCTGGGCCATCCTCGGCGCCATGGGGATCC
TGTTCCTCGCGGGCGTCCTCGTCACCTACTGGGCCGAGGCCCACGGAAGCTCCGTCCTGAACAGCTTCGGGCTGACCGGC
GGCAACATGGAGGGCAAGGAGACCCGCTTCGGCATCGCCGCCTCGGCGCTGTTCGCGGTGATCACCACGGCGGCCTCCTG
CGGTGCCGTCAACGCCATGCACGACTCGTTCACGGCGCTCGGCGGCCTGATCCCGCTGCTCAACATGCAACTCGGCGAGA
TCATCATCGGCGGCGTCGGCGCCGGCCTCTACGGCATGCTGATCTTCGTGATCGTGGCGATCTTCGTGGCGGGCCTGATG
GTCGGCCGAACCCCCGAGTACCTCGGCAAGAAGATCGAGGCGAAGGAGGTGAAGATGGCCATGCTCGGCATCCTCTGCCT
GCCGCTGATGATGCTGGGCTTCACGGCGCTAGCGACGGTGGTGCCGGCGGGCCTCGCCGGCCCGGCCAATGCCGGCCCGC
ACGGCTTCACCGAGATCCTCTACGCCTACACGTCGGCGGCGGCCAACAACGGCTCGGCCTTCGGCGGGCTGACGGCCAAC
ACGCTGTTCTACAACAGCACGCTCGCCATCGGCATGCTGGTCGGCCGGTTCTTCGTGAAGATCCCCGTGCTCGCCATCGC
GGGCTCGCTCGCCGCCAAGAAGACGGTCCCGGCCTCGGCAGGCACCTTCCCGACCCACGGCGGCCTGTTCGTCGGGCTGC
TCGTCGGGGTGATCCTGATCATCGGCGGCCTGACCTTCTTCCCCTCGCTGGCGCTGGGCCCCGTGGTCGAGCACCTCGCG
GGCGCCGCCGGCCAGACCTTCGCGACGGGGGGCTGA

Upstream 100 bases:

>100_bases
CCTCGCCCTCGGCGCCTGCGTGACCGCCGGCCTCCTCGTCTACCTCACCTACGCCCTCGTCCGCCCCGAGCGGTTCTGAG
CGGCCCGCAGGATCTCCCCC

Downstream 100 bases:

>100_bases
GATGCCGCGCGCCCTCCCCGCCCGGCGCGTCGCGCGCCACCACCTCGTGCTGCACCGGCAGCCGCATCGCGCCGGCCGTG
CCGGAGCCCCGCCCCCGCGG

Product: potassium-transporting ATPase A

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MTLNGWIQIALYGAIVLALVKPLGSYMTRVFTGERTFLSPVLGPIERGLYRVSGIDDRQEQHWLAYTGAVILFHVLGFAV
LYAILRLQAVLPLNPADQTAVAPDLAFNTSTSFITNTNWQSYGGETTLSYLSQMLGLTHQNFLSAATGIAVAVALIRGFA
RASSGTIGSFWVDVTRATLYVLLPICVPYTLFLVWQGIPQTLGAYADATTLEGAKQTIALGPVASQVAIKMLGTNGGGFF
NANAAHPFENPTALSNLVQMVSIFAIGAALTNVFGRMVGDERQGWAILGAMGILFLAGVLVTYWAEAHGSSVLNSFGLTG
GNMEGKETRFGIAASALFAVITTAASCGAVNAMHDSFTALGGLIPLLNMQLGEIIIGGVGAGLYGMLIFVIVAIFVAGLM
VGRTPEYLGKKIEAKEVKMAMLGILCLPLMMLGFTALATVVPAGLAGPANAGPHGFTEILYAYTSAAANNGSAFGGLTAN
TLFYNSTLAIGMLVGRFFVKIPVLAIAGSLAAKKTVPASAGTFPTHGGLFVGLLVGVILIIGGLTFFPSLALGPVVEHLA
GAAGQTFATGG

Sequences:

>Translated_571_residues
MTLNGWIQIALYGAIVLALVKPLGSYMTRVFTGERTFLSPVLGPIERGLYRVSGIDDRQEQHWLAYTGAVILFHVLGFAV
LYAILRLQAVLPLNPADQTAVAPDLAFNTSTSFITNTNWQSYGGETTLSYLSQMLGLTHQNFLSAATGIAVAVALIRGFA
RASSGTIGSFWVDVTRATLYVLLPICVPYTLFLVWQGIPQTLGAYADATTLEGAKQTIALGPVASQVAIKMLGTNGGGFF
NANAAHPFENPTALSNLVQMVSIFAIGAALTNVFGRMVGDERQGWAILGAMGILFLAGVLVTYWAEAHGSSVLNSFGLTG
GNMEGKETRFGIAASALFAVITTAASCGAVNAMHDSFTALGGLIPLLNMQLGEIIIGGVGAGLYGMLIFVIVAIFVAGLM
VGRTPEYLGKKIEAKEVKMAMLGILCLPLMMLGFTALATVVPAGLAGPANAGPHGFTEILYAYTSAAANNGSAFGGLTAN
TLFYNSTLAIGMLVGRFFVKIPVLAIAGSLAAKKTVPASAGTFPTHGGLFVGLLVGVILIIGGLTFFPSLALGPVVEHLA
GAAGQTFATGG
>Mature_570_residues
TLNGWIQIALYGAIVLALVKPLGSYMTRVFTGERTFLSPVLGPIERGLYRVSGIDDRQEQHWLAYTGAVILFHVLGFAVL
YAILRLQAVLPLNPADQTAVAPDLAFNTSTSFITNTNWQSYGGETTLSYLSQMLGLTHQNFLSAATGIAVAVALIRGFAR
ASSGTIGSFWVDVTRATLYVLLPICVPYTLFLVWQGIPQTLGAYADATTLEGAKQTIALGPVASQVAIKMLGTNGGGFFN
ANAAHPFENPTALSNLVQMVSIFAIGAALTNVFGRMVGDERQGWAILGAMGILFLAGVLVTYWAEAHGSSVLNSFGLTGG
NMEGKETRFGIAASALFAVITTAASCGAVNAMHDSFTALGGLIPLLNMQLGEIIIGGVGAGLYGMLIFVIVAIFVAGLMV
GRTPEYLGKKIEAKEVKMAMLGILCLPLMMLGFTALATVVPAGLAGPANAGPHGFTEILYAYTSAAANNGSAFGGLTANT
LFYNSTLAIGMLVGRFFVKIPVLAIAGSLAAKKTVPASAGTFPTHGGLFVGLLVGVILIIGGLTFFPSLALGPVVEHLAG
AAGQTFATGG

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

COG id: COG2060

COG function: function code P; K+-transporting ATPase, A chain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdpA family

Homologues:

Organism=Escherichia coli, GI1786915, Length=563, Percent_Identity=55.7726465364121, Blast_Score=603, Evalue=1e-173,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATKA_METRJ (B1M7D7)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001752918.1
- GeneID:   6136051
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_0209
- HOGENOM:   HBG291815
- OMA:   MSYLTQM
- ProtClustDB:   PRK05482
- HAMAP:   MF_00275
- InterPro:   IPR004623
- PIRSF:   PIRSF001294
- TIGRFAMs:   TIGR00680

Pfam domain/function: PF03814 KdpA

EC number: =3.6.3.12

Molecular weight: Translated: 59274; Mature: 59143

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x158646b4)-; HASH(0x15959258)-; HASH(0x1582b4fc)-; HASH(0x150695c0)-; HASH(0x14d8c5cc)-; HASH(0x153aef8c)-; HASH(0x15ee6fb4)-; HASH(0x15fe6e08)-; HASH(0x15a38544)-; HASH(0x159081e0)-; HASH(0x146b2074)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNGWIQIALYGAIVLALVKPLGSYMTRVFTGERTFLSPVLGPIERGLYRVSGIDDRQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCHHH
QHWLAYTGAVILFHVLGFAVLYAILRLQAVLPLNPADQTAVAPDLAFNTSTSFITNTNWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCH
SYGGETTLSYLSQMLGLTHQNFLSAATGIAVAVALIRGFARASSGTIGSFWVDVTRATLY
HCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VLLPICVPYTLFLVWQGIPQTLGAYADATTLEGAKQTIALGPVASQVAIKMLGTNGGGFF
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCHHHEEECCHHHHHHHHHEECCCCCEE
NANAAHPFENPTALSNLVQMVSIFAIGAALTNVFGRMVGDERQGWAILGAMGILFLAGVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VTYWAEAHGSSVLNSFGLTGGNMEGKETRFGIAASALFAVITTAASCGAVNAMHDSFTAL
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GGLIPLLNMQLGEIIIGGVGAGLYGMLIFVIVAIFVAGLMVGRTPEYLGKKIEAKEVKMA
HHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHH
MLGILCLPLMMLGFTALATVVPAGLAGPANAGPHGFTEILYAYTSAAANNGSAFGGLTAN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
TLFYNSTLAIGMLVGRFFVKIPVLAIAGSLAAKKTVPASAGTFPTHGGLFVGLLVGVILI
HEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IGGLTFFPSLALGPVVEHLAGAAGQTFATGG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure 
TLNGWIQIALYGAIVLALVKPLGSYMTRVFTGERTFLSPVLGPIERGLYRVSGIDDRQE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCHHH
QHWLAYTGAVILFHVLGFAVLYAILRLQAVLPLNPADQTAVAPDLAFNTSTSFITNTNWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCH
SYGGETTLSYLSQMLGLTHQNFLSAATGIAVAVALIRGFARASSGTIGSFWVDVTRATLY
HCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VLLPICVPYTLFLVWQGIPQTLGAYADATTLEGAKQTIALGPVASQVAIKMLGTNGGGFF
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCHHHEEECCHHHHHHHHHEECCCCCEE
NANAAHPFENPTALSNLVQMVSIFAIGAALTNVFGRMVGDERQGWAILGAMGILFLAGVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VTYWAEAHGSSVLNSFGLTGGNMEGKETRFGIAASALFAVITTAASCGAVNAMHDSFTAL
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GGLIPLLNMQLGEIIIGGVGAGLYGMLIFVIVAIFVAGLMVGRTPEYLGKKIEAKEVKMA
HHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHH
MLGILCLPLMMLGFTALATVVPAGLAGPANAGPHGFTEILYAYTSAAANNGSAFGGLTAN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
TLFYNSTLAIGMLVGRFFVKIPVLAIAGSLAAKKTVPASAGTFPTHGGLFVGLLVGVILI
HEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IGGLTFFPSLALGPVVEHLAGAAGQTFATGG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA