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The map label for this gene is mchE [H]

Identifier: 170026316

GI number: 170026316

Start: 4540724

End: 4542016

Strand: Direct

Name: mchE [H]

Synonym: YPK_4109

Alternate gene names: 170026316

Gene position: 4540724-4542016 (Clockwise)

Preceding gene: 170026313

Following gene: 170026317

Centisome position: 96.83

GC content: 39.21

Gene sequence:

>1293_bases
ATGAGCAGCAATCAGATATTCCGCCGGGACGCGGTAGAGTATATTAGAACAAAATGGTTGGGGAAGGCGCTGTTAACTTC
GGGTTATTCCACAACGTTCATAGCTGCTTTATGTGCTATCTTTTTGGTGTTATTAATTACTCTTATCATTTATGGAACAT
ACACCCGTAGAATAAACGTTAATGGTGAGGTTATTTCTCAGCCTCACCCCATAAACATTTTTTCTCCCCAACAAGGATTC
ATTACCAAAAAATGGGTAGAAGTGGGTGATATTGTCCGTAAAGGTCAGCACTTATATCAAATTGATGTCAGTCGAACGAC
CTTTTCAGGTAATGTTAGCCTTAACTCTTTAGAAGCAATAAATAACCAACTTTCTCAAATTGATAGCATCATCAATAATA
CACAGAAAAATAAAGAACTTACGCTACTTAATTTACGTCAGCAGCTCGCACAATACCAAAAGGCACATAAGAAATCCCAA
GAGCTGGTCGATAACGCAGGCAAAGGAATGGATGATATGCGGCGTACAATGGCCAGTTATGGTACTTACCAACGTCAGGG
TCTAATTACTAAAGATCAATTAACCAATCAGCGTTCCCTCTTTTATCAACAACAGAATGCCTTTCAAAGCCTGAATACTC
AACTGATACAAGAAAGCTTACAGATAGCAAAACTTGAAAGTGAAATCTCTACGCGAGCATCAGATTTTGATAATGATATC
TCTCAGTATTTATTTCAAAAAGGTGATTTAAAGCGTCAATTGGCTGAAGTTGATGCGAGTGGCATGTTACTCATTAATTC
GCCAAGCGATGGCAAGATTGAAAATATGAGTGTGACCCAAGGACAGATGGTCAACGTAAATGACAGTTTGGTCCAATTGA
CGCCTTCTGATAATCCCTATTATTGTCTTGTGCTTTGGGTACCAAACAATAGCGTCCCTTATATAAATACTGGAGACAAA
GTCAATATACGCTATGACGCTTTCCCCTTTGAAAAGTTTGGTCAATTTCCTGGGCGTATAATCTCTATCTCTAATGTCCC
CGTTTCACAACAAGAAATAGCCTCATACAACATTGCACCGCGGCTCCCGAACGGTGGACTCATTGAGCCTTACTATAAAG
TCATCGTGGCACTAGACGATATTCATTTTCGTTATCAGTCTAAACCTTTAATGCTATCCAATGGCCTTAAAGCTAATGTC
ACGTTATTCCTTGAAAAAAGGCCTCTTTATCAATGGATGCTATCTCCATTCTATGACATCAAGAAAAGTGTAACGGGGCC
TGTAAATGAATGA

Upstream 100 bases:

>100_bases
ATTAAATATACCGAAATAGAGTTACGTGAAAATGATTCAATTAAACCTTCTATTTTTTGTGATATGTTGATTTGAAATGA
TGGGTATAACGGAGCGAGGA

Downstream 100 bases:

>100_bases
TACGCATTTTAACGAGATAAAAAACCGTCTGAATTTTAGCTTTCGTCGTAAAGTCCCACAGGTGCTTCAAACCGAAGCAG
CAGAATGCGGACTTGCCTGT

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MSSNQIFRRDAVEYIRTKWLGKALLTSGYSTTFIAALCAIFLVLLITLIIYGTYTRRINVNGEVISQPHPINIFSPQQGF
ITKKWVEVGDIVRKGQHLYQIDVSRTTFSGNVSLNSLEAINNQLSQIDSIINNTQKNKELTLLNLRQQLAQYQKAHKKSQ
ELVDNAGKGMDDMRRTMASYGTYQRQGLITKDQLTNQRSLFYQQQNAFQSLNTQLIQESLQIAKLESEISTRASDFDNDI
SQYLFQKGDLKRQLAEVDASGMLLINSPSDGKIENMSVTQGQMVNVNDSLVQLTPSDNPYYCLVLWVPNNSVPYINTGDK
VNIRYDAFPFEKFGQFPGRIISISNVPVSQQEIASYNIAPRLPNGGLIEPYYKVIVALDDIHFRYQSKPLMLSNGLKANV
TLFLEKRPLYQWMLSPFYDIKKSVTGPVNE

Sequences:

>Translated_430_residues
MSSNQIFRRDAVEYIRTKWLGKALLTSGYSTTFIAALCAIFLVLLITLIIYGTYTRRINVNGEVISQPHPINIFSPQQGF
ITKKWVEVGDIVRKGQHLYQIDVSRTTFSGNVSLNSLEAINNQLSQIDSIINNTQKNKELTLLNLRQQLAQYQKAHKKSQ
ELVDNAGKGMDDMRRTMASYGTYQRQGLITKDQLTNQRSLFYQQQNAFQSLNTQLIQESLQIAKLESEISTRASDFDNDI
SQYLFQKGDLKRQLAEVDASGMLLINSPSDGKIENMSVTQGQMVNVNDSLVQLTPSDNPYYCLVLWVPNNSVPYINTGDK
VNIRYDAFPFEKFGQFPGRIISISNVPVSQQEIASYNIAPRLPNGGLIEPYYKVIVALDDIHFRYQSKPLMLSNGLKANV
TLFLEKRPLYQWMLSPFYDIKKSVTGPVNE
>Mature_429_residues
SSNQIFRRDAVEYIRTKWLGKALLTSGYSTTFIAALCAIFLVLLITLIIYGTYTRRINVNGEVISQPHPINIFSPQQGFI
TKKWVEVGDIVRKGQHLYQIDVSRTTFSGNVSLNSLEAINNQLSQIDSIINNTQKNKELTLLNLRQQLAQYQKAHKKSQE
LVDNAGKGMDDMRRTMASYGTYQRQGLITKDQLTNQRSLFYQQQNAFQSLNTQLIQESLQIAKLESEISTRASDFDNDIS
QYLFQKGDLKRQLAEVDASGMLLINSPSDGKIENMSVTQGQMVNVNDSLVQLTPSDNPYYCLVLWVPNNSVPYINTGDKV
NIRYDAFPFEKFGQFPGRIISISNVPVSQQEIASYNIAPRLPNGGLIEPYYKVIVALDDIHFRYQSKPLMLSNGLKANVT
LFLEKRPLYQWMLSPFYDIKKSVTGPVNE

Specific function: Probably involved, in conjunction with mchF, in the secretion of microcin H47 [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 48827; Mature: 48696

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNQIFRRDAVEYIRTKWLGKALLTSGYSTTFIAALCAIFLVLLITLIIYGTYTRRINV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
NGEVISQPHPINIFSPQQGFITKKWVEVGDIVRKGQHLYQIDVSRTTFSGNVSLNSLEAI
CCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECEEEEECCCCHHHHHHH
NNQLSQIDSIINNTQKNKELTLLNLRQQLAQYQKAHKKSQELVDNAGKGMDDMRRTMASY
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GTYQRQGLITKDQLTNQRSLFYQQQNAFQSLNTQLIQESLQIAKLESEISTRASDFDNDI
CCHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQYLFQKGDLKRQLAEVDASGMLLINSPSDGKIENMSVTQGQMVNVNDSLVQLTPSDNPY
HHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCEECEEECCCEEEECCCCEEEECCCCCCE
YCLVLWVPNNSVPYINTGDKVNIRYDAFPFEKFGQFPGRIISISNVPVSQQEIASYNIAP
EEEEEEECCCCCCEEECCCEEEEEEECCCHHHHCCCCCEEEEECCCCCCHHHHHHCCCCC
RLPNGGLIEPYYKVIVALDDIHFRYQSKPLMLSNGLKANVTLFLEKRPLYQWMLSPFYDI
CCCCCCCCCHHHHHHEEEEHHEEEECCCCEEEECCCCEEEEEEEECCHHHHHHHHHHHHH
KKSVTGPVNE
HHHCCCCCCC
>Mature Secondary Structure 
SSNQIFRRDAVEYIRTKWLGKALLTSGYSTTFIAALCAIFLVLLITLIIYGTYTRRINV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
NGEVISQPHPINIFSPQQGFITKKWVEVGDIVRKGQHLYQIDVSRTTFSGNVSLNSLEAI
CCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECEEEEECCCCHHHHHHH
NNQLSQIDSIINNTQKNKELTLLNLRQQLAQYQKAHKKSQELVDNAGKGMDDMRRTMASY
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GTYQRQGLITKDQLTNQRSLFYQQQNAFQSLNTQLIQESLQIAKLESEISTRASDFDNDI
CCHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQYLFQKGDLKRQLAEVDASGMLLINSPSDGKIENMSVTQGQMVNVNDSLVQLTPSDNPY
HHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCEECEEECCCEEEECCCCEEEECCCCCCE
YCLVLWVPNNSVPYINTGDKVNIRYDAFPFEKFGQFPGRIISISNVPVSQQEIASYNIAP
EEEEEEECCCCCCEEECCCEEEEEEECCCHHHHCCCCCEEEEECCCCCCHHHHHHCCCCC
RLPNGGLIEPYYKVIVALDDIHFRYQSKPLMLSNGLKANVTLFLEKRPLYQWMLSPFYDI
CCCCCCCCCHHHHHHEEEEHHEEEECCCCEEEECCCCEEEEEEEECCHHHHHHHHHHHHH
KKSVTGPVNE
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11181394 [H]