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The map label for this gene is actP [H]

Identifier: 170026136

GI number: 170026136

Start: 4323579

End: 4325234

Strand: Direct

Name: actP [H]

Synonym: YPK_3923

Alternate gene names: 170026136

Gene position: 4323579-4325234 (Clockwise)

Preceding gene: 170026135

Following gene: 170026144

Centisome position: 92.2

GC content: 46.86

Gene sequence:

>1656_bases
ATGAAGATCCGCCATTGGTCTGCACTTTCTTTATTCGTTTTGCCTGCGCTAGCACAGGCGGAAGCACTTACCGGCGAGGT
CCACCGCCAACCCCTCAATATTCAGGCGATCGTCATGTTTTTGCTGTTTGTTGGCGGAACCTTGTATATCACCTATTGGG
CATCAAAACGTACTCGCTCCCGGCAAGATTATTACACGGCTGGCGGGCGAATTACTGGCTTTCAAAATGGTTTAGCCATC
GCTGGGGATTATATGTCCGCAGCATCATTCCTCGGTATTTCAGCCTTGGTTTATGCTTCCGGTTACGACGGTTTAATTTA
CTCCATCGGCTTCTTAATCGGCTGGCCCATTATTCTATTTTTAATTGCTGAACGCCTGCGTAATTTGGGGCGTTATACCT
TTGCCGATGTTGCCTCTTACCGCTTGCAACAAAGACCCATACGCACATTATCAGCCTGTGGTTCGTTAGTCGTTGTCGCC
CTGTATTTGATCGCTCAGATGGTGGGGGCAGGTAAACTCATTCAACTTTTATTTGGTTTGAACTACCACGTCGCTGTCGT
GTTGGTTGGTATCCTGATGGTGCTGTACGTCCTGTTCGGCGGTATGTTAGCAACCACTTGGGTACAGATAATCAAAGCGG
TCATGCTACTGTCTGGTGCCACATTTATGGCTATTATGGTCATGAAATCAGTTAATTTTAACTTCAATACGTTATTCAGT
GAGGCGGTTAAAGTTCATCCCAAAGGCCTTAGCATCATGAGCCCAGGAGGGTTGGTATCTGACCCGATATCAGCATTATC
TCTTGGTTTGGCCCTCATGTTTGGCACTGCTGGCTTACCTCATATCCTGATGCGCTTCTTTACCGTAAGCGATGCCAAAG
AAGCACGTAAAAGCGTGTTCTATGCCACAGGTTTTATAGGCTACTTCTACATATTGACCTTTATTATTGGATTCGGCGCG
ATCTTACTCGTCGGTCCAAACCAGACATTTAAAGATGCGGCTGGCGCATTACTGGGTGGTAACAATATGGCTGCGGTCCA
TTTGGCTAATGCTGTCGGGGGGAGCTTCTTCTTAGGCTTTATCTCAGCGGTTGCCTTCGCAACCATTTTGGCTGTAGTGG
CTGGCTTGACATTAGCCGGTGCATCGGCGGTATCTCATGATCTCTATGCCAGCGTCATTAAGAAAGGCAAAGCCAATGAA
CGCGATGAATTGAGAGTCTCCAAAATTACGGTAATCATCTTAGGTATCGTCGCTATTGGTTTGGGGATTTTGTTTGAAAA
ACAGAATATTGCCTTTATGGTCGGGTTGGCATTCTCCATTGCGGCCAGTTGTAACTTCCCAATTATTATCATCTCAATGT
ATTGGGATAAACTGACAACCCGTGGAGCAATGATCGGTGGGTGGCTCGGGTTATCAACGGCAGTGATCCTGATGATTTTA
GGCCCTACGATCTGGGTAACAATCCTTGGTCATGAAAAGCCAATCTATCCGTATGAGTACCCTGCATTGTTTTCAATGAT
AGCGGCGTTCGTCGGTACCTGGTTCTTCTCAATCACTGATAACTCAGAAACCGGCAAACAGGAACGGTTACTATTCAAAT
CACAGTTTGTCCGTTCACAAACCGGCTTGGGGGCATCTAAAGGCGGCGCTCACTGA

Upstream 100 bases:

>100_bases
GATTAATTGTTACTTCTTTTATTCTTACAGGTATTTATGTTATCCGCGCTAATGGCGAATTTGACCGTCTGACGGCAGAA
ATTATTCGTGAGGTGAAGCA

Downstream 100 bases:

>100_bases
TAATATTTACAGGTTAAAAGGCCCTTAGGGGCCTAGATTGCTGACAAAGCCCTGGTCTTCTGGCTGGGGCTAGTCATTTT
AGCCAACGGTCTAGCCACAA

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MKIRHWSALSLFVLPALAQAEALTGEVHRQPLNIQAIVMFLLFVGGTLYITYWASKRTRSRQDYYTAGGRITGFQNGLAI
AGDYMSAASFLGISALVYASGYDGLIYSIGFLIGWPIILFLIAERLRNLGRYTFADVASYRLQQRPIRTLSACGSLVVVA
LYLIAQMVGAGKLIQLLFGLNYHVAVVLVGILMVLYVLFGGMLATTWVQIIKAVMLLSGATFMAIMVMKSVNFNFNTLFS
EAVKVHPKGLSIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGA
ILLVGPNQTFKDAAGALLGGNNMAAVHLANAVGGSFFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKANE
RDELRVSKITVIILGIVAIGLGILFEKQNIAFMVGLAFSIAASCNFPIIIISMYWDKLTTRGAMIGGWLGLSTAVILMIL
GPTIWVTILGHEKPIYPYEYPALFSMIAAFVGTWFFSITDNSETGKQERLLFKSQFVRSQTGLGASKGGAH

Sequences:

>Translated_551_residues
MKIRHWSALSLFVLPALAQAEALTGEVHRQPLNIQAIVMFLLFVGGTLYITYWASKRTRSRQDYYTAGGRITGFQNGLAI
AGDYMSAASFLGISALVYASGYDGLIYSIGFLIGWPIILFLIAERLRNLGRYTFADVASYRLQQRPIRTLSACGSLVVVA
LYLIAQMVGAGKLIQLLFGLNYHVAVVLVGILMVLYVLFGGMLATTWVQIIKAVMLLSGATFMAIMVMKSVNFNFNTLFS
EAVKVHPKGLSIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGA
ILLVGPNQTFKDAAGALLGGNNMAAVHLANAVGGSFFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKANE
RDELRVSKITVIILGIVAIGLGILFEKQNIAFMVGLAFSIAASCNFPIIIISMYWDKLTTRGAMIGGWLGLSTAVILMIL
GPTIWVTILGHEKPIYPYEYPALFSMIAAFVGTWFFSITDNSETGKQERLLFKSQFVRSQTGLGASKGGAH
>Mature_551_residues
MKIRHWSALSLFVLPALAQAEALTGEVHRQPLNIQAIVMFLLFVGGTLYITYWASKRTRSRQDYYTAGGRITGFQNGLAI
AGDYMSAASFLGISALVYASGYDGLIYSIGFLIGWPIILFLIAERLRNLGRYTFADVASYRLQQRPIRTLSACGSLVVVA
LYLIAQMVGAGKLIQLLFGLNYHVAVVLVGILMVLYVLFGGMLATTWVQIIKAVMLLSGATFMAIMVMKSVNFNFNTLFS
EAVKVHPKGLSIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGA
ILLVGPNQTFKDAAGALLGGNNMAAVHLANAVGGSFFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKANE
RDELRVSKITVIILGIVAIGLGILFEKQNIAFMVGLAFSIAASCNFPIIIISMYWDKLTTRGAMIGGWLGLSTAVILMIL
GPTIWVTILGHEKPIYPYEYPALFSMIAAFVGTWFFSITDNSETGKQERLLFKSQFVRSQTGLGASKGGAH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=509, Percent_Identity=23.9685658153242, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI1790503, Length=539, Percent_Identity=82.0037105751391, Blast_Score=887, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=460, Percent_Identity=24.7826086956522, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87082237, Length=429, Percent_Identity=21.9114219114219, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 59325; Mature: 59325

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRHWSALSLFVLPALAQAEALTGEVHRQPLNIQAIVMFLLFVGGTLYITYWASKRTRS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCC
RQDYYTAGGRITGFQNGLAIAGDYMSAASFLGISALVYASGYDGLIYSIGFLIGWPIILF
CCCCCCCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LIAERLRNLGRYTFADVASYRLQQRPIRTLSACGSLVVVALYLIAQMVGAGKLIQLLFGL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
NYHVAVVLVGILMVLYVLFGGMLATTWVQIIKAVMLLSGATFMAIMVMKSVNFNFNTLFS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHH
EAVKVHPKGLSIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVF
HHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHH
YATGFIGYFYILTFIIGFGAILLVGPNQTFKDAAGALLGGNNMAAVHLANAVGGSFFLGF
HHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHCCCEECCCCEEEEEEHHHHHHHHHHHH
ISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKANERDELRVSKITVIILGIVAIG
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LGILFEKQNIAFMVGLAFSIAASCNFPIIIISMYWDKLTTRGAMIGGWLGLSTAVILMIL
HHHHEECCCCEEEHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHH
GPTIWVTILGHEKPIYPYEYPALFSMIAAFVGTWFFSITDNSETGKQERLLFKSQFVRSQ
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHH
TGLGASKGGAH
CCCCCCCCCCC
>Mature Secondary Structure
MKIRHWSALSLFVLPALAQAEALTGEVHRQPLNIQAIVMFLLFVGGTLYITYWASKRTRS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCC
RQDYYTAGGRITGFQNGLAIAGDYMSAASFLGISALVYASGYDGLIYSIGFLIGWPIILF
CCCCCCCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LIAERLRNLGRYTFADVASYRLQQRPIRTLSACGSLVVVALYLIAQMVGAGKLIQLLFGL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
NYHVAVVLVGILMVLYVLFGGMLATTWVQIIKAVMLLSGATFMAIMVMKSVNFNFNTLFS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHH
EAVKVHPKGLSIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVF
HHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHH
YATGFIGYFYILTFIIGFGAILLVGPNQTFKDAAGALLGGNNMAAVHLANAVGGSFFLGF
HHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHCCCEECCCCEEEEEEHHHHHHHHHHHH
ISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKANERDELRVSKITVIILGIVAIG
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LGILFEKQNIAFMVGLAFSIAASCNFPIIIISMYWDKLTTRGAMIGGWLGLSTAVILMIL
HHHHEECCCCEEEHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHH
GPTIWVTILGHEKPIYPYEYPALFSMIAAFVGTWFFSITDNSETGKQERLLFKSQFVRSQ
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHH
TGLGASKGGAH
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA