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The map label for this gene is ftsY [H]

Identifier: 170026190

GI number: 170026190

Start: 4388685

End: 4390256

Strand: Reverse

Name: ftsY [H]

Synonym: YPK_3979

Alternate gene names: 170026190

Gene position: 4390256-4388685 (Counterclockwise)

Preceding gene: 170026193

Following gene: 170026189

Centisome position: 93.62

GC content: 48.73

Gene sequence:

>1572_bases
ATGGCAAAAGAAAAAAAACGTGGATTTTTTTCCTGGCTGGGTCTTGGCCGTCAGAGTGAAGAACCAGCAGCAGAGCCGCT
GGCGACTGAAAAAGAAGGCGTTACAGAGCAAGAAGACGTTATTGAACAAACCGGCGTTATTGAGCAAACCGTTGAGCACG
TCATTAGTGAAAAAACGACTGAAGCTCCCGCGGAGAATGCCTTTATTGAGGTAGAACTGCGCGAGCAGGTCGCTGCGGTA
ATTCCTACTGAGCCGAATAACGCCATAATGAGTGAGGGCGTCCCTGACACTTTACCAGAGAGGGCGGTTGCCGAATCAGT
AGTTGCCGAATTAGTAGAGACCGGTGACAACGCGGCCATTGTTCATGATGAGATTATCGAGCCAATAACGCAGGTAACGG
AAGCTGGCGGTGAGCTCTCTTTAGTAAAACCTGGCATCGAGGGTGATACCACTGAACAGGGCGGCCCCACAGACAATCTG
CCAAAACGGTCGTTAACGGAAGACAACCTTATTATTGATGTTCCCACCCCGCAGGCGGTGGTAGAAGAATCGCGGGTTGA
CGCTGTTGAGCAACCTACCGAAACTTCTGAAGTTGAAGAAGTTGAAGAAAAAATTATCCCGGTAGCGGCTCAAGAACAAG
AGCGGCCAACCAAAGAAGGTTTCTTCGCGCGTTTAAAACGCAGCTTAATCAAGACTAAACAGAATCTTGGCTCCGGTTTT
ATGGGGCTGTTCAGCGGCAAAAAGATTGATGATGACTTGTTTGAAGAGCTGGAAGAACAGCTCCTGATCGCCGATGTTGG
TGTCGAAACAACCCGTAAAATCATTACTTCTCTGACAGAACATACCAGCCGTAAGCAGTTAAAAGATGCTGATGCGCTGT
ACGGCAAGCTCAAAGAGGAAATGTCTGAGATTCTGTCTAAAGTTGACAAGCCATTAGATGTTAGCGGCAAGAGTCCGTAT
GTCATTTTAATGGTTGGTGTTAATGGCGTGGGCAAAACCACCACTATTGGCAAACTGGCGCGCCAATTCCAGGCTGAAGG
TAAATCTGTCATGTTGGCGGCGGGTGATACATTCCGTGCCGCTGCCGTTGAGCAATTACAAGTTTGGGGTGAGCGTAACA
AGATTGCGGTTGTTGCACAGCATACCGGTGCAGATTCCGCTTCGGTTATTTTCGATGCGATTCAGGCGGCTAAAGCCCGT
GGTATTGATGTGCTGTTGGCCGATACCGCTGGGCGTTTACAAAATAAAGCCCACTTGATGGAAGAGCTGAAGAAGATTGT
CCGGGTAATGAAAAAACTGGACGGCGACGCCCCCCATGAGGTTATGCTGACACTGGATGCCAGTACCGGACAAAATGCGG
TGAGTCAGGCAAAACTGTTTAATGAAGCAGTGGGCCTGACCGGGATTACCCTAACTAAACTGGATGGTACCGCCAAAGGC
GGGGTGATTTTTGCCATTGCTGATCAGTTTGAGATCCCAATCCGTTATATCGGTGTCGGAGAAGGTATAGAAGATTTGCG
GCCATTTAAGGCTGACGAATTTATTGAGGCTCTTTTTGCCCGAGAGGATTAA

Upstream 100 bases:

>100_bases
CAGGAGAAAGTGATAGACTTGCACATTATTATTGTACCCAAGGCTATTATTGTACCCAAAGGTATAAGCCATGATTTAAC
CGCGAGGAGTGTAGTCGCAA

Downstream 100 bases:

>100_bases
TACGGATGATTCGCTTTGAACAGGTCAGTAAAGCTTATCTGGGGGGACGGCAGGCGCTGCAGGGGGTCGATTTTCATCTG
CGTCCTGCGGAAATGGCGTT

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 522

Protein sequence:

>523_residues
MAKEKKRGFFSWLGLGRQSEEPAAEPLATEKEGVTEQEDVIEQTGVIEQTVEHVISEKTTEAPAENAFIEVELREQVAAV
IPTEPNNAIMSEGVPDTLPERAVAESVVAELVETGDNAAIVHDEIIEPITQVTEAGGELSLVKPGIEGDTTEQGGPTDNL
PKRSLTEDNLIIDVPTPQAVVEESRVDAVEQPTETSEVEEVEEKIIPVAAQEQERPTKEGFFARLKRSLIKTKQNLGSGF
MGLFSGKKIDDDLFEELEEQLLIADVGVETTRKIITSLTEHTSRKQLKDADALYGKLKEEMSEILSKVDKPLDVSGKSPY
VILMVGVNGVGKTTTIGKLARQFQAEGKSVMLAAGDTFRAAAVEQLQVWGERNKIAVVAQHTGADSASVIFDAIQAAKAR
GIDVLLADTAGRLQNKAHLMEELKKIVRVMKKLDGDAPHEVMLTLDASTGQNAVSQAKLFNEAVGLTGITLTKLDGTAKG
GVIFAIADQFEIPIRYIGVGEGIEDLRPFKADEFIEALFARED

Sequences:

>Translated_523_residues
MAKEKKRGFFSWLGLGRQSEEPAAEPLATEKEGVTEQEDVIEQTGVIEQTVEHVISEKTTEAPAENAFIEVELREQVAAV
IPTEPNNAIMSEGVPDTLPERAVAESVVAELVETGDNAAIVHDEIIEPITQVTEAGGELSLVKPGIEGDTTEQGGPTDNL
PKRSLTEDNLIIDVPTPQAVVEESRVDAVEQPTETSEVEEVEEKIIPVAAQEQERPTKEGFFARLKRSLIKTKQNLGSGF
MGLFSGKKIDDDLFEELEEQLLIADVGVETTRKIITSLTEHTSRKQLKDADALYGKLKEEMSEILSKVDKPLDVSGKSPY
VILMVGVNGVGKTTTIGKLARQFQAEGKSVMLAAGDTFRAAAVEQLQVWGERNKIAVVAQHTGADSASVIFDAIQAAKAR
GIDVLLADTAGRLQNKAHLMEELKKIVRVMKKLDGDAPHEVMLTLDASTGQNAVSQAKLFNEAVGLTGITLTKLDGTAKG
GVIFAIADQFEIPIRYIGVGEGIEDLRPFKADEFIEALFARED
>Mature_522_residues
AKEKKRGFFSWLGLGRQSEEPAAEPLATEKEGVTEQEDVIEQTGVIEQTVEHVISEKTTEAPAENAFIEVELREQVAAVI
PTEPNNAIMSEGVPDTLPERAVAESVVAELVETGDNAAIVHDEIIEPITQVTEAGGELSLVKPGIEGDTTEQGGPTDNLP
KRSLTEDNLIIDVPTPQAVVEESRVDAVEQPTETSEVEEVEEKIIPVAAQEQERPTKEGFFARLKRSLIKTKQNLGSGFM
GLFSGKKIDDDLFEELEEQLLIADVGVETTRKIITSLTEHTSRKQLKDADALYGKLKEEMSEILSKVDKPLDVSGKSPYV
ILMVGVNGVGKTTTIGKLARQFQAEGKSVMLAAGDTFRAAAVEQLQVWGERNKIAVVAQHTGADSASVIFDAIQAAKARG
IDVLLADTAGRLQNKAHLMEELKKIVRVMKKLDGDAPHEVMLTLDASTGQNAVSQAKLFNEAVGLTGITLTKLDGTAKGG
VIFAIADQFEIPIRYIGVGEGIEDLRPFKADEFIEALFARED

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=203, Percent_Identity=34.4827586206897, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4507215, Length=203, Percent_Identity=34.4827586206897, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI295424842, Length=330, Percent_Identity=29.0909090909091, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI23308697, Length=330, Percent_Identity=29.0909090909091, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI89061728, Length=147, Percent_Identity=30.6122448979592, Blast_Score=83, Evalue=8e-16,
Organism=Escherichia coli, GI1789874, Length=322, Percent_Identity=86.3354037267081, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1788963, Length=277, Percent_Identity=33.2129963898917, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI193206261, Length=312, Percent_Identity=32.0512820512821, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17539958, Length=229, Percent_Identity=30.5676855895196, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=203, Percent_Identity=36.9458128078818, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320498, Length=250, Percent_Identity=32.8, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17647949, Length=284, Percent_Identity=30.9859154929577, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24641198, Length=325, Percent_Identity=29.5384615384615, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 56674; Mature: 56543

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEKKRGFFSWLGLGRQSEEPAAEPLATEKEGVTEQEDVIEQTGVIEQTVEHVISEKTT
CCCCHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHCCC
EAPAENAFIEVELREQVAAVIPTEPNNAIMSEGVPDTLPERAVAESVVAELVETGDNAAI
CCCCCCCEEEEEEHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
VHDEIIEPITQVTEAGGELSLVKPGIEGDTTEQGGPTDNLPKRSLTEDNLIIDVPTPQAV
EHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHH
VEESRVDAVEQPTETSEVEEVEEKIIPVAAQEQERPTKEGFFARLKRSLIKTKQNLGSGF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCH
MGLFSGKKIDDDLFEELEEQLLIADVGVETTRKIITSLTEHTSRKQLKDADALYGKLKEE
HHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSEILSKVDKPLDVSGKSPYVILMVGVNGVGKTTTIGKLARQFQAEGKSVMLAAGDTFRA
HHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHH
AAVEQLQVWGERNKIAVVAQHTGADSASVIFDAIQAAKARGIDVLLADTAGRLQNKAHLM
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHH
EELKKIVRVMKKLDGDAPHEVMLTLDASTGQNAVSQAKLFNEAVGLTGITLTKLDGTAKG
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GVIFAIADQFEIPIRYIGVGEGIEDLRPFKADEFIEALFARED
CEEEEEECCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AKEKKRGFFSWLGLGRQSEEPAAEPLATEKEGVTEQEDVIEQTGVIEQTVEHVISEKTT
CCCHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHCCC
EAPAENAFIEVELREQVAAVIPTEPNNAIMSEGVPDTLPERAVAESVVAELVETGDNAAI
CCCCCCCEEEEEEHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
VHDEIIEPITQVTEAGGELSLVKPGIEGDTTEQGGPTDNLPKRSLTEDNLIIDVPTPQAV
EHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHH
VEESRVDAVEQPTETSEVEEVEEKIIPVAAQEQERPTKEGFFARLKRSLIKTKQNLGSGF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCH
MGLFSGKKIDDDLFEELEEQLLIADVGVETTRKIITSLTEHTSRKQLKDADALYGKLKEE
HHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSEILSKVDKPLDVSGKSPYVILMVGVNGVGKTTTIGKLARQFQAEGKSVMLAAGDTFRA
HHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHH
AAVEQLQVWGERNKIAVVAQHTGADSASVIFDAIQAAKARGIDVLLADTAGRLQNKAHLM
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHH
EELKKIVRVMKKLDGDAPHEVMLTLDASTGQNAVSQAKLFNEAVGLTGITLTKLDGTAKG
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GVIFAIADQFEIPIRYIGVGEGIEDLRPFKADEFIEALFARED
CEEEEEECCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]