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The map label for this gene is atpF [H]

Identifier: 170026426

GI number: 170026426

Start: 4660468

End: 4660938

Strand: Direct

Name: atpF [H]

Synonym: YPK_4222

Alternate gene names: 170026426

Gene position: 4660468-4660938 (Clockwise)

Preceding gene: 170026425

Following gene: 170026427

Centisome position: 99.38

GC content: 49.26

Gene sequence:

>471_bases
GTGAATCTTAACGCAACAATCCTCGGCCAGGCCATCGCGTTTGTCCTGTTTGTCATATTTTGTATGAAGTATGTATGGCC
GCCAATTATGGCTGCTATCGAGAAGCGTCAACAAGAAATTGCTGACGGTCTCTCTTCTGCAGAGCGTGCCAAAAAAGATT
TGGACTTAGCGCAAGCCAATGCGACCGACCAACTGAAGAAAGCCAAAGCAGAGGCACAGGTGATCATTGAGCAAGCAAGT
AAACGCAAAGCTCAGATCCTTGATGAAGCTAAAGCAGAAGCTGAACAGGAACGTAACAAAATCGTGGCGCAAGCGCAGGC
AGAGATCGACGCCGAACGTAAGCGCGCTCGTGAAGAGTTGCGTAAGCAAGTCGCGATGTTGGCTATAGCTGGCGCCGAGA
AGATCATCGAACGTTCCGTGGATGAAGCTGCTAACAGCGACATCGTTGATAAACTGGTCGCTGAACTGTAA

Upstream 100 bases:

>100_bases
GTTGGTCTGGGTCTGTACGTGATGTTTGCTGTCGCGTAAGTAGAGTTTTCTCTACGGTGAAACTACACCAAACTATTAAC
TTTTAAAGAGGCATTGTGCT

Downstream 100 bases:

>100_bases
GGAGGGAGGGGCTGATGTCTGAATTTGTAACTGTAGCTCGCCCCTACGCCAAAGCAGCTTTTGACTTTGCTGTTGAGCAC
CAGGCAGTTGAGCGTTGGCA

Product: F0F1 ATP synthase subunit B

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(0) sector subunit b; ATPase subunit I; F-type ATPase subunit b; F-ATPase subunit b [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MNLNATILGQAIAFVLFVIFCMKYVWPPIMAAIEKRQQEIADGLSSAERAKKDLDLAQANATDQLKKAKAEAQVIIEQAS
KRKAQILDEAKAEAEQERNKIVAQAQAEIDAERKRAREELRKQVAMLAIAGAEKIIERSVDEAANSDIVDKLVAEL

Sequences:

>Translated_156_residues
MNLNATILGQAIAFVLFVIFCMKYVWPPIMAAIEKRQQEIADGLSSAERAKKDLDLAQANATDQLKKAKAEAQVIIEQAS
KRKAQILDEAKAEAEQERNKIVAQAQAEIDAERKRAREELRKQVAMLAIAGAEKIIERSVDEAANSDIVDKLVAEL
>Mature_156_residues
MNLNATILGQAIAFVLFVIFCMKYVWPPIMAAIEKRQQEIADGLSSAERAKKDLDLAQANATDQLKKAKAEAQVIIEQAS
KRKAQILDEAKAEAEQERNKIVAQAQAEIDAERKRAREELRKQVAMLAIAGAEKIIERSVDEAANSDIVDKLVAEL

Specific function: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) [H]

COG id: COG0711

COG function: function code C; F0F1-type ATP synthase, subunit b

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase B chain family [H]

Homologues:

Organism=Escherichia coli, GI1790174, Length=156, Percent_Identity=91.025641025641, Blast_Score=279, Evalue=5e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002146
- InterPro:   IPR005864 [H]

Pfam domain/function: PF00430 ATP-synt_B [H]

EC number: 3.6.3.14

Molecular weight: Translated: 17258; Mature: 17258

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNATILGQAIAFVLFVIFCMKYVWPPIMAAIEKRQQEIADGLSSAERAKKDLDLAQAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ATDQLKKAKAEAQVIIEQASKRKAQILDEAKAEAEQERNKIVAQAQAEIDAERKRAREEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKQVAMLAIAGAEKIIERSVDEAANSDIVDKLVAEL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
>Mature Secondary Structure
MNLNATILGQAIAFVLFVIFCMKYVWPPIMAAIEKRQQEIADGLSSAERAKKDLDLAQAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ATDQLKKAKAEAQVIIEQASKRKAQILDEAKAEAEQERNKIVAQAQAEIDAERKRAREEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKQVAMLAIAGAEKIIERSVDEAANSDIVDKLVAEL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]