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The map label for this gene is grpE [H]

Identifier: 170077318

GI number: 170077318

Start: 725030

End: 725779

Strand: Reverse

Name: grpE [H]

Synonym: SYNPCC7002_A0695

Alternate gene names: 170077318

Gene position: 725779-725030 (Counterclockwise)

Preceding gene: 170077321

Following gene: 170077317

Centisome position: 24.13

GC content: 50.8

Gene sequence:

>750_bases
ATGGTAGAAGACGCGAAAAATCTTGATAGCCCAATTGATCCAGGAAGCACGCCCGAGTCTGTTTCCGACGAGGCCCCCGA
GACAACCATCGAGTCTAACCTTGGGGAGGATGCCACAACGATCGAAGCTCAAGGAGAAACAAACACCGATACCGCAGATC
AAGCCCCTGACCAGGAGGTCGATGACACGCCCCTCGATGGTGCCGAACTAGAAGCTGTCATTGCCGCTCTCCAGCAGGAG
GTCAGTACCCTGCGCCAACAGCTCAGTACCCAAAGTCAACAAACCGAAAATTTCAAAAGCCAATATATGCGGATCGCCGC
CGATTTTGAAAATTTCCGCAAGCGTACCAGCAAAGAAAAAGAAGAAATGGAATTGCGAATCAAGTGCAATACCGTCAATG
AAATCTTGGGCGCCGTTGACAACTTTGAGCGGGCCAGATTGCAGATCAAGCCCTCCACCGATGGCGAAATGACAATCCAC
AAAAGCTATCAAGGGGTCTATAAACAACTTGTCGATGGATTGAAAAAAATTGGTGTCTCTGCCATGCGTCCAGAAGGAGA
AGAATTTGATCCCAATTTCCACGAGGCGATCTTCCAAGAACCCACCAGTGAGCACCCAGAAGGCACTGTGATTGAGCAGG
TCGTGCGTGGCTATCTTTTAGGAGACATGGTGTTACGCCATGCCATGGTTAAGGTTGCCGCCGCGCCTGAGGAACCCCCC
AGCGGTGAAACCAGCACCAGTGAAAGTTAA

Upstream 100 bases:

>100_bases
CTAGGTTAGGCGATCGCCCACCATCACTACTAGGATAGAAACGACTAAAAACATCGATATAACCCAATAGCCAATCCTAA
AACAACTAGTTCAAGCAACC

Downstream 100 bases:

>100_bases
GGGTTAAACCCAATTTTTGCGATGGGGCCTATAGACATAAACTGTTGTAGTTCCTGGCCCCAGACAAAATCTTCAGTAGT
ATTGAAAAAATCCTTATCGT

Product: heat shock protein

Products: NA

Alternate protein names: HSP-70 cofactor [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MVEDAKNLDSPIDPGSTPESVSDEAPETTIESNLGEDATTIEAQGETNTDTADQAPDQEVDDTPLDGAELEAVIAALQQE
VSTLRQQLSTQSQQTENFKSQYMRIAADFENFRKRTSKEKEEMELRIKCNTVNEILGAVDNFERARLQIKPSTDGEMTIH
KSYQGVYKQLVDGLKKIGVSAMRPEGEEFDPNFHEAIFQEPTSEHPEGTVIEQVVRGYLLGDMVLRHAMVKVAAAPEEPP
SGETSTSES

Sequences:

>Translated_249_residues
MVEDAKNLDSPIDPGSTPESVSDEAPETTIESNLGEDATTIEAQGETNTDTADQAPDQEVDDTPLDGAELEAVIAALQQE
VSTLRQQLSTQSQQTENFKSQYMRIAADFENFRKRTSKEKEEMELRIKCNTVNEILGAVDNFERARLQIKPSTDGEMTIH
KSYQGVYKQLVDGLKKIGVSAMRPEGEEFDPNFHEAIFQEPTSEHPEGTVIEQVVRGYLLGDMVLRHAMVKVAAAPEEPP
SGETSTSES
>Mature_249_residues
MVEDAKNLDSPIDPGSTPESVSDEAPETTIESNLGEDATTIEAQGETNTDTADQAPDQEVDDTPLDGAELEAVIAALQQE
VSTLRQQLSTQSQQTENFKSQYMRIAADFENFRKRTSKEKEEMELRIKCNTVNEILGAVDNFERARLQIKPSTDGEMTIH
KSYQGVYKQLVDGLKKIGVSAMRPEGEEFDPNFHEAIFQEPTSEHPEGTVIEQVVRGYLLGDMVLRHAMVKVAAAPEEPP
SGETSTSES

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with dnaK and grpE. It is the nucleotide exchange factor for dnaK and may function as a thermosensor. Unfolded

COG id: COG0576

COG function: function code O; Molecular chaperone GrpE (heat shock protein)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grpE family [H]

Homologues:

Organism=Escherichia coli, GI1788967, Length=158, Percent_Identity=28.4810126582279, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324806, Length=169, Percent_Identity=31.3609467455621, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: 2359 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000740
- InterPro:   IPR013805
- InterPro:   IPR009012 [H]

Pfam domain/function: PF01025 GrpE [H]

EC number: NA

Molecular weight: Translated: 27476; Mature: 27476

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: PS01071 GRPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEDAKNLDSPIDPGSTPESVSDEAPETTIESNLGEDATTIEAQGETNTDTADQAPDQEV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCC
DDTPLDGAELEAVIAALQQEVSTLRQQLSTQSQQTENFKSQYMRIAADFENFRKRTSKEK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EEMELRIKCNTVNEILGAVDNFERARLQIKPSTDGEMTIHKSYQGVYKQLVDGLKKIGVS
HHHEEEEEECHHHHHHHHHHCHHHCEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCH
AMRPEGEEFDPNFHEAIFQEPTSEHPEGTVIEQVVRGYLLGDMVLRHAMVKVAAAPEEPP
HCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGETSTSES
CCCCCCCCC
>Mature Secondary Structure
MVEDAKNLDSPIDPGSTPESVSDEAPETTIESNLGEDATTIEAQGETNTDTADQAPDQEV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCC
DDTPLDGAELEAVIAALQQEVSTLRQQLSTQSQQTENFKSQYMRIAADFENFRKRTSKEK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EEMELRIKCNTVNEILGAVDNFERARLQIKPSTDGEMTIHKSYQGVYKQLVDGLKKIGVS
HHHEEEEEECHHHHHHHHHHCHHHCEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCH
AMRPEGEEFDPNFHEAIFQEPTSEHPEGTVIEQVVRGYLLGDMVLRHAMVKVAAAPEEPP
HCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGETSTSES
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA