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The map label for this gene is dmsC [H]

Identifier: 170025607

GI number: 170025607

Start: 3721749

End: 3722609

Strand: Reverse

Name: dmsC [H]

Synonym: YPK_3392

Alternate gene names: 170025607

Gene position: 3722609-3721749 (Counterclockwise)

Preceding gene: 170025608

Following gene: 170025606

Centisome position: 79.38

GC content: 53.89

Gene sequence:

>861_bases
ATGGGCTCAGGATGGCATGAATGGCCACTAATGGTCTTTACCGTACTGGGGCAGTGTGTGGTCGGGGGCTTTATTGTTCT
CGGTCTGGCACTGATATTCGGTGGTTTGAGTCGCGGGCAACAACAGCGGGTTCACCGCAGCATGTTTGTGCTTTGGGTGC
TGATGGCACTGGCTTTTATCGCCTCTACACTGCATTTAGGTTCGCCAATGCGGGCGTTCAACTCATTGAATCGGATCGGT
GAATCTGCACTGAGTAATGAGATTGCCGCCGGTTCGTTGTTCTTTGCTGTGGCCGGTTTTTACTGGTTGTTGGCGGTGTT
GGATAAAATGCCTGCCGCGCTTGGTAAGATCTGGCTGGTGGTGGCAATGGTGTTGGGCGTGATCTTTGTCTACGCCATGT
GCCGGGTCTACTCCATTAATACGGTACCGACGTGGGACAGTATTTATACCCCGCTGGGCTTTGTCCTGACCACGTTGATC
GGTGGCCCGCTATTGGGTTATCTGTTGCTGCAATTGGCTGATGTTAATGGGCGGGCGATGTTACAACTGCCGATGATCAG
CGTATTGGCACTGATCATCAGTGTGGCCAGTGTCATTATGCAGGCGGCCAGTTTGCCGCTGATTTATAGCTCGGTACAGC
AAGCTTCAGCGCTGATCCCCGACTATGGCTCATTGATGGTATGGCGGTTAGTGCTGCTGGTGTTGGGGCTTGGCTGCTGG
ATTTGCCCGTTGATCAGAGGCCGTCGCCCGATGACGCTGGTGATGGTCTTGGGCACGTTACTGGTTATTGCCGGTGAGTT
GATTGGCCGTGGGGTGTTCTACGGGTTACATATGACGGTCGGTATGGCGGTTGGGGGCTAA

Upstream 100 bases:

>100_bases
GCTCACTTCACGCTGCCGAATATCGTACTAAAACCTAATGCCAACAGCCGCCCGGTCAGAGATACCACCGGTCATCTGGC
AAACCCGAAGGAGGTATAAC

Downstream 100 bases:

>100_bases
TCTCCAGACGGCGGCGACACTTTGGCTATTCTGGGGAGCGCCCAGAATAGCTTTGCTCTGCCTCATGGCGTGCTAAAACC
AAGGTCATACAGGGCCGAAC

Product: DMSO reductase anchor subunit DmsC

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase anchor subunit [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MGSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRGQQQRVHRSMFVLWVLMALAFIASTLHLGSPMRAFNSLNRIG
ESALSNEIAAGSLFFAVAGFYWLLAVLDKMPAALGKIWLVVAMVLGVIFVYAMCRVYSINTVPTWDSIYTPLGFVLTTLI
GGPLLGYLLLQLADVNGRAMLQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALIPDYGSLMVWRLVLLVLGLGCW
ICPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMTVGMAVGG

Sequences:

>Translated_286_residues
MGSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRGQQQRVHRSMFVLWVLMALAFIASTLHLGSPMRAFNSLNRIG
ESALSNEIAAGSLFFAVAGFYWLLAVLDKMPAALGKIWLVVAMVLGVIFVYAMCRVYSINTVPTWDSIYTPLGFVLTTLI
GGPLLGYLLLQLADVNGRAMLQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALIPDYGSLMVWRLVLLVLGLGCW
ICPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMTVGMAVGG
>Mature_285_residues
GSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRGQQQRVHRSMFVLWVLMALAFIASTLHLGSPMRAFNSLNRIGE
SALSNEIAAGSLFFAVAGFYWLLAVLDKMPAALGKIWLVVAMVLGVIFVYAMCRVYSINTVPTWDSIYTPLGFVLTTLIG
GPLLGYLLLQLADVNGRAMLQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALIPDYGSLMVWRLVLLVLGLGCWI
CPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMTVGMAVGG

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the dmsAB dimer to the membrane and stabilizes it [H]

COG id: COG3302

COG function: function code R; DMSO reductase anchor subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli ynfH [H]

Homologues:

Organism=Escherichia coli, GI1787123, Length=285, Percent_Identity=66.6666666666667, Blast_Score=334, Evalue=4e-93,
Organism=Escherichia coli, GI1787873, Length=286, Percent_Identity=59.7902097902098, Blast_Score=315, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007059 [H]

Pfam domain/function: PF04976 DmsC [H]

EC number: NA

Molecular weight: Translated: 30788; Mature: 30657

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRGQQQRVHRSMFVLWVLMALAFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ASTLHLGSPMRAFNSLNRIGESALSNEIAAGSLFFAVAGFYWLLAVLDKMPAALGKIWLV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMVLGVIFVYAMCRVYSINTVPTWDSIYTPLGFVLTTLIGGPLLGYLLLQLADVNGRAM
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALIPDYGSLMVWRLVLLVLGLGCW
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ICPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMTVGMAVGG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 8429002; 2170332 [H]