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The map label for this gene is pcoR [H]

Identifier: 170077481

GI number: 170077481

Start: 886867

End: 887667

Strand: Direct

Name: pcoR [H]

Synonym: SYNPCC7002_A0859

Alternate gene names: 170077481

Gene position: 886867-887667 (Clockwise)

Preceding gene: 170077477

Following gene: 170077482

Centisome position: 29.48

GC content: 40.45

Gene sequence:

>801_bases
ATGACGAAAATTTTGATTATTGAGGATGAAGCAGAAACCCGTAATGTTTTCCTTAAGTGCCTAGAATTTGAAGGCTTTAA
AACCTGTGCTGCAAGTAATGCTTTAGATGGTATCGAACTGGCATTAAACGAACAACCAAATTTGATTGTGTGTGACATTC
TCATGCCTGACATGGATGGTTACTTCGTGTTGTCAAAAATACGCCGCTCACCTAAAACAACCGCGATTCCTTTTATCTTT
CTCACTGCCAAAGTTACTATGGCCGAGCTTCGCTATGGTATGCAGCTCGGAGCAGACGATTACCTGACCAAGCCTTGCAC
AGTTGAACAATTTCTAGGGGCAATTAATGTTCGACTAAAGCGACAACAAGACACGATTGAAAATCACCATCTAGATTCGA
CAAAAAATAAAACAGTTGTTTCTTCTGGTGCCGAAATCGACTTTCCATTAACAGATATCGATCGCGATTTTTCTTTTCCC
TACTCCAGCAATTTAAATCGAGCGTTTGATTTTATTGAAGATCATTACCATCAACCCATTAAAATCAAGGCGATCGCCGA
GGAAGTTGGCTATTCCACTTCCTACCTGAGTAATTTAGTTCAAAAAGAAACTGGCTACACAGTCAAACAGTGGATTATCG
CAAGGCGCATGCTGCAGGCTCGCAAACTATTGAAAAATACAAACAAGCCAATCCATAAAATTGCAGAATTATGTGGCTAC
CATGATGCGGGCTACTTTACCAACCAATTCCGGCGATTCCATGGAAAAACACCATTAAATTGGCGTTCTGAGCAAATATA
G

Upstream 100 bases:

>100_bases
ATCTAAGCAAGAACACAATATCAACCTGCTCTTTAAGCCCTAGGGTATGGGGTGCTCTACTTGGCAGCATAAATGATCAA
TTTTTGGAAACAAGAAGGCA

Downstream 100 bases:

>100_bases
CCTGTCTTCTTGTGGGCTGCCAGGACAGTTTTTCACAAAAACCAACTGAGAATAACATCTTCGGAAAAGACTTTTCTGTA
ATTGATTTAACAAAAAAAGC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTKILIIEDEAETRNVFLKCLEFEGFKTCAASNALDGIELALNEQPNLIVCDILMPDMDGYFVLSKIRRSPKTTAIPFIF
LTAKVTMAELRYGMQLGADDYLTKPCTVEQFLGAINVRLKRQQDTIENHHLDSTKNKTVVSSGAEIDFPLTDIDRDFSFP
YSSNLNRAFDFIEDHYHQPIKIKAIAEEVGYSTSYLSNLVQKETGYTVKQWIIARRMLQARKLLKNTNKPIHKIAELCGY
HDAGYFTNQFRRFHGKTPLNWRSEQI

Sequences:

>Translated_266_residues
MTKILIIEDEAETRNVFLKCLEFEGFKTCAASNALDGIELALNEQPNLIVCDILMPDMDGYFVLSKIRRSPKTTAIPFIF
LTAKVTMAELRYGMQLGADDYLTKPCTVEQFLGAINVRLKRQQDTIENHHLDSTKNKTVVSSGAEIDFPLTDIDRDFSFP
YSSNLNRAFDFIEDHYHQPIKIKAIAEEVGYSTSYLSNLVQKETGYTVKQWIIARRMLQARKLLKNTNKPIHKIAELCGY
HDAGYFTNQFRRFHGKTPLNWRSEQI
>Mature_265_residues
TKILIIEDEAETRNVFLKCLEFEGFKTCAASNALDGIELALNEQPNLIVCDILMPDMDGYFVLSKIRRSPKTTAIPFIFL
TAKVTMAELRYGMQLGADDYLTKPCTVEQFLGAINVRLKRQQDTIENHHLDSTKNKTVVSSGAEIDFPLTDIDRDFSFPY
SSNLNRAFDFIEDHYHQPIKIKAIAEEVGYSTSYLSNLVQKETGYTVKQWIIARRMLQARKLLKNTNKPIHKIAELCGYH
DAGYFTNQFRRFHGKTPLNWRSEQI

Specific function: Probable member of a two-component regulatory system pcoS/pcoR. May be involved in the activation of copper resistance gene operon pcoABCD by binding to a specific site on the cop operon promoter (copper box) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=124, Percent_Identity=36.2903225806452, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87082012, Length=154, Percent_Identity=33.1168831168831, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786911, Length=125, Percent_Identity=32, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786599, Length=149, Percent_Identity=30.8724832214765, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789809, Length=141, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787487, Length=103, Percent_Identity=34.9514563106796, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790552, Length=126, Percent_Identity=30.952380952381, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081928, Length=94, Percent_Identity=31.9148936170213, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788550, Length=131, Percent_Identity=29.0076335877863, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788394, Length=141, Percent_Identity=25.531914893617, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790863, Length=102, Percent_Identity=31.3725490196078, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790497, Length=92, Percent_Identity=35.8695652173913, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI2367329, Length=147, Percent_Identity=29.9319727891156, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 30555; Mature: 30424

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKILIIEDEAETRNVFLKCLEFEGFKTCAASNALDGIELALNEQPNLIVCDILMPDMDG
CCEEEEEECCCHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCC
YFVLSKIRRSPKTTAIPFIFLTAKVTMAELRYGMQLGADDYLTKPCTVEQFLGAINVRLK
HHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHEEE
RQQDTIENHHLDSTKNKTVVSSGAEIDFPLTDIDRDFSFPYSSNLNRAFDFIEDHYHQPI
CHHHHHHHCCCCCCCCCEEEECCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCE
KIKAIAEEVGYSTSYLSNLVQKETGYTVKQWIIARRMLQARKLLKNTNKPIHKIAELCGY
EEEEHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
HDAGYFTNQFRRFHGKTPLNWRSEQI
CCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TKILIIEDEAETRNVFLKCLEFEGFKTCAASNALDGIELALNEQPNLIVCDILMPDMDG
CEEEEEECCCHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCC
YFVLSKIRRSPKTTAIPFIFLTAKVTMAELRYGMQLGADDYLTKPCTVEQFLGAINVRLK
HHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHEEE
RQQDTIENHHLDSTKNKTVVSSGAEIDFPLTDIDRDFSFPYSSNLNRAFDFIEDHYHQPI
CHHHHHHHCCCCCCCCCEEEECCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCE
KIKAIAEEVGYSTSYLSNLVQKETGYTVKQWIIARRMLQARKLLKNTNKPIHKIAELCGY
EEEEHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
HDAGYFTNQFRRFHGKTPLNWRSEQI
CCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8594334; 9141682 [H]