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The map label for this gene is pilC [H]

Identifier: 170025715

GI number: 170025715

Start: 3846906

End: 3848042

Strand: Direct

Name: pilC [H]

Synonym: YPK_3500

Alternate gene names: 170025715

Gene position: 3846906-3848042 (Clockwise)

Preceding gene: 170025714

Following gene: 170025717

Centisome position: 82.03

GC content: 45.47

Gene sequence:

>1137_bases
ATGCTACTGGCAACTGAGAGAAACAGTGTCTATGAACATATCATCCAACATGGCTTACAGCCCCTAGGCGTGAAAGGGGG
AAGGCGGTTATCTGCACGCTACTGGCAAGGGGAACGGTTGGTGGCAATGACCCGCCAATTAGCGACTTTATTGCAAGCGG
GTTTACCGTTGGTCAACAGTTTACAGTTATTGGCAAAAGAGGCAGATGACTCAGCATGGCGTTGCCTATTAGATGAGATA
AGTCAGCAAGTTGCACAAGGCCAGTCACTCTCGGAAGTGATGGAACAGTATCCACACGTATTCCCCCGACTGTATCCTCC
AGTGGTTGCCGTCGGGGAGCTTACGGGTAATCTTGAGCAATGTTGTACTCAATTAGTACACCATCAGGAACGGCAGCAAA
ATTTACACAAAAAAGTCATAAAAGCGCTGAAATACCCCGTTGTGGTCTGCATCGTCGCATTGGTAGTCAGTGTCATTATG
TTAGTCATGGTGTTACCCGAATTTGCACAAATATATCAATCGTTTGATACCCCCCTGCCGGGGCTAACTGCAAGCTTACT
GTGGCTATCAACTTTTCTCACTTTTTATGGCCCCTATCTGGCGCTGATAATAGCAATAGTGTGTATTGGGTATTTCTATA
CATTACGAAAAAAATCTCGCTGGCAGCAATGGGAACAGACCATTCTATTAAGCATTCCCTTGGTCTCAACATTAATCCGT
GGTAGCTGCCTCAGCCAAATTTTTCAAACGTTAGCTATCACACAACAAGCCGGGCTACCCCTGTCAGCCGGGTTAGATGC
AGCGGCTCGATCCATTCACAATTACAATTATCAGCAAGCCTTAAGGTGTATTCAAAAACAAATTAGCCAAGGTATACCGC
TGTATACCACTCTTAATCAGCACCCTTTATTTCCTGCCATTTGTCAGCAGCTCATTAGGGTTGGTGAAGAATCAGGCTCA
CTGGATGTGTTGCTGGAAAAGTTAGCCTGTTGGCATCAGCAACAAACTCAGAATTTGGCAGATAACGTCACTCAAATGCT
AGAGCCACTTCTTATGCTGATTATTGGCAGTATTGTCGGCGTACTGGTGATCGCCATGTATTTACCCATATTCCAGTTAG
GTGATGTTATCGGGTAA

Upstream 100 bases:

>100_bases
GTGTTGTGGGCTTCGTAGCAGAAACAGAGGTCACCTCTTGAGCCGCCATCGTTTATTCAATTGGACAGCTCTCAACAAAA
CAGGGGAGCTACAGACGGGC

Downstream 100 bases:

>100_bases
CCTCATTATGGACCTAGTGGATGGTGAACTAGGCATCGTGGAGTGCATGGCATGGCATGGCGGGATGTAATGGCACGATC
AGGTGCAAGATCAGAGAGGC

Product: type IV pilin biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MLLATERNSVYEHIIQHGLQPLGVKGGRRLSARYWQGERLVAMTRQLATLLQAGLPLVNSLQLLAKEADDSAWRCLLDEI
SQQVAQGQSLSEVMEQYPHVFPRLYPPVVAVGELTGNLEQCCTQLVHHQERQQNLHKKVIKALKYPVVVCIVALVVSVIM
LVMVLPEFAQIYQSFDTPLPGLTASLLWLSTFLTFYGPYLALIIAIVCIGYFYTLRKKSRWQQWEQTILLSIPLVSTLIR
GSCLSQIFQTLAITQQAGLPLSAGLDAAARSIHNYNYQQALRCIQKQISQGIPLYTTLNQHPLFPAICQQLIRVGEESGS
LDVLLEKLACWHQQQTQNLADNVTQMLEPLLMLIIGSIVGVLVIAMYLPIFQLGDVIG

Sequences:

>Translated_378_residues
MLLATERNSVYEHIIQHGLQPLGVKGGRRLSARYWQGERLVAMTRQLATLLQAGLPLVNSLQLLAKEADDSAWRCLLDEI
SQQVAQGQSLSEVMEQYPHVFPRLYPPVVAVGELTGNLEQCCTQLVHHQERQQNLHKKVIKALKYPVVVCIVALVVSVIM
LVMVLPEFAQIYQSFDTPLPGLTASLLWLSTFLTFYGPYLALIIAIVCIGYFYTLRKKSRWQQWEQTILLSIPLVSTLIR
GSCLSQIFQTLAITQQAGLPLSAGLDAAARSIHNYNYQQALRCIQKQISQGIPLYTTLNQHPLFPAICQQLIRVGEESGS
LDVLLEKLACWHQQQTQNLADNVTQMLEPLLMLIIGSIVGVLVIAMYLPIFQLGDVIG
>Mature_378_residues
MLLATERNSVYEHIIQHGLQPLGVKGGRRLSARYWQGERLVAMTRQLATLLQAGLPLVNSLQLLAKEADDSAWRCLLDEI
SQQVAQGQSLSEVMEQYPHVFPRLYPPVVAVGELTGNLEQCCTQLVHHQERQQNLHKKVIKALKYPVVVCIVALVVSVIM
LVMVLPEFAQIYQSFDTPLPGLTASLLWLSTFLTFYGPYLALIIAIVCIGYFYTLRKKSRWQQWEQTILLSIPLVSTLIR
GSCLSQIFQTLAITQQAGLPLSAGLDAAARSIHNYNYQQALRCIQKQISQGIPLYTTLNQHPLFPAICQQLIRVGEESGS
LDVLLEKLACWHQQQTQNLADNVTQMLEPLLMLIIGSIVGVLVIAMYLPIFQLGDVIG

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1786295, Length=377, Percent_Identity=40.053050397878, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1789724, Length=356, Percent_Identity=29.4943820224719, Blast_Score=161, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 42295; Mature: 42295

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]