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The map label for this gene is atpD [H]

Identifier: 170026430

GI number: 170026430

Start: 4664123

End: 4665505

Strand: Direct

Name: atpD [H]

Synonym: YPK_4226

Alternate gene names: 170026430

Gene position: 4664123-4665505 (Clockwise)

Preceding gene: 170026429

Following gene: 170026431

Centisome position: 99.46

GC content: 49.96

Gene sequence:

>1383_bases
ATGGCTACTGGAAAGATTATCCAGGTAATCGGCGCCGTAGTGGACGTCGAATTCCCCCAAGACGCTGTACCAAAAGTGTA
CAACGCCCTTGAGGTAGAAGGTACAACTGAAAAGTTAGTGCTGGAAGTTCAGCAACAGTTGGGCGGTGGTGTTGTTCGTT
GTATCGCAATGGGCTCTTCCGATGGTCTGAGCCGTGGGTTGAAAGTAACCAACCTAGAACACCCGATCGAAGTACCGGTT
GGTAAAGCGACCCTTGGCCGTATCATGAACGTATTGGGTGAACCAATCGACATGAAAGGTCCTATCGGTGAAGAAGAGCG
TTGGGCAATCCATCGCGAAGCGCCTTCTTATGAAGAGCTTGCTAGCTCACAAGATCTGTTAGAAACCGGTATCAAGGTTA
TGGACCTGATTTGTCCGTTTGCTAAGGGCGGTAAAGTCGGTCTGTTCGGTGGTGCGGGTGTAGGTAAAACAGTAAACATG
ATGGAGCTGATCCGTAACATCGCGATCGAGCACTCTGGGTATTCTGTATTTGCCGGTGTAGGTGAGCGTACCCGTGAGGG
TAATGACTTCTACCATGAAATGACTGACTCCAACGTTTTGGACAAAGTATCCTTGGTTTACGGCCAGATGAATGAGCCAC
CAGGTAACCGTCTACGCGTTGCACTGACCGGCCTGACCATGGCGGAGAAATTCCGTGATGAAGGTCGTGACGTACTGCTG
TTCATCGATAATATCTATCGTTATACCCTAGCTGGTACGGAAGTATCCGCATTGCTGGGTCGTATGCCATCAGCGGTAGG
TTATCAGCCAACACTGGCTGAAGAGATGGGTGTGTTGCAGGAACGTATTACTTCCACTAAGACGGGTTCAATCACCTCTG
TTCAGGCCGTTTATGTACCTGCGGATGACTTGACTGACCCATCACCAGCAACCACCTTTGCTCACTTGGATGCAACCGTC
GTTCTGAGTCGTCAAATCGCCTCTCTGGGTATTTATCCAGCAGTTGACCCACTTGACTCTACCAGCCGTCAGCTTGATCC
GTTGGTTGTTGGCCAGGAGCACTACGATGTAGCGCGTGGCGTGCAGTCTATTCTGCAACGTTACCAAGAGCTGAAAGATA
TCATCGCGATCTTGGGTATGGACGAGTTGTCAGAAGATGACAAACTGGTGGTATCCCGTGCGCGTAAGATTCAGCGCTTC
CTGTCTCAACCGTTCTTTGTGGCTGAAGTCTTCACCGGTTCACCGGGCAAGTTTGTGTCGCTGAAAGATACCATTCGTGG
TTTCAAAGGCATCATGAATGGCGACTATGACCACTTGCCGGAACAGGCGTTCTACATGGTCGGTACCATTGAAGAAGCAG
TGGAAAAAGCCAAGAAACTGTAA

Upstream 100 bases:

>100_bases
CTCTGACGCTTATAAAGTAAGTCGTCGGGGTGAGATAAGGTAGCCAACGCCCCAGCAATTTGAAGTATGGCGGGTAAACG
TATTACGTAGAGGATTCAAG

Downstream 100 bases:

>100_bases
CGCTGTTGACTGGAGGGTGACATGGCTGCAATGACTTACCATCTGGATGTTGTGAGCGCCGAGAAGAAAATGTTTTCAGG
CGTGGTACAAAAGATTCAGG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MATGKIIQVIGAVVDVEFPQDAVPKVYNALEVEGTTEKLVLEVQQQLGGGVVRCIAMGSSDGLSRGLKVTNLEHPIEVPV
GKATLGRIMNVLGEPIDMKGPIGEEERWAIHREAPSYEELASSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNM
MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
FIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATV
VLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEDDKLVVSRARKIQRF
LSQPFFVAEVFTGSPGKFVSLKDTIRGFKGIMNGDYDHLPEQAFYMVGTIEEAVEKAKKL

Sequences:

>Translated_460_residues
MATGKIIQVIGAVVDVEFPQDAVPKVYNALEVEGTTEKLVLEVQQQLGGGVVRCIAMGSSDGLSRGLKVTNLEHPIEVPV
GKATLGRIMNVLGEPIDMKGPIGEEERWAIHREAPSYEELASSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNM
MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
FIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATV
VLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEDDKLVVSRARKIQRF
LSQPFFVAEVFTGSPGKFVSLKDTIRGFKGIMNGDYDHLPEQAFYMVGTIEEAVEKAKKL
>Mature_459_residues
ATGKIIQVIGAVVDVEFPQDAVPKVYNALEVEGTTEKLVLEVQQQLGGGVVRCIAMGSSDGLSRGLKVTNLEHPIEVPVG
KATLGRIMNVLGEPIDMKGPIGEEERWAIHREAPSYEELASSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNMM
ELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLF
IDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVV
LSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEDDKLVVSRARKIQRFL
SQPFFVAEVFTGSPGKFVSLKDTIRGFKGIMNGDYDHLPEQAFYMVGTIEEAVEKAKKL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=466, Percent_Identity=71.4592274678112, Blast_Score=665, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=321, Percent_Identity=28.0373831775701, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI19913428, Length=362, Percent_Identity=25.1381215469613, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI50345984, Length=395, Percent_Identity=25.0632911392405, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4757810, Length=395, Percent_Identity=25.0632911392405, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI19913426, Length=357, Percent_Identity=24.0896358543417, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1790170, Length=460, Percent_Identity=93.2608695652174, Blast_Score=883, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=319, Percent_Identity=29.4670846394984, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790172, Length=420, Percent_Identity=25.4761904761905, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=466, Percent_Identity=69.7424892703863, Blast_Score=654, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=321, Percent_Identity=29.2834890965732, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=348, Percent_Identity=25.5747126436782, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=345, Percent_Identity=24.3478260869565, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71988080, Length=343, Percent_Identity=25.0728862973761, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=343, Percent_Identity=24.7813411078717, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988074, Length=369, Percent_Identity=24.6612466124661, Blast_Score=92, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322581, Length=458, Percent_Identity=68.5589519650655, Blast_Score=631, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=348, Percent_Identity=25.2873563218391, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319370, Length=368, Percent_Identity=25.5434782608696, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6320016, Length=233, Percent_Identity=28.3261802575107, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24638766, Length=465, Percent_Identity=69.8924731182796, Blast_Score=652, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=465, Percent_Identity=64.9462365591398, Blast_Score=595, Evalue=1e-170,
Organism=Drosophila melanogaster, GI24583992, Length=321, Percent_Identity=28.0373831775701, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI20129479, Length=331, Percent_Identity=27.190332326284, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583988, Length=321, Percent_Identity=27.4143302180685, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24583986, Length=321, Percent_Identity=27.4143302180685, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24583984, Length=321, Percent_Identity=27.4143302180685, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281361666, Length=348, Percent_Identity=24.7126436781609, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24646341, Length=348, Percent_Identity=24.7126436781609, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136796, Length=348, Percent_Identity=24.7126436781609, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24658560, Length=279, Percent_Identity=26.1648745519713, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=55.4347826086957, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50128; Mature: 49997

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGKIIQVIGAVVDVEFPQDAVPKVYNALEVEGTTEKLVLEVQQQLGGGVVRCIAMGSS
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCC
DGLSRGLKVTNLEHPIEVPVGKATLGRIMNVLGEPIDMKGPIGEEERWAIHREAPSYEEL
CHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHH
ASSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGV
HCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECC
GERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
CCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCCCEEEE
FIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVP
EEEHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
ADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCEEECCHHHHHHHH
VQSILQRYQELKDIIAILGMDELSEDDKLVVSRARKIQRFLSQPFFVAEVFTGSPGKFVS
HHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEE
LKDTIRGFKGIMNGDYDHLPEQAFYMVGTIEEAVEKAKKL
HHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATGKIIQVIGAVVDVEFPQDAVPKVYNALEVEGTTEKLVLEVQQQLGGGVVRCIAMGSS
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCC
DGLSRGLKVTNLEHPIEVPVGKATLGRIMNVLGEPIDMKGPIGEEERWAIHREAPSYEEL
CHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHH
ASSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGV
HCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECC
GERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
CCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCCCEEEE
FIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVP
EEEHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
ADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCEEECCHHHHHHHH
VQSILQRYQELKDIIAILGMDELSEDDKLVVSRARKIQRFLSQPFFVAEVFTGSPGKFVS
HHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEE
LKDTIRGFKGIMNGDYDHLPEQAFYMVGTIEEAVEKAKKL
HHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA