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The map label for this gene is glnL [H]

Identifier: 170026397

GI number: 170026397

Start: 4623263

End: 4624312

Strand: Direct

Name: glnL [H]

Synonym: YPK_4190

Alternate gene names: 170026397

Gene position: 4623263-4624312 (Clockwise)

Preceding gene: 170026396

Following gene: 170026398

Centisome position: 98.59

GC content: 49.24

Gene sequence:

>1050_bases
ATGGCAACAGGCACGCTGCCCGATGCTGGGCAGATCCTCAATACTCTCATTAATAGCATTCTGCTGTTAGATGATGATTT
GGCTATTCATTATGCCAACCCCGCAGCCCAGCAACTTCTGGCGCAAAGCTCCCGTAAACTTTTTGGTACACCTCTGCCTG
ATTTATTAGGCTATTTTTCACTGAATATCGTGTTGATGCGAGAGAGTTTGCAAGCCGGGCAAGGGTTTACTGATAACGAA
GTGACATTAGTTGTTGATGGCCGGGCACATATTTTATCGCTGACCGCACAGTCCCTAGCGGAAGGGTTTATTCTGCTAGA
ATTAGCCCCGATGGATAATCAGCGCCGGTTAAGCCAAGAGCAATTGCAACACGCTCAACAAGTTGCCGCACGTGATTTAG
TGCGCGGATTGGCTCACGAGATTAAAAACCCACTCGGAGGCCTACGGGGCGCTGCGCAATTATTAGCTAAAGCGTTACCC
GATCCAGCGTTGCTGGAATATACCCAAGTGATTATTGAACAGGCGGATCGCCTACGTAATTTAGTTGATCGCTTGTTAGG
CCCACAGCGGCCTGGCCAACATATTACACAGAGTATTCATCAGGTTGCTGAGCGGGTTTGCCAATTAGTCTCATTGGAAA
AACCAGATAACGTCACGTTAATCCGCGACTATGATCCAAGCCTCCCTGAGCTTGCCCATGATCCAGACCAAATAGAACAA
GTGCTGCTGAATATCACCCGTAACGCATTACAGGCTCTCGGGGAGACTGGCGGCACAATTACACTTCGCACCCGAACCGC
TTTCCAAGTGACGCTACATGGCATGCGCTACCGTTTAGCCGCTCGGATTGATATTGAAGATGACGGTCCCGGTGTACCAA
CGCAATTACAAGATACCGTATTCTATCCGATGGTCAGTGGCCGCGAGGGCGGTACGGGTCTTGGTTTATCTATCGCCCGT
AATCTTATCGATCAGCATTCGGGTAAAATTGAATTTAACAGTTGGCCAGGACACACCGAGTTTTCGGTTTACCTGCCTAT
TCGCCAGTGA

Upstream 100 bases:

>100_bases
CTTGATTCTATTGCAACGGAACCAATAGGATGGACCGAATAGAAACATACCCTACAGATGAAGGGTATAAATGCACCGAA
ACTGTGCAGGAGTCTGCATT

Downstream 100 bases:

>100_bases
GGTTTCTATGCAACGAGGGATAGTCTGGATCGTCGATGACGATAGTTCCATCCGCTGGGTGCTTGAGCGCGCACTGACTG
GAGCGGGTCTAAACTGTGTC

Product: nitrogen regulation protein NR(II)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MATGTLPDAGQILNTLINSILLLDDDLAIHYANPAAQQLLAQSSRKLFGTPLPDLLGYFSLNIVLMRESLQAGQGFTDNE
VTLVVDGRAHILSLTAQSLAEGFILLELAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLAKALP
DPALLEYTQVIIEQADRLRNLVDRLLGPQRPGQHITQSIHQVAERVCQLVSLEKPDNVTLIRDYDPSLPELAHDPDQIEQ
VLLNITRNALQALGETGGTITLRTRTAFQVTLHGMRYRLAARIDIEDDGPGVPTQLQDTVFYPMVSGREGGTGLGLSIAR
NLIDQHSGKIEFNSWPGHTEFSVYLPIRQ

Sequences:

>Translated_349_residues
MATGTLPDAGQILNTLINSILLLDDDLAIHYANPAAQQLLAQSSRKLFGTPLPDLLGYFSLNIVLMRESLQAGQGFTDNE
VTLVVDGRAHILSLTAQSLAEGFILLELAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLAKALP
DPALLEYTQVIIEQADRLRNLVDRLLGPQRPGQHITQSIHQVAERVCQLVSLEKPDNVTLIRDYDPSLPELAHDPDQIEQ
VLLNITRNALQALGETGGTITLRTRTAFQVTLHGMRYRLAARIDIEDDGPGVPTQLQDTVFYPMVSGREGGTGLGLSIAR
NLIDQHSGKIEFNSWPGHTEFSVYLPIRQ
>Mature_348_residues
ATGTLPDAGQILNTLINSILLLDDDLAIHYANPAAQQLLAQSSRKLFGTPLPDLLGYFSLNIVLMRESLQAGQGFTDNEV
TLVVDGRAHILSLTAQSLAEGFILLELAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLAKALPD
PALLEYTQVIIEQADRLRNLVDRLLGPQRPGQHITQSIHQVAERVCQLVSLEKPDNVTLIRDYDPSLPELAHDPDQIEQV
LLNITRNALQALGETGGTITLRTRTAFQVTLHGMRYRLAARIDIEDDGPGVPTQLQDTVFYPMVSGREGGTGLGLSIARN
LIDQHSGKIEFNSWPGHTEFSVYLPIRQ

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: COG3852

COG function: function code T; Signal transduction histidine kinase, nitrogen specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=349, Percent_Identity=86.5329512893983, Blast_Score=618, Evalue=1e-178,
Organism=Escherichia coli, GI1788549, Length=355, Percent_Identity=27.6056338028169, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=31.3807531380753, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI87081816, Length=278, Percent_Identity=30.9352517985612, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=25.1063829787234, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790346, Length=248, Percent_Identity=27.0161290322581, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786600, Length=242, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=29.5652173913043, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38346; Mature: 38215

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGTLPDAGQILNTLINSILLLDDDLAIHYANPAAQQLLAQSSRKLFGTPLPDLLGYFS
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNIVLMRESLQAGQGFTDNEVTLVVDGRAHILSLTAQSLAEGFILLELAPMDNQRRLSQE
HHHHEEEHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
QLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLAKALPDPALLEYTQVIIEQADRLRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVDRLLGPQRPGQHITQSIHQVAERVCQLVSLEKPDNVTLIRDYDPSLPELAHDPDQIEQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHCCCHHHHHH
VLLNITRNALQALGETGGTITLRTRTAFQVTLHGMRYRLAARIDIEDDGPGVPTQLQDTV
HHHHHHHHHHHHHHCCCCEEEEEECEEEEEEHHHHEEEEEEEEEECCCCCCCCCCHHHHE
FYPMVSGREGGTGLGLSIARNLIDQHSGKIEFNSWPGHTEFSVYLPIRQ
EEEEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCC
>Mature Secondary Structure 
ATGTLPDAGQILNTLINSILLLDDDLAIHYANPAAQQLLAQSSRKLFGTPLPDLLGYFS
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNIVLMRESLQAGQGFTDNEVTLVVDGRAHILSLTAQSLAEGFILLELAPMDNQRRLSQE
HHHHEEEHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
QLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLAKALPDPALLEYTQVIIEQADRLRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVDRLLGPQRPGQHITQSIHQVAERVCQLVSLEKPDNVTLIRDYDPSLPELAHDPDQIEQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHCCCHHHHHH
VLLNITRNALQALGETGGTITLRTRTAFQVTLHGMRYRLAARIDIEDDGPGVPTQLQDTV
HHHHHHHHHHHHHHCCCCEEEEEECEEEEEEHHHHEEEEEEEEEECCCCCCCCCCHHHHE
FYPMVSGREGGTGLGLSIARNLIDQHSGKIEFNSWPGHTEFSVYLPIRQ
EEEEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]