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The map label for this gene is mtnC [H]

Identifier: 170025537

GI number: 170025537

Start: 3640684

End: 3641373

Strand: Reverse

Name: mtnC [H]

Synonym: YPK_3320

Alternate gene names: 170025537

Gene position: 3641373-3640684 (Counterclockwise)

Preceding gene: 170025538

Following gene: 170025536

Centisome position: 77.65

GC content: 48.7

Gene sequence:

>690_bases
ATGATTCAGGCGATTGTTACCGATATTGAAGGCACCACCACTGACATCCGTTTTGTCCATCAAGTGCTGTTTCCTTATGC
CCGTGAGCGGTTGACACCTTTCTTACGTGCGCATCAGCAGGACGACGATATCGCTGCTCTACTGGTCGATTTACGCCGCG
AAATTGCTCAACCGGATGCCGATATTGAAACATTGATTACCGTTTTGCATGGTTTTATGGACGAAGACCGCAAATCTACC
GTATTGAAGGCCATTCAAGGCATTATCTGGCGCACGGGTTACTTGCAAGCGGATTTTCGTGGCCACGTGTATCCGGAAGT
TGCCCAACAACTGGCGGATTGGCACCAACAGGGGCTGAAGTTGTATGTCTATTCTTCTGGTTCAGTTGCGGCACAGAAGT
TGTTATTTGGCTACAGCGATGCTGGGGATTTATGCCCGCTGTTCAGTGGCTACTTTGATACCCATGTGGGGGCAAAACGA
GACGTGAGCGCTTATCAGAAGATTGCCAACCAACTGGGTATTGCGCCGCAGGCACTGCTATTTTTATCCGATATTCGCCA
AGAACTGGATGCCGCACAGCTGGCTGGCTGGCATACCTGCCAGTTGATTCGTGATCTACCCGATAATGACAGCGCTCATC
CACAAGTTAATCGTTTTGATCAGATTGTTTTAAGTCTGTTTACTGAATGA

Upstream 100 bases:

>100_bases
AGTTTTTGTTCCAGTGCGAGCTACAACGCCGTTTATTTGATGTGAATTCTAACGTTGATGTAAAACCTAACGTTGACGTA
AATCCTAACGTGGAGGCCAA

Downstream 100 bases:

>100_bases
TTGTTTTAAGTCTGTTTACTGAATGATTATCTTAAGTCCGTTTACCGAATGATTATCTTAAGTTCGTTTACAAAATAATT
GTTCCAGGTCAGTTTACCGC

Product: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MIQAIVTDIEGTTTDIRFVHQVLFPYARERLTPFLRAHQQDDDIAALLVDLRREIAQPDADIETLITVLHGFMDEDRKST
VLKAIQGIIWRTGYLQADFRGHVYPEVAQQLADWHQQGLKLYVYSSGSVAAQKLLFGYSDAGDLCPLFSGYFDTHVGAKR
DVSAYQKIANQLGIAPQALLFLSDIRQELDAAQLAGWHTCQLIRDLPDNDSAHPQVNRFDQIVLSLFTE

Sequences:

>Translated_229_residues
MIQAIVTDIEGTTTDIRFVHQVLFPYARERLTPFLRAHQQDDDIAALLVDLRREIAQPDADIETLITVLHGFMDEDRKST
VLKAIQGIIWRTGYLQADFRGHVYPEVAQQLADWHQQGLKLYVYSSGSVAAQKLLFGYSDAGDLCPLFSGYFDTHVGAKR
DVSAYQKIANQLGIAPQALLFLSDIRQELDAAQLAGWHTCQLIRDLPDNDSAHPQVNRFDQIVLSLFTE
>Mature_229_residues
MIQAIVTDIEGTTTDIRFVHQVLFPYARERLTPFLRAHQQDDDIAALLVDLRREIAQPDADIETLITVLHGFMDEDRKST
VLKAIQGIIWRTGYLQADFRGHVYPEVAQQLADWHQQGLKLYVYSSGSVAAQKLLFGYSDAGDLCPLFSGYFDTHVGAKR
DVSAYQKIANQLGIAPQALLFLSDIRQELDAAQLAGWHTCQLIRDLPDNDSAHPQVNRFDQIVLSLFTE

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family [H]

Homologues:

Organism=Homo sapiens, GI10864017, Length=229, Percent_Identity=34.4978165938865, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI115533232, Length=221, Percent_Identity=38.0090497737557, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320797, Length=201, Percent_Identity=32.8358208955224, Blast_Score=99, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281360080, Length=218, Percent_Identity=43.1192660550459, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24644163, Length=218, Percent_Identity=43.1192660550459, Blast_Score=176, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR010041
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.77 [H]

Molecular weight: Translated: 25828; Mature: 25828

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQAIVTDIEGTTTDIRFVHQVLFPYARERLTPFLRAHQQDDDIAALLVDLRREIAQPDA
CCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
DIETLITVLHGFMDEDRKSTVLKAIQGIIWRTGYLQADFRGHVYPEVAQQLADWHQQGLK
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCE
LYVYSSGSVAAQKLLFGYSDAGDLCPLFSGYFDTHVGAKRDVSAYQKIANQLGIAPQALL
EEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHH
FLSDIRQELDAAQLAGWHTCQLIRDLPDNDSAHPQVNRFDQIVLSLFTE
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIQAIVTDIEGTTTDIRFVHQVLFPYARERLTPFLRAHQQDDDIAALLVDLRREIAQPDA
CCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
DIETLITVLHGFMDEDRKSTVLKAIQGIIWRTGYLQADFRGHVYPEVAQQLADWHQQGLK
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCE
LYVYSSGSVAAQKLLFGYSDAGDLCPLFSGYFDTHVGAKRDVSAYQKIANQLGIAPQALL
EEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHH
FLSDIRQELDAAQLAGWHTCQLIRDLPDNDSAHPQVNRFDQIVLSLFTE
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA