Click here to switch to the map view.

The map label for this gene is col [H]

Identifier: 170026258

GI number: 170026258

Start: 4466408

End: 4466659

Strand: Reverse

Name: col [H]

Synonym: YPK_4048

Alternate gene names: 170026258

Gene position: 4466659-4466408 (Counterclockwise)

Preceding gene: 170026259

Following gene: 170026257

Centisome position: 95.25

GC content: 40.87

Gene sequence:

>252_bases
ATGACTTTTTGGCGCGAGGTGGCGAATGAACCTGAGTTGGTTGGTCAGTTTAAGCCTAACAATGTTTCATTGATGAAAAA
GGGTTTGTCCCCACATCCTGTATTGTCAGAAAAGGTTGGTGGGAGAGATACATTTGAGATCCATCATGTTAATTCGATCA
AAAGTGGTGGAGCAGTTTATGATGTGGATAATTTACGAGTAGCAACGCCAAAACGCCACATTGAAATTCATTCAAGACGT
GGAGGAAAATAA

Upstream 100 bases:

>100_bases
CAGCTAGTTAACACTTAATAATATGACTGTCAGCTCTAATTTTATTATCCAGACTAATGGTGGGTTATTATTTAAATAGT
AAAAAATATTCAGTTATAAT

Downstream 100 bases:

>100_bases
AATGGAACTTAAAGAGAAGTATGAGGATTATACAGAGCATGAATTTTTAGAGTTTATTAGAAATATTTGTGAGGTGAATA
CTGATAGTCAATCTTTGCAT

Product: HNH endonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 83; Mature: 82

Protein sequence:

>83_residues
MTFWREVANEPELVGQFKPNNVSLMKKGLSPHPVLSEKVGGRDTFEIHHVNSIKSGGAVYDVDNLRVATPKRHIEIHSRR
GGK

Sequences:

>Translated_83_residues
MTFWREVANEPELVGQFKPNNVSLMKKGLSPHPVLSEKVGGRDTFEIHHVNSIKSGGAVYDVDNLRVATPKRHIEIHSRR
GGK
>Mature_82_residues
TFWREVANEPELVGQFKPNNVSLMKKGLSPHPVLSEKVGGRDTFEIHHVNSIKSGGAVYDVDNLRVATPKRHIEIHSRRG
GK

Specific function: Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the colicin/pyosin nuclease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002711
- InterPro:   IPR003615 [H]

Pfam domain/function: PF01844 HNH [H]

EC number: NA

Molecular weight: Translated: 9302; Mature: 9171

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFWREVANEPELVGQFKPNNVSLMKKGLSPHPVLSEKVGGRDTFEIHHVNSIKSGGAVY
CCCHHHHCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEE
DVDNLRVATPKRHIEIHSRRGGK
ECCCEEEECCCCEEEEECCCCCC
>Mature Secondary Structure 
TFWREVANEPELVGQFKPNNVSLMKKGLSPHPVLSEKVGGRDTFEIHHVNSIKSGGAVY
CCHHHHCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEE
DVDNLRVATPKRHIEIHSRRGGK
ECCCEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3323826; 3290201 [H]