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The map label for this gene is lsrC [H]

Identifier: 170681527

GI number: 170681527

Start: 1645575

End: 1646603

Strand: Reverse

Name: lsrC [H]

Synonym: EcSMS35_1658

Alternate gene names: 170681527

Gene position: 1646603-1645575 (Counterclockwise)

Preceding gene: 170679722

Following gene: 170680972

Centisome position: 32.49

GC content: 53.84

Gene sequence:

>1029_bases
ATGCTGAAATTTATTCAGAACAACCGTGAAATCACGGCACTGCTGGCGGTGGTGCTGCTGTTTGTATTACCCGGTTTTCT
CGACCGTCAGTATTTAAGTGTGCAAACGCTGACCATGGTTTATAGCAGCGCGCAAATCCTGATCCTGCTGGCAATGGGCG
CGACGCTGGTAATGCTTACGCGCAATATTGATGTTTCAGTGGGTTCGATTACCGGAATGTGCGCGGTGCTGTTGGGGATG
TTACTGAACGCGGGGTATTCACTACCTGTTGCTTGTGTCGCGACTTTACTGCTTGGTTTGCTCGCGGGATTTTTCAACGG
TGTCCTGGTCGCGTGGCTAAAGATCCCTGCCATTGTTGCCACGCTCGGTACATTAGGGTTGTACAGAGGCATCATGTTGC
TGTGGACTGGCGGTAAATGGATTGAGGGATTACCCGCCGAACTGAAACAACTCTCCGCCCCGCTGCTGTTTGGCGTTTCC
GCGATTGGTTGGTTGACGATAATTCTGGTGGCATTTATGGCCTGGCTGCTGGCAAAGACGGCGTTTGGACGCAGTTTTTA
TGTCACGGGCGATAATTTACAGGGCGCTCGTCAACTGGGCGTTCGTACGGAAGCCATTCGCATTGTGGCATTTTCGTTGA
ACGGCTGCATGGCGGCACTGGCGGGAATTGTGTTTGCTTCGCAGATTGGTTTTATCCCCAACCAGACCGGTACCGGGCTG
GAGATGAAAGCAATTGCAGCCTGCGTTCTGGGCGGCATTAGTTTGCTCGGCGGTTCCGGCGCGATCATCGGTGCGGTACT
CGGCGCATGGTTCCTGACGCAGATCGATAGTGTACTGGTGCTGTTGCGCATTCCGGCATGGTGGAATGATTTTATCGCGG
GCATGGTTCTGCTGGCGGTGCTGGTGTTTGATGGACGCCTGCGTTGTGCGCTGGAACGTAATCTGCGGCGGCAAAAATAT
GCCCGCTTTATGATGCCACCGCCACCCGTTAAACCCGCTTCGTCAGGTAAAAAACGGGAGGCCGCGTAA

Upstream 100 bases:

>100_bases
ATCAGGGCGAAATTGCCCACTCTGCACTGACCGGGCGCGATATTAATGTCGAGACCATTATGCGCGTTGCCTTCGGCGAT
AGTCAGCGTCAGGAGGCGTC

Downstream 100 bases:

>100_bases
TGCGTATTCGCTACGGTTGGGAACTGGCTCTTGCCGCACTGCTCGTTATTGAGATTGTTGCATTTGGTGCAATTAACCCG
CGGATGTTAGATCTCAATAT

Product: autoinducer-2 ABC transporter permease LsrC

Products: NA

Alternate protein names: AI-2 import system permease protein lsrC [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGM
LLNAGYSLPVACVATLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVS
AIGWLTIILVAFMAWLLAKTAFGRSFYVTGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGMVLLAVLVFDGRLRCALERNLRRQKY
ARFMMPPPPVKPASSGKKREAA

Sequences:

>Translated_342_residues
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGM
LLNAGYSLPVACVATLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVS
AIGWLTIILVAFMAWLLAKTAFGRSFYVTGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGMVLLAVLVFDGRLRCALERNLRRQKY
ARFMMPPPPVKPASSGKKREAA
>Mature_342_residues
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGM
LLNAGYSLPVACVATLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVS
AIGWLTIILVAFMAWLLAKTAFGRSFYVTGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGMVLLAVLVFDGRLRCALERNLRRQKY
ARFMMPPPPVKPASSGKKREAA

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787793, Length=342, Percent_Identity=98.5380116959064, Blast_Score=659, Evalue=0.0,
Organism=Escherichia coli, GI1789992, Length=362, Percent_Identity=30.3867403314917, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI145693152, Length=267, Percent_Identity=34.0823970037453, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790191, Length=308, Percent_Identity=31.1688311688312, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788896, Length=303, Percent_Identity=30.3630363036304, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790524, Length=277, Percent_Identity=26.7148014440433, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI145693214, Length=283, Percent_Identity=33.9222614840989, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082395, Length=288, Percent_Identity=30.5555555555556, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787794, Length=313, Percent_Identity=30.6709265175719, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788471, Length=307, Percent_Identity=29.3159609120521, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 36516; Mature: 36516

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLT
CCCCCCCCCHHHHHHHHHHHHHHCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVATLLLGLLAGFFNGVLVAWLKIPAIVA
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVSAIGWLTIILVAFMAWLLAKT
HHHHHHHHHHHHEEECCCHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGRSFYVTGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
HCCCEEEEECCCCCHHHHHCCHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGMVLLAV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVFDGRLRCALERNLRRQKYARFMMPPPPVKPASSGKKREAA
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLT
CCCCCCCCCHHHHHHHHHHHHHHCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVATLLLGLLAGFFNGVLVAWLKIPAIVA
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVSAIGWLTIILVAFMAWLLAKT
HHHHHHHHHHHHEEECCCHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGRSFYVTGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
HCCCEEEEECCCCCHHHHHCCHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGMVLLAV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVFDGRLRCALERNLRRQKYARFMMPPPPVKPASSGKKREAA
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]