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The map label for this gene is intZ [H]

Identifier: 170026369

GI number: 170026369

Start: 4592498

End: 4593766

Strand: Direct

Name: intZ [H]

Synonym: YPK_4162

Alternate gene names: 170026369

Gene position: 4592498-4593766 (Clockwise)

Preceding gene: 170026368

Following gene: 170026370

Centisome position: 97.93

GC content: 50.67

Gene sequence:

>1269_bases
ATGCCAAAATTTACAGATATGCAGATCCGCGCATGGATAAAGGCCGGAGAGCGATTCGAAGGCCGTGCAGATGGCAACGG
GCTATATCTGCGATACAGAGACGCAGACAGATCACCAACCTGGCGATTCCGTTATAAGTTCGCCGGTAAGTCACGCGCCA
TGTTAATTGGCTCATACGCTGAATTGTCCCTATCAAAAGCCAGAGAGACGGTCAAAGCGTTATCAGCTCGAGTATCCCTG
GGCTATGACGTTGCCGGAGAGAAGCAGGAGCGGAAAGCCGAAGCGCTAGCGAAGATGGAAACCGAAAAGAACGCTATGCG
GGTTTCAGGGCTTGCCGCTGAATACTTCGAACGCCAGATCTTGCCCCGCTGGAAGCACCCAGACATTTTGCGCCGCCGTA
TCGACAAAGATATAAACCCGCATATTGGCAGCATGAGGGTGGAGGACGTAAAGCCACGTCACATTGACGACATGCTAAAA
GCCATTGTTGACCGTGGAGCACCAACTATAGCCACGGACGTTCTACGCTGGACTCGTCGCATATTCGATTACGGTATCAA
GCGCCACGCATTAGAAGTCAATCCTTGCTCAGCCTTTGAGGTATCCGACGCTGGCGGAAAGGAAGTGAGCCGCGATCGCT
GGCTAACTCGTGATGAATTAATCCGGTTATTTCAGGCTATGCGAACGGCTAAAGGGTTCAGTCGCCAGAATGAAATCACG
TTTAAGCTGCTATTGGCCTTGTGCGTCCGAAAGATGGAGCTATGCGCCGCCCGTTGGGAAGAATTCGACCTCGACGCTGC
TATATGGCATTTGCCAGCAGAGCGTAGTAAAAATGGCGATGCTATCGATATTCCATTACCACCACCAGCGGCTGAGTGGC
TTAGAGAGCTTCATACATTTTCATGCAACAGCGCATGGGTACTGCCAGCCAGAAAAATGCAAAACAGGATGATTCCCCAC
ATCCAAGAAAGCACCTTACCCGTAGCATTAGCAAAAGTACGGGCTGAAATGCCGGATATTGAAAACGTTACTATTCATGA
TTTCAGACGCACTGCTCGCACACACTTAGCGGCGCTTGGAGTTGATCCGGTGGTAGCTGAACGTTGTCTGAATCACCGCA
TAAAGGGCGTTGAGGGCATTTATAACCGACACCAATATTTTGATGAGCGTAAGGCAGCACTGACACAGTGGGCTGCGTTG
CTGGTGGCCCTAGAGCGTGGCGAAGAATACAACGTAACTCCGATTAAAAAGCGGAAGGTGACAATATGA

Upstream 100 bases:

>100_bases
TCACAATAGCGCATGATTAGCGTGTACCCAAAGGTGTACCCAATGAGTTTCTCGCACATCACTTTGGGTACACTCCCTAT
TCAATGCTCAGGTAGCCGCG

Downstream 100 bases:

>100_bases
GATTATTAACTGAAAACATGTTTCAACGATTAACTACTCAACGCCTTGTCAGCATTAGCGAGGTGGTTAATTCGCTTTAT
GGAATAAACCCAAACACAAA

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MPKFTDMQIRAWIKAGERFEGRADGNGLYLRYRDADRSPTWRFRYKFAGKSRAMLIGSYAELSLSKARETVKALSARVSL
GYDVAGEKQERKAEALAKMETEKNAMRVSGLAAEYFERQILPRWKHPDILRRRIDKDINPHIGSMRVEDVKPRHIDDMLK
AIVDRGAPTIATDVLRWTRRIFDYGIKRHALEVNPCSAFEVSDAGGKEVSRDRWLTRDELIRLFQAMRTAKGFSRQNEIT
FKLLLALCVRKMELCAARWEEFDLDAAIWHLPAERSKNGDAIDIPLPPPAAEWLRELHTFSCNSAWVLPARKMQNRMIPH
IQESTLPVALAKVRAEMPDIENVTIHDFRRTARTHLAALGVDPVVAERCLNHRIKGVEGIYNRHQYFDERKAALTQWAAL
LVALERGEEYNVTPIKKRKVTI

Sequences:

>Translated_422_residues
MPKFTDMQIRAWIKAGERFEGRADGNGLYLRYRDADRSPTWRFRYKFAGKSRAMLIGSYAELSLSKARETVKALSARVSL
GYDVAGEKQERKAEALAKMETEKNAMRVSGLAAEYFERQILPRWKHPDILRRRIDKDINPHIGSMRVEDVKPRHIDDMLK
AIVDRGAPTIATDVLRWTRRIFDYGIKRHALEVNPCSAFEVSDAGGKEVSRDRWLTRDELIRLFQAMRTAKGFSRQNEIT
FKLLLALCVRKMELCAARWEEFDLDAAIWHLPAERSKNGDAIDIPLPPPAAEWLRELHTFSCNSAWVLPARKMQNRMIPH
IQESTLPVALAKVRAEMPDIENVTIHDFRRTARTHLAALGVDPVVAERCLNHRIKGVEGIYNRHQYFDERKAALTQWAAL
LVALERGEEYNVTPIKKRKVTI
>Mature_421_residues
PKFTDMQIRAWIKAGERFEGRADGNGLYLRYRDADRSPTWRFRYKFAGKSRAMLIGSYAELSLSKARETVKALSARVSLG
YDVAGEKQERKAEALAKMETEKNAMRVSGLAAEYFERQILPRWKHPDILRRRIDKDINPHIGSMRVEDVKPRHIDDMLKA
IVDRGAPTIATDVLRWTRRIFDYGIKRHALEVNPCSAFEVSDAGGKEVSRDRWLTRDELIRLFQAMRTAKGFSRQNEITF
KLLLALCVRKMELCAARWEEFDLDAAIWHLPAERSKNGDAIDIPLPPPAAEWLRELHTFSCNSAWVLPARKMQNRMIPHI
QESTLPVALAKVRAEMPDIENVTIHDFRRTARTHLAALGVDPVVAERCLNHRIKGVEGIYNRHQYFDERKAALTQWAALL
VALERGEEYNVTPIKKRKVTI

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=398, Percent_Identity=25.8793969849246, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788974, Length=413, Percent_Identity=27.1186440677966, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788690, Length=387, Percent_Identity=26.8733850129199, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 48612; Mature: 48481

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKFTDMQIRAWIKAGERFEGRADGNGLYLRYRDADRSPTWRFRYKFAGKSRAMLIGSYA
CCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEEEECHH
ELSLSKARETVKALSARVSLGYDVAGEKQERKAEALAKMETEKNAMRVSGLAAEYFERQI
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPRWKHPDILRRRIDKDINPHIGSMRVEDVKPRHIDDMLKAIVDRGAPTIATDVLRWTRR
CCCCCCHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
IFDYGIKRHALEVNPCSAFEVSDAGGKEVSRDRWLTRDELIRLFQAMRTAKGFSRQNEIT
HHHHHHHHCEEECCCCCCEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHH
FKLLLALCVRKMELCAARWEEFDLDAAIWHLPAERSKNGDAIDIPLPPPAAEWLRELHTF
HHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHC
SCNSAWVLPARKMQNRMIPHIQESTLPVALAKVRAEMPDIENVTIHDFRRTARTHLAALG
CCCCEEECCHHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
VDPVVAERCLNHRIKGVEGIYNRHQYFDERKAALTQWAALLVALERGEEYNVTPIKKRKV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TI
CC
>Mature Secondary Structure 
PKFTDMQIRAWIKAGERFEGRADGNGLYLRYRDADRSPTWRFRYKFAGKSRAMLIGSYA
CCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEEEECHH
ELSLSKARETVKALSARVSLGYDVAGEKQERKAEALAKMETEKNAMRVSGLAAEYFERQI
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPRWKHPDILRRRIDKDINPHIGSMRVEDVKPRHIDDMLKAIVDRGAPTIATDVLRWTRR
CCCCCCHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
IFDYGIKRHALEVNPCSAFEVSDAGGKEVSRDRWLTRDELIRLFQAMRTAKGFSRQNEIT
HHHHHHHHCEEECCCCCCEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHH
FKLLLALCVRKMELCAARWEEFDLDAAIWHLPAERSKNGDAIDIPLPPPAAEWLRELHTF
HHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHC
SCNSAWVLPARKMQNRMIPHIQESTLPVALAKVRAEMPDIENVTIHDFRRTARTHLAALG
CCCCEEECCHHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
VDPVVAERCLNHRIKGVEGIYNRHQYFDERKAALTQWAALLVALERGEEYNVTPIKKRKV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TI
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]