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The map label for this gene is yecS [H]

Identifier: 170025544

GI number: 170025544

Start: 3648184

End: 3648837

Strand: Reverse

Name: yecS [H]

Synonym: YPK_3327

Alternate gene names: 170025544

Gene position: 3648837-3648184 (Counterclockwise)

Preceding gene: 170025545

Following gene: 170025543

Centisome position: 77.81

GC content: 52.29

Gene sequence:

>654_bases
ATGACATTTACTGACTGGGATATCATCCGCAACCTGCTATTGGCGGCCCGCTGGACGCTGTTACTGTCACTCACGGCCTT
CTTCGGTGGCACGTTGGTGACATTACCGCTAATGCTGATGCGGTTGAGCCACTGGCGTTGGGCGGCGCGCTTTGTCCGTT
TATATACCGAGCTGTTCCAAGGAACCCCGTTATTGATGCAGCTATTTTTGGCCTTTTTCGGTCTGGCGCTGTTTGGCATC
GATGTTAGCCCGTGGACAGCAGCGGCCATGGCACTCACCTTATTCACCAGTGCATTTTTGGTGGATATCTGGTGCGGCAG
TATCGCCGCTTTGCCGAAAGGCCAGTGGGAAGCATCACGTTGCTTGGGGTTGAGTTTTCACCAAACGCTCTTTCGGGTGA
TTGCCCCACAAGCGATGCGTATCGCGATTGCGCCAACCGTAGGGTTTTCGGTGCAGGTTATCAAAGGCACGGCGCTGGCC
TCCATCATTGGTTTTGTCGAGCTAACCAAAGCGGGCACTATGCTGAACAATGTCACTTATCAGCCATTTAAAGTCTTTGG
GCTGGTCGCGCTGGGCTATTTCCTGATGTGTTATCCCCTGTCGCGTTATAGCCATTATCTGGAGAAGAAATTCCATGCCA
TTGATCACCATTAA

Upstream 100 bases:

>100_bases
AGGTCTATCTGGTGACCACCTTGCTGTATTTGTTGTTCGCTATCGTGATGCGCCAGCTATTGCTGGCGGCCGGGCGTCGA
TACTTTGGGAGCCATGCCTC

Downstream 100 bases:

>100_bases
TCAGGTTCAAAAATACTATGGTAAGAACCATGTGCTTAAAGGCGTGGATTTGGATATCGAGATTGGTGAAGTGATTTCGA
TCATTGGTCGCAGTGGCTCG

Product: polar amino acid ABC transporter inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MTFTDWDIIRNLLLAARWTLLLSLTAFFGGTLVTLPLMLMRLSHWRWAARFVRLYTELFQGTPLLMQLFLAFFGLALFGI
DVSPWTAAAMALTLFTSAFLVDIWCGSIAALPKGQWEASRCLGLSFHQTLFRVIAPQAMRIAIAPTVGFSVQVIKGTALA
SIIGFVELTKAGTMLNNVTYQPFKVFGLVALGYFLMCYPLSRYSHYLEKKFHAIDHH

Sequences:

>Translated_217_residues
MTFTDWDIIRNLLLAARWTLLLSLTAFFGGTLVTLPLMLMRLSHWRWAARFVRLYTELFQGTPLLMQLFLAFFGLALFGI
DVSPWTAAAMALTLFTSAFLVDIWCGSIAALPKGQWEASRCLGLSFHQTLFRVIAPQAMRIAIAPTVGFSVQVIKGTALA
SIIGFVELTKAGTMLNNVTYQPFKVFGLVALGYFLMCYPLSRYSHYLEKKFHAIDHH
>Mature_216_residues
TFTDWDIIRNLLLAARWTLLLSLTAFFGGTLVTLPLMLMRLSHWRWAARFVRLYTELFQGTPLLMQLFLAFFGLALFGID
VSPWTAAAMALTLFTSAFLVDIWCGSIAALPKGQWEASRCLGLSFHQTLFRVIAPQAMRIAIAPTVGFSVQVIKGTALAS
IIGFVELTKAGTMLNNVTYQPFKVFGLVALGYFLMCYPLSRYSHYLEKKFHAIDHH

Specific function: Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=35.5140186915888, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI87082239, Length=203, Percent_Identity=31.5270935960591, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788645, Length=200, Percent_Identity=32, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1787030, Length=210, Percent_Identity=29.5238095238095, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787086, Length=177, Percent_Identity=31.638418079096, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788646, Length=184, Percent_Identity=29.8913043478261, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI48994930, Length=132, Percent_Identity=32.5757575757576, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786874, Length=191, Percent_Identity=26.1780104712042, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1787087, Length=124, Percent_Identity=34.6774193548387, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24407; Mature: 24276

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFTDWDIIRNLLLAARWTLLLSLTAFFGGTLVTLPLMLMRLSHWRWAARFVRLYTELFQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTPLLMQLFLAFFGLALFGIDVSPWTAAAMALTLFTSAFLVDIWCGSIAALPKGQWEASR
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
CLGLSFHQTLFRVIAPQAMRIAIAPTVGFSVQVIKGTALASIIGFVELTKAGTMLNNVTY
HHCHHHHHHHHHHHCCHHHEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
QPFKVFGLVALGYFLMCYPLSRYSHYLEKKFHAIDHH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFTDWDIIRNLLLAARWTLLLSLTAFFGGTLVTLPLMLMRLSHWRWAARFVRLYTELFQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTPLLMQLFLAFFGLALFGIDVSPWTAAAMALTLFTSAFLVDIWCGSIAALPKGQWEASR
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
CLGLSFHQTLFRVIAPQAMRIAIAPTVGFSVQVIKGTALASIIGFVELTKAGTMLNNVTY
HHCHHHHHHHHHHHCCHHHEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
QPFKVFGLVALGYFLMCYPLSRYSHYLEKKFHAIDHH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]