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The map label for this gene is ycjQ [H]

Identifier: 170681445

GI number: 170681445

Start: 1829833

End: 1830885

Strand: Reverse

Name: ycjQ [H]

Synonym: EcSMS35_1809

Alternate gene names: 170681445

Gene position: 1830885-1829833 (Counterclockwise)

Preceding gene: 170682092

Following gene: 170683456

Centisome position: 36.12

GC content: 55.94

Gene sequence:

>1053_bases
ATGAAAAAGTTAGTAGCCACAGCACCGCGCGTTGCTGCGCTGGTTGAGTATGAAGATCGGGCGATTTTAGCCAATGAAGT
GAAGATCCGCGTGCGTTTCGGCGCACCGAAACACGGAACGGAAGTGGTCGACTTCCGCGCCGCCAGCCCGTTTATCGATG
AAGACTTTAACGGCGAGTGGCAGATGTTCACCCCGCGTCCCGCAGATGCGCCGCGCGGCATTGAGTTTGGCAAATTCCAG
CTTGGCAACATGGTGGTTGGCGACATTATCGAGTGCGGCAGCGACGTTACCGACTACGCGGTGGGCGACAGCGTATGCGG
CTACGGCCCGCTCTCCGAGACGGTCATCATTAACGCAGTGAATAACTACAAGCTGCGCAAAATGCCGCAAGGCAGCTCCT
GGAAAAACGCCGTCTGTTACGACCCGGCGCAGTTTGCCATGAGCGGCGTGCGCGATGCCAACGTACGCGTAGGGGATTTT
GTCGTGGTGGTAGGGCTTGGCGCGATCGGTCAAATTGCCATCCAACTGGCGAAACGCGCTGGCGCATCGGTGGTAATTGG
CGTCGATCCTATCGCCCATCGCTGTGAGATTGCCCGTCGCCACGGTGCTGATTTCTGCCTTAACCCCATTGGCACTGACG
TAGGCAAAGAGATCAAAACGCTGACCGGCAAGCAGGGTGCCGATGTGATTATCGAAACCAGCGGTTACGCCGACGCGCTG
CAATCGGCGCTGCGCGGTCTGTCCTACGGCGGCACCATCTCGTATGTCGCGTTTGCCAAACCATTTGCTGAAGGTTTTAA
CCTCGGACGCGAAGCGCATTTCAATAACGCCAAAATTGTTTTCTCCCGCGCGTGCAGCGAACCGAACCCGGATTATCCGC
GCTGGAGCCGTAAGCGTATTGAAGAAACCTGCTGGGAACTGCTGATGAACGGTTATCTCAATTGCGAAGATTTAATCGAC
CCGGTAGTGACCTTTGCCAACAGCCCGGAAAGCTACATGCAGTATGTCGATCAGCATCCGGAACAGAGCATCAAAATGGG
CGTTACGTTTTAA

Upstream 100 bases:

>100_bases
GGTGATTATGTATGCGCTTTCGGAACGTTTTATTAAGAGTGGTTTGACCGCCGGTGGCGTGAAGGGCTAAAGCGGCCAGT
TTCTTTACAAGGAGTTTTAC

Downstream 100 bases:

>100_bases
TTCAAAGGAATGAAAAAATGAAAATAGGCACACAGAATCAGGCATTCTTTCCGGAAAATATTCTGGAGAAATTTCGTTAT
ATCAAAGAGATGGGCTTCGA

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQ
LGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCEIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
QSALRGLSYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLID
PVVTFANSPESYMQYVDQHPEQSIKMGVTF

Sequences:

>Translated_350_residues
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQ
LGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCEIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
QSALRGLSYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLID
PVVTFANSPESYMQYVDQHPEQSIKMGVTF
>Mature_350_residues
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQ
LGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCEIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
QSALRGLSYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLID
PVVTFANSPESYMQYVDQHPEQSIKMGVTF

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787572, Length=350, Percent_Identity=99.4285714285714, Blast_Score=722, Evalue=0.0,
Organism=Escherichia coli, GI1790045, Length=208, Percent_Identity=26.4423076923077, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=154, Percent_Identity=32.4675324675325, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=138, Percent_Identity=32.6086956521739, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322619, Length=216, Percent_Identity=27.3148148148148, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=216, Percent_Identity=27.3148148148148, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38247; Mature: 38247

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEW
CCCCHHCCCHHHEEEEECCCEEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCE
QMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETVIINAV
EEECCCCCCCCCCCCCCCEEECCCHHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEEEEEC
NNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDFVVVVGLGAIGQIAIQLAKRA
CCCEEEECCCCCCCCCCEEECHHHHHHHCCCCCCCEECCEEEEEECCHHHHHHHHHHHHC
GASVVIGVDPIAHRCEIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
CCEEEEECCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHH
QSALRGLSYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRI
HHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
EETCWELLMNGYLNCEDLIDPVVTFANSPESYMQYVDQHPEQSIKMGVTF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEW
CCCCHHCCCHHHEEEEECCCEEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCE
QMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETVIINAV
EEECCCCCCCCCCCCCCCEEECCCHHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEEEEEC
NNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDFVVVVGLGAIGQIAIQLAKRA
CCCEEEECCCCCCCCCCEEECHHHHHHHCCCCCCCEECCEEEEEECCHHHHHHHHHHHHC
GASVVIGVDPIAHRCEIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
CCEEEEECCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHH
QSALRGLSYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRI
HHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
EETCWELLMNGYLNCEDLIDPVVTFANSPESYMQYVDQHPEQSIKMGVTF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]