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The map label for this gene is xorIIM [H]

Identifier: 170077471

GI number: 170077471

Start: 875468

End: 876709

Strand: Reverse

Name: xorIIM [H]

Synonym: SYNPCC7002_A0849

Alternate gene names: 170077471

Gene position: 876709-875468 (Counterclockwise)

Preceding gene: 170077472

Following gene: 170077470

Centisome position: 29.15

GC content: 52.66

Gene sequence:

>1242_bases
GTGAACCAAAGGCCCCTAGCCATTGATTTGTTTGCCGGATGCGGCGGAATGTCCCTGGGGCTAGAAGCGGCGGGCTTTGA
TGTGGTCGCAGCGGTAGAGATTGATCCCGTCCATGCCCTCGTTCACGAAGTAAATTTTCCCTATGGCGTCACCTTTTGCC
GGGATATTCGCCACCTGCAATGGCCAGAAATGCGCCAAGCCATCGAACGGCGGGGCTATTCAACGGCAGACATTGATTTA
CTCACGGGTGGCCCTCCCTGCCAGGGATTTTCGGTGATGGGCAAACGACAATTGGGTGACCCGCGCAATCAATTGATCTT
TGAATATGTCCGTCTGTTACGGGACATTCAACCCAAATATTTCATTTTTGAAAATGTCCAGGGCCTGACTGGGCAACGCC
ACCAAGGGATGCTAAAACAGCTTTGCCAATCTTTAGGTGAGGCTGGCTACCATGTTTTGCCCCCCCAGGTGCTCAATGGT
GCTGACTATGGTGCTCCCCAACGACGTAAACGCTTAATTCTCTTGGGATATCGTCGGGATGTTCCCTCGGTGGCCTATCC
AGCGCCGAGCCATGGCCCCGGCCTAGCACCCTATGTTACTGTCCACGAGGCGATCGCCGATTTAGAAACTATCCCTGTTT
TTACAGACATTGACCGGGGCATTGTCCCCCCCGAACCTTTGGGAACCTTTGGGCGATCGCTCCATGAGCAGTTTCGCCAT
TGCCATTCCCGCCACCTAGAACCTAATTTTCTCTGGGGCCACCTTGGTTCTCAGCATCAACCCGAAATCCAAGCCCGTTT
CCGAGCCACTCCCCCTGGCAAAAAAGAAGCCATTAGTCGCCTCTTTAAGCTGGATGCCCAGGGTCTCAGCAATACTTTAC
GGGCCGGCACTCCCACCGAAAAAGGCTCCTTTACGGCTCCTAGGCCGATTCATTACCAACTGCCCCGCTGTATTTCGATT
CGCGAAGCTGCCCGCCTACATACCTTCCCCGATTGGTTTCAGTTTCATCGCAAGGTTTGGCATGGCTTCCGGGAAATTGG
TAATGCCGTGCTGCCGCTCTTGGCCCAAAAAATTGCCCAAGAAATTATTCACACCTTAGACATTCAGCCGGATTTGCTCC
CCCAAAAAACAATTCATATTACCCAAACTGATGCTTTATGGTATCCCCTTGGGCAAGCTAGTCAATATTGGGAAATTCCG
CGACATTTAGTGCCACGCCGTCGCCGTCTTTCTCCACCTTAA

Upstream 100 bases:

>100_bases
CGAGCACCGAGGCGATCATTTTCGTCACCTTTGCCAAGCTCTATAGAGCCAAAACCCTTTAGCATTAAAGAGAATTGCAA
ACACCTACTGGGAGCGCACT

Downstream 100 bases:

>100_bases
AAACTCATAAAAATCATATTTTTTGAAACCCAATTTCTCACCTATGATAACTATATTCCTATTTCGCAGACTATCTTTTT
AAGCCCCGATAACCTATTAG

Product: site-specific DNA-methyltransferase

Products: NA

Alternate protein names: M.XorII; Cytosine-specific methyltransferase XorII [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MNQRPLAIDLFAGCGGMSLGLEAAGFDVVAAVEIDPVHALVHEVNFPYGVTFCRDIRHLQWPEMRQAIERRGYSTADIDL
LTGGPPCQGFSVMGKRQLGDPRNQLIFEYVRLLRDIQPKYFIFENVQGLTGQRHQGMLKQLCQSLGEAGYHVLPPQVLNG
ADYGAPQRRKRLILLGYRRDVPSVAYPAPSHGPGLAPYVTVHEAIADLETIPVFTDIDRGIVPPEPLGTFGRSLHEQFRH
CHSRHLEPNFLWGHLGSQHQPEIQARFRATPPGKKEAISRLFKLDAQGLSNTLRAGTPTEKGSFTAPRPIHYQLPRCISI
REAARLHTFPDWFQFHRKVWHGFREIGNAVLPLLAQKIAQEIIHTLDIQPDLLPQKTIHITQTDALWYPLGQASQYWEIP
RHLVPRRRRLSPP

Sequences:

>Translated_413_residues
MNQRPLAIDLFAGCGGMSLGLEAAGFDVVAAVEIDPVHALVHEVNFPYGVTFCRDIRHLQWPEMRQAIERRGYSTADIDL
LTGGPPCQGFSVMGKRQLGDPRNQLIFEYVRLLRDIQPKYFIFENVQGLTGQRHQGMLKQLCQSLGEAGYHVLPPQVLNG
ADYGAPQRRKRLILLGYRRDVPSVAYPAPSHGPGLAPYVTVHEAIADLETIPVFTDIDRGIVPPEPLGTFGRSLHEQFRH
CHSRHLEPNFLWGHLGSQHQPEIQARFRATPPGKKEAISRLFKLDAQGLSNTLRAGTPTEKGSFTAPRPIHYQLPRCISI
REAARLHTFPDWFQFHRKVWHGFREIGNAVLPLLAQKIAQEIIHTLDIQPDLLPQKTIHITQTDALWYPLGQASQYWEIP
RHLVPRRRRLSPP
>Mature_413_residues
MNQRPLAIDLFAGCGGMSLGLEAAGFDVVAAVEIDPVHALVHEVNFPYGVTFCRDIRHLQWPEMRQAIERRGYSTADIDL
LTGGPPCQGFSVMGKRQLGDPRNQLIFEYVRLLRDIQPKYFIFENVQGLTGQRHQGMLKQLCQSLGEAGYHVLPPQVLNG
ADYGAPQRRKRLILLGYRRDVPSVAYPAPSHGPGLAPYVTVHEAIADLETIPVFTDIDRGIVPPEPLGTFGRSLHEQFRH
CHSRHLEPNFLWGHLGSQHQPEIQARFRATPPGKKEAISRLFKLDAQGLSNTLRAGTPTEKGSFTAPRPIHYQLPRCISI
REAARLHTFPDWFQFHRKVWHGFREIGNAVLPLLAQKIAQEIIHTLDIQPDLLPQKTIHITQTDALWYPLGQASQYWEIP
RHLVPRRRRLSPP

Specific function: This methylase recognizes the double-stranded sequence CGATCG, causes specific methylation on C-? on both strands and protects the DNA from cleavage by the XorII endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4503351, Length=193, Percent_Identity=29.5336787564767, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI195927037, Length=178, Percent_Identity=30.3370786516854, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1788271, Length=200, Percent_Identity=31, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 46733; Mature: 46733

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00094 C5_MTASE_1 ; PS00095 C5_MTASE_2 ; PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRPLAIDLFAGCGGMSLGLEAAGFDVVAAVEIDPVHALVHEVNFPYGVTFCRDIRHLQ
CCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHCCCCCHHHHHHHHHHCC
WPEMRQAIERRGYSTADIDLLTGGPPCQGFSVMGKRQLGDPRNQLIFEYVRLLRDIQPKY
CHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHCHHHCCCHHHHHHHHHHHHHHHCCCCE
FIFENVQGLTGQRHQGMLKQLCQSLGEAGYHVLPPQVLNGADYGAPQRRKRLILLGYRRD
EEEECCCCCCCCHHHHHHHHHHHHHHHCCCEECCHHHHCCCCCCCCHHHCEEEEEEECCC
VPSVAYPAPSHGPGLAPYVTVHEAIADLETIPVFTDIDRGIVPPEPLGTFGRSLHEQFRH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHH
CHSRHLEPNFLWGHLGSQHQPEIQARFRATPPGKKEAISRLFKLDAQGLSNTLRAGTPTE
HHHCCCCCCEEECCCCCCCCCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
KGSFTAPRPIHYQLPRCISIREAARLHTFPDWFQFHRKVWHGFREIGNAVLPLLAQKIAQ
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIIHTLDIQPDLLPQKTIHITQTDALWYPLGQASQYWEIPRHLVPRRRRLSPP
HHHHHHCCCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure
MNQRPLAIDLFAGCGGMSLGLEAAGFDVVAAVEIDPVHALVHEVNFPYGVTFCRDIRHLQ
CCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHCCCCCHHHHHHHHHHCC
WPEMRQAIERRGYSTADIDLLTGGPPCQGFSVMGKRQLGDPRNQLIFEYVRLLRDIQPKY
CHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHCHHHCCCHHHHHHHHHHHHHHHCCCCE
FIFENVQGLTGQRHQGMLKQLCQSLGEAGYHVLPPQVLNGADYGAPQRRKRLILLGYRRD
EEEECCCCCCCCHHHHHHHHHHHHHHHCCCEECCHHHHCCCCCCCCHHHCEEEEEEECCC
VPSVAYPAPSHGPGLAPYVTVHEAIADLETIPVFTDIDRGIVPPEPLGTFGRSLHEQFRH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHH
CHSRHLEPNFLWGHLGSQHQPEIQARFRATPPGKKEAISRLFKLDAQGLSNTLRAGTPTE
HHHCCCCCCEEECCCCCCCCCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
KGSFTAPRPIHYQLPRCISIREAARLHTFPDWFQFHRKVWHGFREIGNAVLPLLAQKIAQ
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIIHTLDIQPDLLPQKTIHITQTDALWYPLGQASQYWEIPRHLVPRRRRLSPP
HHHHHHCCCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8078464 [H]