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The map label for this gene is luxS [H]

Identifier: 170025583

GI number: 170025583

Start: 3693992

End: 3694507

Strand: Reverse

Name: luxS [H]

Synonym: YPK_3368

Alternate gene names: 170025583

Gene position: 3694507-3693992 (Counterclockwise)

Preceding gene: 170025584

Following gene: 170025580

Centisome position: 78.78

GC content: 47.67

Gene sequence:

>516_bases
ATGCCATTATTGGATAGCTTTACCGTAGACCATACCATTATGAAAGCACCGGCAGTACGTGTCGCTAAGACGATGAAAAC
TCCTCATGGCGACGAGATAACGGTGTTTGATTTACGCTTCTGTGTGCCGAATAAAGAAGTGATGCCAGAGAAAGGGATCC
ATACGCTAGAGCACTTATTCGCTGGGTTTATGCGGGACCACCTCAATGGTGATGGTGTTGAAATTATTGATATCTCGCCG
ATGGGATGTCGCACGGGTTTCTACATGAGTCTGATAGGGACACCTGACGAGCAACGGGTTGCTGATGCCTGGAAAGCGGC
AATGGCGGACGTGCTGAAGGTCACTGACCAGCGGAAGATCCCTGAGCTGAATGAATATCAGTGCGGGACTTATCATATGC
ACTCGCTGGAAGAAGCTCAGAGTATTGCTAAAGATATTCTTGACCGTGATGTGCGTATCAACCACAACGAAGAGTTGGCA
CTGCCGAAAGAGAAACTGACTGAATTGCATATTTAG

Upstream 100 bases:

>100_bases
CGCGTCTTTCACATATTAAGACGCGCAGGATGAGTAAAAGTTTCATCAGTTGCGAAAAAAAGATTAGAAAAATATGACTT
TTTTATGAGGAGGTAACTAA

Downstream 100 bases:

>100_bases
TGCTCAGTATCAGTAGGCAGGAGAATGATAAAAGGCGCTGATTAAAGCGTCTTTTTTATTAAACTGACTATCGCTTAGAC
AGAATTATTTATAGGGTCGA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MPLLDSFTVDHTIMKAPAVRVAKTMKTPHGDEITVFDLRFCVPNKEVMPEKGIHTLEHLFAGFMRDHLNGDGVEIIDISP
MGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVTDQRKIPELNEYQCGTYHMHSLEEAQSIAKDILDRDVRINHNEELA
LPKEKLTELHI

Sequences:

>Translated_171_residues
MPLLDSFTVDHTIMKAPAVRVAKTMKTPHGDEITVFDLRFCVPNKEVMPEKGIHTLEHLFAGFMRDHLNGDGVEIIDISP
MGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVTDQRKIPELNEYQCGTYHMHSLEEAQSIAKDILDRDVRINHNEELA
LPKEKLTELHI
>Mature_170_residues
PLLDSFTVDHTIMKAPAVRVAKTMKTPHGDEITVFDLRFCVPNKEVMPEKGIHTLEHLFAGFMRDHLNGDGVEIIDISPM
GCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVTDQRKIPELNEYQCGTYHMHSLEEAQSIAKDILDRDVRINHNEELAL
PKEKLTELHI

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=171, Percent_Identity=88.3040935672515, Blast_Score=321, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 19397; Mature: 19265

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTIMKAPAVRVAKTMKTPHGDEITVFDLRFCVPNKEVMPEKGIHTLEHLF
CCCCCCCCCCHHHHHCHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHH
AGFMRDHLNGDGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVTDQRKI
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
PELNEYQCGTYHMHSLEEAQSIAKDILDRDVRINHNEELALPKEKLTELHI
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
PLLDSFTVDHTIMKAPAVRVAKTMKTPHGDEITVFDLRFCVPNKEVMPEKGIHTLEHLF
CCCCCCCCCHHHHHCHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHH
AGFMRDHLNGDGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVTDQRKI
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
PELNEYQCGTYHMHSLEEAQSIAKDILDRDVRINHNEELALPKEKLTELHI
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA