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The map label for this gene is speD [H]

Identifier: 170025698

GI number: 170025698

Start: 3825543

End: 3826337

Strand: Direct

Name: speD [H]

Synonym: YPK_3483

Alternate gene names: 170025698

Gene position: 3825543-3826337 (Clockwise)

Preceding gene: 170025697

Following gene: 170025700

Centisome position: 81.58

GC content: 46.16

Gene sequence:

>795_bases
TTGTCCAAGCTTAAACTGCACGGCTTCAACAACCTGACCAAAAGCCTGAGTTTTTGTATTTACGATATTTGTTATGCCAA
GACCGCAGACGACCGCGATGGCTATATCGCCTACATTGACGAACAGTACAATGCCAATCGCTTGACCGAGATCTTGAGCG
AAACCTGCTCGATCATCGGTGCCAATATTTTAAATATTGCTCGTCAGGATTACGATCCACAAGGTGCCAGCGTCACCATT
TTGGTCAGTGAAGAGCCCGTTGATCCACGCGATGTTGATACCTCCGAACATCCCGGCCCATTGCCAAGCGCCGTGGTGGC
CCACCTGGATAAGAGCCATATCTGTGTGCATACTTATCCAGAAAGCCACCCTGAAGCGGGGTTATGTACTTTCCGTGCCG
ATATCGAGGTCTCTACCTGTGGGGTGATTTCTCCGCTGAAGGCCCTGAATTACCTGATCCATCAGCTCGAATCCGATATC
GTGACCATGGATTACCGGGTACGGGGTTTCACCCGAGATATCAATGGGGTAAAACATTTTATCGATCACAAAATCAATTC
CATTCAGAATTTTATGTCCGATGACATGAAGTCGCTTTATCACATGATGGATGTGAATGTTTATCAGGAAAATATCTTCC
ATACCAAGATGATGCTGAAAGATTTCGATTTAAAGCATTATCTGTTTAACGCCAAGCCGGAAGAGCTAAGCGCAGAAGAA
AAGGAACAGATTACCCGCCTGTTATACAAAGAAATGCAGGAAATCTACTATGGCCGCAATGTGCCGGAAGTGTGA

Upstream 100 bases:

>100_bases
TTGGCCTCGATTCAAGTGAATAAGAGCCGCTAGCAACGCAGTAGTGCCGAGTAAAAAAGGGATAAATGTTGAGTATTCAT
TTGTAAGGAGGTGAACTAAA

Downstream 100 bases:

>100_bases
TGCATTACAGCCTAGGCTCTAAATAATTCTGTATAACTGATACGGAATTAAAGGTGATCGTTCAGGCGATCACCTAAAAA
CGGCTCGTCGTAATTACCCG

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYIAYIDEQYNANRLTEILSETCSIIGANILNIARQDYDPQGASVTI
LVSEEPVDPRDVDTSEHPGPLPSAVVAHLDKSHICVHTYPESHPEAGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
VTMDYRVRGFTRDINGVKHFIDHKINSIQNFMSDDMKSLYHMMDVNVYQENIFHTKMMLKDFDLKHYLFNAKPEELSAEE
KEQITRLLYKEMQEIYYGRNVPEV

Sequences:

>Translated_264_residues
MSKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYIAYIDEQYNANRLTEILSETCSIIGANILNIARQDYDPQGASVTI
LVSEEPVDPRDVDTSEHPGPLPSAVVAHLDKSHICVHTYPESHPEAGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
VTMDYRVRGFTRDINGVKHFIDHKINSIQNFMSDDMKSLYHMMDVNVYQENIFHTKMMLKDFDLKHYLFNAKPEELSAEE
KEQITRLLYKEMQEIYYGRNVPEV
>Mature_263_residues
SKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYIAYIDEQYNANRLTEILSETCSIIGANILNIARQDYDPQGASVTIL
VSEEPVDPRDVDTSEHPGPLPSAVVAHLDKSHICVHTYPESHPEAGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIV
TMDYRVRGFTRDINGVKHFIDHKINSIQNFMSDDMKSLYHMMDVNVYQENIFHTKMMLKDFDLKHYLFNAKPEELSAEEK
EQITRLLYKEMQEIYYGRNVPEV

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786311, Length=264, Percent_Identity=85.9848484848485, Blast_Score=487, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR009165
- InterPro:   IPR016067 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 30294; Mature: 30162

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYIAYIDEQYNANRLTEILSETCSIIG
CCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
ANILNIARQDYDPQGASVTILVSEEPVDPRDVDTSEHPGPLPSAVVAHLDKSHICVHTYP
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEECCC
ESHPEAGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTMDYRVRGFTRDINGVKHF
CCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHH
IDHKINSIQNFMSDDMKSLYHMMDVNVYQENIFHTKMMLKDFDLKHYLFNAKPEELSAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHCCHHH
KEQITRLLYKEMQEIYYGRNVPEV
HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYIAYIDEQYNANRLTEILSETCSIIG
CCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
ANILNIARQDYDPQGASVTILVSEEPVDPRDVDTSEHPGPLPSAVVAHLDKSHICVHTYP
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEECCC
ESHPEAGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTMDYRVRGFTRDINGVKHF
CCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHH
IDHKINSIQNFMSDDMKSLYHMMDVNVYQENIFHTKMMLKDFDLKHYLFNAKPEELSAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHCCHHH
KEQITRLLYKEMQEIYYGRNVPEV
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA