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The map label for this gene is pgl [H]

Identifier: 170077550

GI number: 170077550

Start: 959175

End: 959933

Strand: Reverse

Name: pgl [H]

Synonym: SYNPCC7002_A0928

Alternate gene names: 170077550

Gene position: 959933-959175 (Counterclockwise)

Preceding gene: 170077554

Following gene: 170077549

Centisome position: 31.91

GC content: 55.2

Gene sequence:

>759_bases
ATGACAAAATACCTGGAAATCCTGGATGACAAACCGGAACTCATTAAACGGGCGCTGCGTATTGTCATGGGCCGGATTGA
GGAGGCGATCGCCCGTCGTGGTGTCTGTACCATTGCCCTTGCCGGCGGCAGTACCCCCAAACCTTTATACGAAAAATTAG
CAGAGCAATCCCTCCCCTGGGCGCAACTCCACATTTTCTGGGGAGATGAACGCTATGTACCTGCCGAGCACCCCGATAGT
AATCAACGGATGGCCCGGCTCGCCTGGCTGGATCAGGTGCCGATTCCGGAGGGCAATATTCACCCGATGCCGACCGCAGC
CGCAGACCCCCAGCAAGATGCAGCGGCCTATGACGCAACGTTGAGAAATTTTTTTGGCGATCGCCCCTGGCCCAGTTTCG
ATATTGTGCTGTTGGGCATGGGGGACGATGGTCATACTGCTTCGTTATTTCCCCAAACGGCGGCCCTAACCGTTGGCGAT
CGCCTCATCACCGTTGGCGAGAAACAGGGAGAACCCAGGCTGACCTTTACCGTGCCCCTGATTAATGCCGCCCAGAACAT
TCTTTTCCTAGTCGCTGGGGAAAATAAACAGGAGGCGCTCCAGAAAATTTTCCATAGCGATGCCGATGGGTTTGCCTATC
CCAGTAAATTGATCAACCCAGACCACGGTGTCCTCTGGTGGCTCCTGGATGCTGCTGCTGGCGATCGCCTCGCCCCCGAT
CAAGCAATCTATCAAACGAAATCTCGCCCAGAGCCTTAA

Upstream 100 bases:

>100_bases
TTCATACTTTATGTATCAGTCAATGGGCGTTTATGGGTGTCACCACTAGAATGACGAGTAACGCTATTTTAGGGGGCATG
GTTCGTCCTCTGTAAAGTTT

Downstream 100 bases:

>100_bases
AATAAAACCATTCTTTTCCCTTTGACCACCCACTGTCATGATTAGTTGTCCCAACTGTAACCACCAAAATCCTGACGGCG
CCGTCCAATGCGAAGCCTGT

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTKYLEILDDKPELIKRALRIVMGRIEEAIARRGVCTIALAGGSTPKPLYEKLAEQSLPWAQLHIFWGDERYVPAEHPDS
NQRMARLAWLDQVPIPEGNIHPMPTAAADPQQDAAAYDATLRNFFGDRPWPSFDIVLLGMGDDGHTASLFPQTAALTVGD
RLITVGEKQGEPRLTFTVPLINAAQNILFLVAGENKQEALQKIFHSDADGFAYPSKLINPDHGVLWWLLDAAAGDRLAPD
QAIYQTKSRPEP

Sequences:

>Translated_252_residues
MTKYLEILDDKPELIKRALRIVMGRIEEAIARRGVCTIALAGGSTPKPLYEKLAEQSLPWAQLHIFWGDERYVPAEHPDS
NQRMARLAWLDQVPIPEGNIHPMPTAAADPQQDAAAYDATLRNFFGDRPWPSFDIVLLGMGDDGHTASLFPQTAALTVGD
RLITVGEKQGEPRLTFTVPLINAAQNILFLVAGENKQEALQKIFHSDADGFAYPSKLINPDHGVLWWLLDAAAGDRLAPD
QAIYQTKSRPEP
>Mature_251_residues
TKYLEILDDKPELIKRALRIVMGRIEEAIARRGVCTIALAGGSTPKPLYEKLAEQSLPWAQLHIFWGDERYVPAEHPDSN
QRMARLAWLDQVPIPEGNIHPMPTAAADPQQDAAAYDATLRNFFGDRPWPSFDIVLLGMGDDGHTASLFPQTAALTVGDR
LITVGEKQGEPRLTFTVPLINAAQNILFLVAGENKQEALQKIFHSDADGFAYPSKLINPDHGVLWWLLDAAAGDRLAPDQ
AIYQTKSRPEP

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=227, Percent_Identity=35.2422907488987, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI6912586, Length=230, Percent_Identity=31.304347826087, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115533058, Length=245, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115533060, Length=245, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321957, Length=247, Percent_Identity=28.7449392712551, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6321687, Length=248, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324362, Length=207, Percent_Identity=29.951690821256, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319918, Length=216, Percent_Identity=30.0925925925926, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24641119, Length=234, Percent_Identity=36.7521367521368, Blast_Score=115, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900
- InterPro:   IPR006148 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 27928; Mature: 27797

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYLEILDDKPELIKRALRIVMGRIEEAIARRGVCTIALAGGSTPKPLYEKLAEQSLPW
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCE
AQLHIFWGDERYVPAEHPDSNQRMARLAWLDQVPIPEGNIHPMPTAAADPQQDAAAYDAT
EEEEEEECCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LRNFFGDRPWPSFDIVLLGMGDDGHTASLFPQTAALTVGDRLITVGEKQGEPRLTFTVPL
HHHHCCCCCCCCEEEEEEEECCCCCEEECCCCHHEEEECCEEEEECCCCCCCEEEEEEEC
INAAQNILFLVAGENKQEALQKIFHSDADGFAYPSKLINPDHGVLWWLLDAAAGDRLAPD
HHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCCH
QAIYQTKSRPEP
HHHHHCCCCCCC
>Mature Secondary Structure 
TKYLEILDDKPELIKRALRIVMGRIEEAIARRGVCTIALAGGSTPKPLYEKLAEQSLPW
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCE
AQLHIFWGDERYVPAEHPDSNQRMARLAWLDQVPIPEGNIHPMPTAAADPQQDAAAYDAT
EEEEEEECCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LRNFFGDRPWPSFDIVLLGMGDDGHTASLFPQTAALTVGDRLITVGEKQGEPRLTFTVPL
HHHHCCCCCCCCEEEEEEEECCCCCEEECCCCHHEEEECCEEEEECCCCCCCEEEEEEEC
INAAQNILFLVAGENKQEALQKIFHSDADGFAYPSKLINPDHGVLWWLLDAAAGDRLAPD
HHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCCH
QAIYQTKSRPEP
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]