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The map label for this gene is fimB [H]

Identifier: 170026256

GI number: 170026256

Start: 4464696

End: 4465514

Strand: Direct

Name: fimB [H]

Synonym: YPK_4046

Alternate gene names: 170026256

Gene position: 4464696-4465514 (Clockwise)

Preceding gene: 170026255

Following gene: 170026262

Centisome position: 95.21

GC content: 48.23

Gene sequence:

>819_bases
ATGCACATGCGCAAGTGGTTATCCGTGTCCAATAATATAATGCTTAGCCGTATCAACCGTAGGCTCCGTGGGTTGCTGCT
ACTCATGACCACCTGTCGTGTACTGACTCTCCCTGCGCTGACGATTGGCGTGCTGATAATGAGTGCGCTGGCAACGAGTG
CAGTGGCAAGTGTGATTGCAGAGAGAACACGTATTGTCTTCAGTGAAGGCAGTACAGAAGAGTCACTGCAACTGGTGAAC
AGCAATAGCTATCCGGTAGCGGTACAAGTTTGGGTGGATGACGGCAATTTGATGGCGACGCCTGATAAGGCTGTTTCACC
CATATTGGTGTTACCTCCGGTATTCCGGTTACAACCTCAGGCACAGCGTAGCCTGCGGTTGATCTTATCTGGTGGGAGTA
AATTACCTGCGGATAGGGAATCTGCATTCTGGCTAAATATTTACGAAATCCCGCCTAAGGCAACCCCCAAATCCGGTGAT
GAATCTTTTGTTACGCTGGCCCTACGGATGCAATATAAAGTCTTTTACCGCCCTAAAAACCTACCCGCGCCAGGAGATAT
TTTAGGCAAGGCATTAACCTTTAGCCTCGAGCGTAACGGCGACAGTGCGCTGATTAAGGTTAACAATCCAACCCCTTACT
ATGCATCCTTCGCTGCTTTGACCATCGGTTCAGCCGAAGGCCCTCCGGAAATGGTGGCCCCGTTCTCTCAATTAGATTTT
CCACTAAACCGAGCGCCAATTAGCGACAACAAAACCGTCAATTTTGATTTAATTGATGATTTAGGCAACCGAAACTCTTT
TAGCCATGAGTTGAAATAA

Upstream 100 bases:

>100_bases
GAAACCACAGGCAGCGTAGATGGGGGGAACAGTTACACCGAAACTTTCCGTGCTGAGTTAAGCAAAATAAGCGGGCAAAC
AGTGACCGCCGGAGCAGTGA

Downstream 100 bases:

>100_bases
AGTGCGCTGCTGGGAATGGCAGTTTGGGGGCGAGTAGCGCACAGACACTGGAAGCTTATTACGGTTTGAATATAACTCAT
AATTTCTCTCCTTGTTATAT

Product: pili assembly chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MHMRKWLSVSNNIMLSRINRRLRGLLLLMTTCRVLTLPALTIGVLIMSALATSAVASVIAERTRIVFSEGSTEESLQLVN
SNSYPVAVQVWVDDGNLMATPDKAVSPILVLPPVFRLQPQAQRSLRLILSGGSKLPADRESAFWLNIYEIPPKATPKSGD
ESFVTLALRMQYKVFYRPKNLPAPGDILGKALTFSLERNGDSALIKVNNPTPYYASFAALTIGSAEGPPEMVAPFSQLDF
PLNRAPISDNKTVNFDLIDDLGNRNSFSHELK

Sequences:

>Translated_272_residues
MHMRKWLSVSNNIMLSRINRRLRGLLLLMTTCRVLTLPALTIGVLIMSALATSAVASVIAERTRIVFSEGSTEESLQLVN
SNSYPVAVQVWVDDGNLMATPDKAVSPILVLPPVFRLQPQAQRSLRLILSGGSKLPADRESAFWLNIYEIPPKATPKSGD
ESFVTLALRMQYKVFYRPKNLPAPGDILGKALTFSLERNGDSALIKVNNPTPYYASFAALTIGSAEGPPEMVAPFSQLDF
PLNRAPISDNKTVNFDLIDDLGNRNSFSHELK
>Mature_272_residues
MHMRKWLSVSNNIMLSRINRRLRGLLLLMTTCRVLTLPALTIGVLIMSALATSAVASVIAERTRIVFSEGSTEESLQLVN
SNSYPVAVQVWVDDGNLMATPDKAVSPILVLPPVFRLQPQAQRSLRLILSGGSKLPADRESAFWLNIYEIPPKATPKSGD
ESFVTLALRMQYKVFYRPKNLPAPGDILGKALTFSLERNGDSALIKVNNPTPYYASFAALTIGSAEGPPEMVAPFSQLDF
PLNRAPISDNKTVNFDLIDDLGNRNSFSHELK

Specific function: Required for the biogenesis of the filamentous hemagglutinin and the fimbria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1786333, Length=220, Percent_Identity=32.2727272727273, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1789532, Length=229, Percent_Identity=29.6943231441048, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87082203, Length=238, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787171, Length=238, Percent_Identity=30.2521008403361, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790771, Length=227, Percent_Identity=28.1938325991189, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786936, Length=201, Percent_Identity=30.3482587064677, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788677, Length=161, Percent_Identity=36.6459627329193, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786743, Length=239, Percent_Identity=29.2887029288703, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788428, Length=223, Percent_Identity=26.0089686098655, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 29941; Mature: 29941

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMRKWLSVSNNIMLSRINRRLRGLLLLMTTCRVLTLPALTIGVLIMSALATSAVASVIA
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERTRIVFSEGSTEESLQLVNSNSYPVAVQVWVDDGNLMATPDKAVSPILVLPPVFRLQPQ
HHHEEEEECCCCHHHHEEECCCCCCEEEEEEEECCCEEECCHHHCCCEEECCCCHHCCCH
AQRSLRLILSGGSKLPADRESAFWLNIYEIPPKATPKSGDESFVTLALRMQYKVFYRPKN
HHHCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEEEEECCCC
LPAPGDILGKALTFSLERNGDSALIKVNNPTPYYASFAALTIGSAEGPPEMVAPFSQLDF
CCCCHHHHHHEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCCHHHHCCHHHCCC
PLNRAPISDNKTVNFDLIDDLGNRNSFSHELK
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MHMRKWLSVSNNIMLSRINRRLRGLLLLMTTCRVLTLPALTIGVLIMSALATSAVASVIA
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERTRIVFSEGSTEESLQLVNSNSYPVAVQVWVDDGNLMATPDKAVSPILVLPPVFRLQPQ
HHHEEEEECCCCHHHHEEECCCCCCEEEEEEEECCCEEECCHHHCCCEEECCCCHHCCCH
AQRSLRLILSGGSKLPADRESAFWLNIYEIPPKATPKSGDESFVTLALRMQYKVFYRPKN
HHHCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEEEEECCCC
LPAPGDILGKALTFSLERNGDSALIKVNNPTPYYASFAALTIGSAEGPPEMVAPFSQLDF
CCCCHHHHHHEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCCHHHHCCHHHCCC
PLNRAPISDNKTVNFDLIDDLGNRNSFSHELK
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1360139; 1354611; 12910271 [H]