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The map label for this gene is atpA [H]

Identifier: 170026428

GI number: 170026428

Start: 4661501

End: 4663042

Strand: Direct

Name: atpA [H]

Synonym: YPK_4224

Alternate gene names: 170026428

Gene position: 4661501-4663042 (Clockwise)

Preceding gene: 170026427

Following gene: 170026429

Centisome position: 99.4

GC content: 50.0

Gene sequence:

>1542_bases
ATGCAACTGAATTCCACCGAAATCAGCGAACTGATCAAGCAGCGCATTGCTCAGTTCAATGTAGTGAGCGAAGCTCACAA
TGAAGGTACTATTGTTTCCGTTAGTGACGGGATCATTCGTGTACACGGTCTGGCCGATGTTATGCAGGGTGAGATGATCG
CACTGCCAGGCAACCGTTACGCAATCGCACTGAACTTGGAGCGCGACTCCGTAGGTGCTGTAGTTATGGGTCCGTACGCC
GATCTTGCCGAAGGCATGAAGGTTAAATGTACTGGCCGTATCCTGGAAGTTCCTGTCGGTCGTGGCCTGTTGGGGCGTGT
CGTCAATACTCTGGGTGAACCTATTGATGGTAAAGGTTCTATAGAAAACGACGGCTTCTCAGCTGTTGAAGCTATCGCAC
CTGGTGTTATCGAACGTCAATCCGTTGATGAGCCTGTTCAGACGGGCTATAAATCCGTCGATGCCATGATCCCAATTGGT
CGTGGTCAGCGTGAATTGATCATCGGTGACCGTCAGACAGGTAAAACTGCACTGGCGATTGATGCGATCATCAACCAACG
CGATTCCGGCATTAAATGTGTGTATGTTGCTATCGGCCAGAAAGCCTCTACTGTTGCAAACGTAGTGCGCAAGCTGGAAG
AACATGACGCATTAGCTAACACCATTGTGGTTGTTGCTACTGCATCAGAATCTGCAGCATTGCAGTATCTGGCACCTTAC
TCCGGTTGTGCCATGGGTGAATATTTCCGTGATCGCGGTGAGGATGCGCTGATTATTTATGATGACCTGTCTAAACAGGC
TGTTGCATATCGTCAAATCTCCTTGCTGCTTCGTCGTCCACCAGGTCGTGAAGCCTATCCTGGCGACGTATTCTACCTCC
ACTCCCGTTTGTTGGAGCGTGCTGCGCGTGTAAACGCTGAGTATGTTGAGGCCTTTACCAAGGGTGAAGTGAAAGGTAAA
ACAGGTTCTTTAACCGCATTACCTATCATTGAAACTCAGGCAGGTGACGTTTCTGCGTTTGTTCCGACCAACGTAATATC
GATTACAGATGGTCAGATCTTCCTGGAATCCAGCCTGTTTAACGCCGGTATTCGTCCTGCCGTTAACCCAGGTATCTCCG
TATCCCGTGTGGGTGGTGCAGCGCAGACCAAGATCATGAAAAAACTGTCCGGTGGTATTCGTACCGCTCTGGCACAGTAT
CGTGAGCTTGCAGCGTTCTCCCAGTTCGCATCCGATTTGGATGATGCAACACGTAAACAGCTGAGCCATGGTCAGAAAGT
GACCGAGCTTCTGAAACAGAAACAATATGCGCCGATGTCGGTTGCACAGCAGTCTCTGGTTCTGTTCGCAGCTGAACGTG
GTTATCTGGGTGATGTCGAGTTGGCGAAGGTGGGTAGCTTTGAAGCTGCACTGTTGGCATTTGCTGACCGTGAGCATGCT
GAGCTTCTGCAACAAATCAACCAAACTGGCGCGTATAACGATGAGATCGAGGCCAAGCTGAAAGGCATCCTCGATACATT
TAAGGCAACCCAGTCCTGGTAA

Upstream 100 bases:

>100_bases
GCGTAGTAATACGTGCAGGCGATATGGTGATAGATGGCAGCGTTCGCGGTCGTCTTGAACGCCTGGCAGACGTCTTGCAG
TCTTAAGGGGACTGGAGCAT

Downstream 100 bases:

>100_bases
CGCTATGCGGTCCTGCTTTTCGTTAGGAAAGCAGGCCGTCTGGTAATGAGGAGAAGCAGAAATGGCCGGCGCAAAAGAGA
TACGTTCCAAGATCGCCAGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGSIENDGFSAVEAIAPGVIERQSVDEPVQTGYKSVDAMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTVANVVRKLEEHDALANTIVVVATASESAALQYLAPY
SGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLSHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLGDVELAKVGSFEAALLAFADREHA
ELLQQINQTGAYNDEIEAKLKGILDTFKATQSW

Sequences:

>Translated_513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGSIENDGFSAVEAIAPGVIERQSVDEPVQTGYKSVDAMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTVANVVRKLEEHDALANTIVVVATASESAALQYLAPY
SGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLSHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLGDVELAKVGSFEAALLAFADREHA
ELLQQINQTGAYNDEIEAKLKGILDTFKATQSW
>Mature_513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGSIENDGFSAVEAIAPGVIERQSVDEPVQTGYKSVDAMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTVANVVRKLEEHDALANTIVVVATASESAALQYLAPY
SGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLSHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLGDVELAKVGSFEAALLAFADREHA
ELLQQINQTGAYNDEIEAKLKGILDTFKATQSW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=513, Percent_Identity=57.504873294347, Blast_Score=566, Evalue=1e-161,
Organism=Homo sapiens, GI4757810, Length=513, Percent_Identity=57.504873294347, Blast_Score=566, Evalue=1e-161,
Organism=Homo sapiens, GI32189394, Length=410, Percent_Identity=25.609756097561, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI19913426, Length=322, Percent_Identity=27.0186335403727, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19913428, Length=313, Percent_Identity=27.7955271565495, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI19913424, Length=259, Percent_Identity=27.7992277992278, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=93.5672514619883, Blast_Score=991, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=382, Percent_Identity=26.4397905759162, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788251, Length=345, Percent_Identity=26.0869565217391, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=55.7281553398058, Blast_Score=554, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=55.7281553398058, Blast_Score=554, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=52.0388349514563, Blast_Score=508, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17510931, Length=368, Percent_Identity=25.5434782608696, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=414, Percent_Identity=25.1207729468599, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=313, Percent_Identity=26.8370607028754, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=70.2127659574468, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=27.1653543307087, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=54.1910331384016, Blast_Score=560, Evalue=1e-160,
Organism=Saccharomyces cerevisiae, GI6322581, Length=472, Percent_Identity=26.271186440678, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319603, Length=370, Percent_Identity=25.9459459459459, Blast_Score=113, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=56.0311284046693, Blast_Score=554, Evalue=1e-158,
Organism=Drosophila melanogaster, GI281361666, Length=313, Percent_Identity=27.4760383386581, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646341, Length=313, Percent_Identity=27.4760383386581, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136796, Length=313, Percent_Identity=27.4760383386581, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24638766, Length=324, Percent_Identity=27.4691358024691, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=26.4797507788162, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24583988, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583986, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583984, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583992, Length=336, Percent_Identity=25.297619047619, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55201; Mature: 55201

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECHHHHHCCCEEEECCCEE
AIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGS
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
IENDGFSAVEAIAPGVIERQSVDEPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTALAI
CCCCCHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHEEECCCCCEEEEEECCCCCCHHEEH
DAIINQRDSGIKCVYVAIGQKASTVANVVRKLEEHDALANTIVVVATASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHCCCC
SGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECHHH
NAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQ
CCCCCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLGDVELAKVGSFEAALLAFADREHA
HHCCHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCCCCHHHHCCCHHHHHHHHCCCHHH
ELLQQINQTGAYNDEIEAKLKGILDTFKATQSW
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECHHHHHCCCEEEECCCEE
AIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGS
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
IENDGFSAVEAIAPGVIERQSVDEPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTALAI
CCCCCHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHEEECCCCCEEEEEECCCCCCHHEEH
DAIINQRDSGIKCVYVAIGQKASTVANVVRKLEEHDALANTIVVVATASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHCCCC
SGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECHHH
NAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQ
CCCCCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLGDVELAKVGSFEAALLAFADREHA
HHCCHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCCCCHHHHCCCHHHHHHHHCCCHHH
ELLQQINQTGAYNDEIEAKLKGILDTFKATQSW
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA