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The map label for this gene is ndhA

Identifier: 170077548

GI number: 170077548

Start: 957005

End: 958123

Strand: Reverse

Name: ndhA

Synonym: SYNPCC7002_A0926

Alternate gene names: 170077548

Gene position: 958123-957005 (Counterclockwise)

Preceding gene: 170077549

Following gene: 170077547

Centisome position: 31.85

GC content: 50.31

Gene sequence:

>1119_bases
ATGAACTCAGGAATCGATCTTCAAGGTAGTTTTATCGAAACCCTCCAATCCTTTGGGTTGTCCCATGAAATTGCCAAGAC
TATTTGGCTACCCCTACCGTTGTTACTGATGATTATTGGCGCGACAGTGGGTGTTTTAGTCGTGGTGTGGTTAGAGCGAA
AAATTTCAGCGGCAGCCCAACAACGGGTTGGCCCGGAATATGCAGGCCCCCTAGGGGTTTTACAGCCGGTGGCCGATGGT
TTAAAGCTGGTTTTTAAAGAAGATGTGGTCCCCGCTAAAACAGATCCCTGGCTCTTTACCCTCGGGCCTGCTCTCGTGGT
CATTCCGGTCTTTTTGTCCTATCTCATCGTTCCCTTCGGGCAAAACCTGGTGATTACGGATTTGAACGTGGGGATTTTTC
TGTGGATTTCCCTCTCAAGCATCGCTCCCATTGGCCTTTTGATGTCAGGCTACTCTTCTAATAATAAATATGCGTTACTG
GGGGGACTGCGTGCTGCCGCCCAATCAATCAGCTACGAAATTCCCCTGGCCCTGGCTGTATTGGCGATCGCCATGATGTC
CAATAGCCTGAGCACCATTGACATTGTTGAACAACAATCCGGTTACGGCATTTTAGGCTGGAATATTTGGCGACAACCCG
TTGGCTTCCTCATTTTCTGGATTGCGGCCCTCGCCGAATGCGAACGTCTCCCCTTTGACCTCCCTGAAGCAGAAGAAGAA
CTTGTCGCTGGCTATCAAACCGAATATGCCGGGATGAAGTTTGGTCTGTTCTATGTTGGTTCCTACGTCAACCTTGTGCT
CTCGGCCTTGATTGTTTCAATTCTCTACCTAGGCGGTTGGGAGTTTCCCATTCCCCTCGATAAGCTTGCCGGTTGGTTAA
ACGTTGCCCCCAGCACCCCTTGGCTCCAGGTGATCACCGCCTCCTTGGGGATTATTATGACCCTCGTGAAAACCTATGCC
TTGGTCTTTATCGCTGTCCTCCTACGCTGGACTTTACCGCGAGTACGCATTGACCAACTTTTGAACTTTGGCTGGAAGTT
TCTCCTCCCCGTTGCCCTCGTTAATCTATTGCTCACGGCGGCCCTAAAACTTGCTTTCCCCATTGCTTTTGGGGGCTAA

Upstream 100 bases:

>100_bases
CCGGAACAACGATATACTAATTCAGTGATGTCACTTTTGTTGGAAATCCCTGCCTCGATACATTCCCTTAACAATCCATC
GTGCAGGCCAAAGAACCCCT

Downstream 100 bases:

>100_bases
AGCTTCGTCGTTTCTTTCTCCTTCTTTGTTGATCTTCTCACCCTATGTCCTATGTTTAAAATCCTCAAACAAGTCGGTGA
CTATGCCAAGGATGCAGCCC

Product: NADH dehydrogenase subunit H

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I subunit 1; NDH-1 subunit 1; NDH-A

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MNSGIDLQGSFIETLQSFGLSHEIAKTIWLPLPLLLMIIGATVGVLVVVWLERKISAAAQQRVGPEYAGPLGVLQPVADG
LKLVFKEDVVPAKTDPWLFTLGPALVVIPVFLSYLIVPFGQNLVITDLNVGIFLWISLSSIAPIGLLMSGYSSNNKYALL
GGLRAAAQSISYEIPLALAVLAIAMMSNSLSTIDIVEQQSGYGILGWNIWRQPVGFLIFWIAALAECERLPFDLPEAEEE
LVAGYQTEYAGMKFGLFYVGSYVNLVLSALIVSILYLGGWEFPIPLDKLAGWLNVAPSTPWLQVITASLGIIMTLVKTYA
LVFIAVLLRWTLPRVRIDQLLNFGWKFLLPVALVNLLLTAALKLAFPIAFGG

Sequences:

>Translated_372_residues
MNSGIDLQGSFIETLQSFGLSHEIAKTIWLPLPLLLMIIGATVGVLVVVWLERKISAAAQQRVGPEYAGPLGVLQPVADG
LKLVFKEDVVPAKTDPWLFTLGPALVVIPVFLSYLIVPFGQNLVITDLNVGIFLWISLSSIAPIGLLMSGYSSNNKYALL
GGLRAAAQSISYEIPLALAVLAIAMMSNSLSTIDIVEQQSGYGILGWNIWRQPVGFLIFWIAALAECERLPFDLPEAEEE
LVAGYQTEYAGMKFGLFYVGSYVNLVLSALIVSILYLGGWEFPIPLDKLAGWLNVAPSTPWLQVITASLGIIMTLVKTYA
LVFIAVLLRWTLPRVRIDQLLNFGWKFLLPVALVNLLLTAALKLAFPIAFGG
>Mature_372_residues
MNSGIDLQGSFIETLQSFGLSHEIAKTIWLPLPLLLMIIGATVGVLVVVWLERKISAAAQQRVGPEYAGPLGVLQPVADG
LKLVFKEDVVPAKTDPWLFTLGPALVVIPVFLSYLIVPFGQNLVITDLNVGIFLWISLSSIAPIGLLMSGYSSNNKYALL
GGLRAAAQSISYEIPLALAVLAIAMMSNSLSTIDIVEQQSGYGILGWNIWRQPVGFLIFWIAALAECERLPFDLPEAEEE
LVAGYQTEYAGMKFGLFYVGSYVNLVLSALIVSILYLGGWEFPIPLDKLAGWLNVAPSTPWLQVITASLGIIMTLVKTYA
LVFIAVLLRWTLPRVRIDQLLNFGWKFLLPVALVNLLLTAALKLAFPIAFGG

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family

Homologues:

Organism=Homo sapiens, GI251831107, Length=306, Percent_Identity=33.6601307189542, Blast_Score=158, Evalue=8e-39,
Organism=Escherichia coli, GI1788618, Length=341, Percent_Identity=40.7624633431085, Blast_Score=238, Evalue=4e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NU1C_SYNP2 (Q8KX60)

Other databases:

- EMBL:   AF381034
- EMBL:   CP000951
- RefSeq:   YP_001734186.1
- GeneID:   6056857
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A0926
- HOGENOM:   HBG727670
- OMA:   IFWICAL
- ProtClustDB:   PRK06076
- HAMAP:   MF_01350
- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086
- PANTHER:   PTHR11432

Pfam domain/function: PF00146 NADHdh

EC number: 1.6.5.3

Molecular weight: Translated: 40518; Mature: 40518

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00667 COMPLEX1_ND1_1; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b916a20)-; HASH(0x19e4cc98)-; HASH(0x1b8e1818)-; HASH(0x1a67f6cc)-; HASH(0x1b18be9c)-; HASH(0x1acbb290)-; HASH(0x1ba4f628)-; HASH(0x1a257458)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSGIDLQGSFIETLQSFGLSHEIAKTIWLPLPLLLMIIGATVGVLVVVWLERKISAAAQ
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRVGPEYAGPLGVLQPVADGLKLVFKEDVVPAKTDPWLFTLGPALVVIPVFLSYLIVPFG
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCC
QNLVITDLNVGIFLWISLSSIAPIGLLMSGYSSNNKYALLGGLRAAAQSISYEIPLALAV
CCEEEEECCCCEEEEEEHHHHCHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHH
LAIAMMSNSLSTIDIVEQQSGYGILGWNIWRQPVGFLIFWIAALAECERLPFDLPEAEEE
HHHHHHHCCCCHHHHEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LVAGYQTEYAGMKFGLFYVGSYVNLVLSALIVSILYLGGWEFPIPLDKLAGWLNVAPSTP
HHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCH
WLQVITASLGIIMTLVKTYALVFIAVLLRWTLPRVRIDQLLNFGWKFLLPVALVNLLLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALKLAFPIAFGG
HHHHHHHHCCCH
>Mature Secondary Structure
MNSGIDLQGSFIETLQSFGLSHEIAKTIWLPLPLLLMIIGATVGVLVVVWLERKISAAAQ
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRVGPEYAGPLGVLQPVADGLKLVFKEDVVPAKTDPWLFTLGPALVVIPVFLSYLIVPFG
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCC
QNLVITDLNVGIFLWISLSSIAPIGLLMSGYSSNNKYALLGGLRAAAQSISYEIPLALAV
CCEEEEECCCCEEEEEEHHHHCHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHH
LAIAMMSNSLSTIDIVEQQSGYGILGWNIWRQPVGFLIFWIAALAECERLPFDLPEAEEE
HHHHHHHCCCCHHHHEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LVAGYQTEYAGMKFGLFYVGSYVNLVLSALIVSILYLGGWEFPIPLDKLAGWLNVAPSTP
HHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCH
WLQVITASLGIIMTLVKTYALVFIAVLLRWTLPRVRIDQLLNFGWKFLLPVALVNLLLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALKLAFPIAFGG
HHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA