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The map label for this gene is slmA

Identifier: 170026365

GI number: 170026365

Start: 4589059

End: 4589655

Strand: Direct

Name: slmA

Synonym: YPK_4158

Alternate gene names: 170026365

Gene position: 4589059-4589655 (Clockwise)

Preceding gene: 170026364

Following gene: 170026368

Centisome position: 97.86

GC content: 48.07

Gene sequence:

>597_bases
ATGGCAGAAAAAGAAAATACGAAAAGGAACAGGCGCGAGGAAATATTGCAGGCTTTAGCGCAGATGCTGGAATCCAGCGA
CGGCAGCCAACGCATTACTACCGCGAAACTCGCCGCTAATGTGGGGGTTTCTGAAGCAGCGCTTTATCGGCATTTCCCCA
GTAAAACGCGGATGTTTGATAGCCTGATCGAGTTTATTGAAGATAGTCTGATGTCCCGCATTAATTTGATTCTACAAGAT
GAAAAAGAGACGTTTAATCGCCTCCGCTTAATCCTGCTGTTGGTATTAGGGTTTGCAGAGCGCAACCCTGGGCTGACCCG
AATCATGACCGGGCATGCGCTCATGTTTGAGCAGGATCGCTTACAAGGGCGGATTAACCAGCTATTTGAACGAATTGAAA
TGCAGTTACGCCAAGTCCTTCGTGAGAAAAAGCTGCGTGATGGACAAGGCTTTATCCATGATGAAGCGTTACTGGCCACC
CAGTTGTTGGCATTTTGCGAAGGGATGCTTTCACGCTTCGTTCGTTCTGAATTCCGTTACTGCCCAACACAAGAGTTTGA
TTCCCGCTGGCCATTGATTGTCGCCCAGTTGCAATAA

Upstream 100 bases:

>100_bases
GTAAAAAAGCTATCACATAAGCCGCCTGGGCATTGTTCCCAGAGCGGCCGGTGTTTGGGTTTTTGTTATTAAGTCATTTT
TAGCAAGGGTCTACTCGGAC

Downstream 100 bases:

>100_bases
AACCCAGGATCAACTTTCTCTTTCCTCTTCTCCGTAAGACATAGAGAGAACAGCGAATCAAGCTACGCAAAAAGGGCAAA
CGGCCCTCTTGGCGTAGCTT

Product: nucleoid occlusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MAEKENTKRNRREEILQALAQMLESSDGSQRITTAKLAANVGVSEAALYRHFPSKTRMFDSLIEFIEDSLMSRINLILQD
EKETFNRLRLILLLVLGFAERNPGLTRIMTGHALMFEQDRLQGRINQLFERIEMQLRQVLREKKLRDGQGFIHDEALLAT
QLLAFCEGMLSRFVRSEFRYCPTQEFDSRWPLIVAQLQ

Sequences:

>Translated_198_residues
MAEKENTKRNRREEILQALAQMLESSDGSQRITTAKLAANVGVSEAALYRHFPSKTRMFDSLIEFIEDSLMSRINLILQD
EKETFNRLRLILLLVLGFAERNPGLTRIMTGHALMFEQDRLQGRINQLFERIEMQLRQVLREKKLRDGQGFIHDEALLAT
QLLAFCEGMLSRFVRSEFRYCPTQEFDSRWPLIVAQLQ
>Mature_197_residues
AEKENTKRNRREEILQALAQMLESSDGSQRITTAKLAANVGVSEAALYRHFPSKTRMFDSLIEFIEDSLMSRINLILQDE
KETFNRLRLILLLVLGFAERNPGLTRIMTGHALMFEQDRLQGRINQLFERIEMQLRQVLREKKLRDGQGFIHDEALLATQ
LLAFCEGMLSRFVRSEFRYCPTQEFDSRWPLIVAQLQ

Specific function: Required for nucleoid occlusion (NO) phenomenon, which cooperates in the proper positioning of the ftsZ/septal ring at midcell during cell division. Acts as a DNA-associated division inhibitor directly involved in preventing Z ring assembly on portions of

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm, nucleoid

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI87082302, Length=198, Percent_Identity=83.3333333333333, Blast_Score=325, Evalue=1e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SLMA_YERP3 (A7FCT1)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001399059.1
- ProteinModelPortal:   A7FCT1
- STRING:   A7FCT1
- GeneID:   5387780
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_0058
- eggNOG:   COG1309
- HOGENOM:   HBG297015
- OMA:   RSEFRYR
- ProtClustDB:   PRK09480
- BioCyc:   YPSE349747:YPSIP31758_0058-MONOMER
- GO:   GO:0005737
- GO:   GO:0009295
- HAMAP:   MF_01839
- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647
- Gene3D:   G3DSA:1.10.357.10

Pfam domain/function: PF00440 TetR_N; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 23107; Mature: 22976

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS01081 HTH_TETR_1; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKENTKRNRREEILQALAQMLESSDGSQRITTAKLAANVGVSEAALYRHFPSKTRMFD
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHH
SLIEFIEDSLMSRINLILQDEKETFNRLRLILLLVLGFAERNPGLTRIMTGHALMFEQDR
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LQGRINQLFERIEMQLRQVLREKKLRDGQGFIHDEALLATQLLAFCEGMLSRFVRSEFRY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
CPTQEFDSRWPLIVAQLQ
CCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
AEKENTKRNRREEILQALAQMLESSDGSQRITTAKLAANVGVSEAALYRHFPSKTRMFD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHH
SLIEFIEDSLMSRINLILQDEKETFNRLRLILLLVLGFAERNPGLTRIMTGHALMFEQDR
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LQGRINQLFERIEMQLRQVLREKKLRDGQGFIHDEALLATQLLAFCEGMLSRFVRSEFRY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
CPTQEFDSRWPLIVAQLQ
CCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA