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The map label for this gene is pdxA [H]

Identifier: 170077294

GI number: 170077294

Start: 701132

End: 702208

Strand: Reverse

Name: pdxA [H]

Synonym: SYNPCC7002_A0671

Alternate gene names: 170077294

Gene position: 702208-701132 (Counterclockwise)

Preceding gene: 170077295

Following gene: 170077292

Centisome position: 23.34

GC content: 52.46

Gene sequence:

>1077_bases
ATGAAAATTCGCCTCGCTTTGACTATTGGTGATCCGGCCGGGATTGGCCCAGAGGTACTTTTAAAAGCTCTGGCGGATCC
AGAAATTAGAGCGCTTTGTCCGATGAGGGTCATTGGCGATCGCCCCTTGCTCGAAAAAACCTATCAGCACCTCAAAACTC
GGACGGAATCTGATCTCCTTGATCCCAGTGAGTTAGAGATTGTCGAACCGAGTGGCAATGAATTTTTGAGGAATTTCACC
TGGGGAGAAGGTTCGGCAGAAACAGGCGATCGCGCTTTCCAGTACCTCAACACGGCGATTGAAAAAACCCTGGGGGGAGA
ATTTTCGGGGATTGTCACCGCCCCCATTGCTAAATCCCTCTGGAAAGCAGCCGGCCACGACTACCCCGGCCAAACGGAGG
TTCTCGCCCAAAAGAGCCAAACCACCCGCTATGGCATGGCCTTTATTGGCAAATCTCCCTATACAGGCTGGACATTGCGG
AGCCTGCTAGCGACGACCCACATTCCTCTAAAAGCGGTGCCAGAAACCTTGAATCCAGGGCTGATGGATTTGAAACTTAG
TCTTCTTTTAGAGTCGCTCCAGCAGGATTTTGGGTTAGAAAATCCCCAGGTGGCGATCGCCGGTTTAAATCCCCACAGTG
GCGAAAATGGTCAATTGGGCACCGAAGAAATGGACTGGCTTAACGGTTGGCTAGAAGATGCGCGACAAAAATATCCCAAT
GCAACTCTGTTAGGGCTTTATCCTCCGGATACCATGTGGGTCAATGCGGGCAAAGCTTGGTATGGCAAACCAGAATTCAA
ACCCGCCGCCGATGCGTATCTGGCTCTCTACCACGACCAAGGGTTAATCCCAGTGAAACTGATGGCCTTTGACTACGCGA
TCAATACCACCATTGGTTTACCCTTTATTCGGACTTCCCCCGACCACGGCACCGCCTTCGACATTGCGGGGCAAGGCAGC
GCCAATCCCACCAGCATGAAAGAAGCGATCAAACTGGCCGTCAGCATTAGCCAAAATCGCGCCGCCACCACTGTCCCCCC
ACTTCTAACCCCCCCAGATCGCTCGTTGCTTGGATGA

Upstream 100 bases:

>100_bases
CCTGAAGTTTGAACCGAAGGCTGAGTAGACGCCCTCACACCCTCCGCCTTCGGCACCTCCCTCCAGGGAGGATTTTTTAG
TTCGTTGACTATTCTCCCCT

Downstream 100 bases:

>100_bases
GGGGCGTTTTGTCCGGGGCGAATAGTTCAAGGGAAATTTGGCCCCGCAGGGTATCCTGACAACAAAACCGTAGGCCCGTG
TGGGTCGGTGCTCGCAGGGG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKIRLALTIGDPAGIGPEVLLKALADPEIRALCPMRVIGDRPLLEKTYQHLKTRTESDLLDPSELEIVEPSGNEFLRNFT
WGEGSAETGDRAFQYLNTAIEKTLGGEFSGIVTAPIAKSLWKAAGHDYPGQTEVLAQKSQTTRYGMAFIGKSPYTGWTLR
SLLATTHIPLKAVPETLNPGLMDLKLSLLLESLQQDFGLENPQVAIAGLNPHSGENGQLGTEEMDWLNGWLEDARQKYPN
ATLLGLYPPDTMWVNAGKAWYGKPEFKPAADAYLALYHDQGLIPVKLMAFDYAINTTIGLPFIRTSPDHGTAFDIAGQGS
ANPTSMKEAIKLAVSISQNRAATTVPPLLTPPDRSLLG

Sequences:

>Translated_358_residues
MKIRLALTIGDPAGIGPEVLLKALADPEIRALCPMRVIGDRPLLEKTYQHLKTRTESDLLDPSELEIVEPSGNEFLRNFT
WGEGSAETGDRAFQYLNTAIEKTLGGEFSGIVTAPIAKSLWKAAGHDYPGQTEVLAQKSQTTRYGMAFIGKSPYTGWTLR
SLLATTHIPLKAVPETLNPGLMDLKLSLLLESLQQDFGLENPQVAIAGLNPHSGENGQLGTEEMDWLNGWLEDARQKYPN
ATLLGLYPPDTMWVNAGKAWYGKPEFKPAADAYLALYHDQGLIPVKLMAFDYAINTTIGLPFIRTSPDHGTAFDIAGQGS
ANPTSMKEAIKLAVSISQNRAATTVPPLLTPPDRSLLG
>Mature_358_residues
MKIRLALTIGDPAGIGPEVLLKALADPEIRALCPMRVIGDRPLLEKTYQHLKTRTESDLLDPSELEIVEPSGNEFLRNFT
WGEGSAETGDRAFQYLNTAIEKTLGGEFSGIVTAPIAKSLWKAAGHDYPGQTEVLAQKSQTTRYGMAFIGKSPYTGWTLR
SLLATTHIPLKAVPETLNPGLMDLKLSLLLESLQQDFGLENPQVAIAGLNPHSGENGQLGTEEMDWLNGWLEDARQKYPN
ATLLGLYPPDTMWVNAGKAWYGKPEFKPAADAYLALYHDQGLIPVKLMAFDYAINTTIGLPFIRTSPDHGTAFDIAGQGS
ANPTSMKEAIKLAVSISQNRAATTVPPLLTPPDRSLLG

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=342, Percent_Identity=33.6257309941521, Blast_Score=179, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 38953; Mature: 38953

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRLALTIGDPAGIGPEVLLKALADPEIRALCPMRVIGDRPLLEKTYQHLKTRTESDLL
CEEEEEEEECCCCCCCHHHHHHHHCCCCHHHHCCHHHHCCCHHHHHHHHHHHHCCHHCCC
DPSELEIVEPSGNEFLRNFTWGEGSAETGDRAFQYLNTAIEKTLGGEFSGIVTAPIAKSL
CCCCEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
WKAAGHDYPGQTEVLAQKSQTTRYGMAFIGKSPYTGWTLRSLLATTHIPLKAVPETLNPG
HHHHCCCCCCCHHHHHHHCCCHHHCEEEECCCCCCHHHHHHHHHHCCCCHHHCCHHCCCC
LMDLKLSLLLESLQQDFGLENPQVAIAGLNPHSGENGQLGTEEMDWLNGWLEDARQKYPN
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
ATLLGLYPPDTMWVNAGKAWYGKPEFKPAADAYLALYHDQGLIPVKLMAFDYAINTTIGL
CEEEEECCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEHHHHCCEECC
PFIRTSPDHGTAFDIAGQGSANPTSMKEAIKLAVSISQNRAATTVPPLLTPPDRSLLG
CEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHCC
>Mature Secondary Structure
MKIRLALTIGDPAGIGPEVLLKALADPEIRALCPMRVIGDRPLLEKTYQHLKTRTESDLL
CEEEEEEEECCCCCCCHHHHHHHHCCCCHHHHCCHHHHCCCHHHHHHHHHHHHCCHHCCC
DPSELEIVEPSGNEFLRNFTWGEGSAETGDRAFQYLNTAIEKTLGGEFSGIVTAPIAKSL
CCCCEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
WKAAGHDYPGQTEVLAQKSQTTRYGMAFIGKSPYTGWTLRSLLATTHIPLKAVPETLNPG
HHHHCCCCCCCHHHHHHHCCCHHHCEEEECCCCCCHHHHHHHHHHCCCCHHHCCHHCCCC
LMDLKLSLLLESLQQDFGLENPQVAIAGLNPHSGENGQLGTEEMDWLNGWLEDARQKYPN
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
ATLLGLYPPDTMWVNAGKAWYGKPEFKPAADAYLALYHDQGLIPVKLMAFDYAINTTIGL
CEEEEECCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEHHHHCCEECC
PFIRTSPDHGTAFDIAGQGSANPTSMKEAIKLAVSISQNRAATTVPPLLTPPDRSLLG
CEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]