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The map label for this gene is ycgR

Identifier: 170025503

GI number: 170025503

Start: 3596192

End: 3596950

Strand: Reverse

Name: ycgR

Synonym: YPK_3286

Alternate gene names: 170025503

Gene position: 3596950-3596192 (Counterclockwise)

Preceding gene: 170025504

Following gene: 170025502

Centisome position: 76.7

GC content: 42.95

Gene sequence:

>759_bases
ATGGGGACAGTGAGCGAAACGTCTAAAGAGCAATTTGTTAAAAAAAATAAACTAGCGATCTGTGCAATTCTTCGGGATTT
ACAGAAGAACGATACTGCCGTGATGGTTACCCATGCTCGAGGACAATTTATTAGCCGTATTCTGGATATACAGCCTGAGA
CTAATCAGTTTATTTTCGATTTCGGCAGTGTAGAAAACGAAAATGTTTTGGCTCTTGGTGCGGAGCAACTCACGATTATT
GTTGAACCTACGGGTGCCAAAATTGAATTCACCTGTAACAAGCTGAAACATGTCGAATATTTGTCACTACCCGCCTTCAG
TTCTGCCATCCCGGAACAGCTCTATTTCATTCAGAGACGGGAATATTTTCGTGTCAGTATTCCGCAATGGCCAGCTTATT
ATTGTAGTGGGAAATTCCCTGACGGCACTCAGTATAAATATACATTGGCCGACATCTCCTTGGGTGGAATGGGTTTATAT
GCCATGAAAGGTAGCGAATTTCCGCTCCAGGGATGCAGTGTTCTGCGAGATGCAGCGGTAGATTTATGTGGTTTTGGCCT
CTTTAAATTAGATCTGCAATTTATCCGGGCGCTCGATAAACAAGTGGTTAATAACAAGGGCGAAACGCTGACAGTGCAAC
GTTTGAGTTTTAAATTCTTGCGCTTAAGTCCTATTCAAGAGAAAGGCTTACAGCGAGCCATTTTTGAACTGGAAAAACAG
CAAACAGCTAAGGCGAGGAAATTTCAGGAAGGCCTGTAG

Upstream 100 bases:

>100_bases
AAACATTTAAGTAATTCTGTTAGTTGCCGATAACCTCTTTGTTATTTATACATTTTTGATGATAATCTGAGCAGATAGAC
TGATAAATTAAGAATAGGGA

Downstream 100 bases:

>100_bases
CCTCACTATATTCTGTAGCTTCACTCTATAGAGTAGCGGTCTGTCGCTTGTATGATGCGTTTTATCATTATTTACAAGCC
CACAGGGAGCGCCTCTGAGG

Product: YcgR family protein

Products: NA

Alternate protein names: Cyclic di-GMP binding protein YcgR

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MGTVSETSKEQFVKKNKLAICAILRDLQKNDTAVMVTHARGQFISRILDIQPETNQFIFDFGSVENENVLALGAEQLTII
VEPTGAKIEFTCNKLKHVEYLSLPAFSSAIPEQLYFIQRREYFRVSIPQWPAYYCSGKFPDGTQYKYTLADISLGGMGLY
AMKGSEFPLQGCSVLRDAAVDLCGFGLFKLDLQFIRALDKQVVNNKGETLTVQRLSFKFLRLSPIQEKGLQRAIFELEKQ
QTAKARKFQEGL

Sequences:

>Translated_252_residues
MGTVSETSKEQFVKKNKLAICAILRDLQKNDTAVMVTHARGQFISRILDIQPETNQFIFDFGSVENENVLALGAEQLTII
VEPTGAKIEFTCNKLKHVEYLSLPAFSSAIPEQLYFIQRREYFRVSIPQWPAYYCSGKFPDGTQYKYTLADISLGGMGLY
AMKGSEFPLQGCSVLRDAAVDLCGFGLFKLDLQFIRALDKQVVNNKGETLTVQRLSFKFLRLSPIQEKGLQRAIFELEKQ
QTAKARKFQEGL
>Mature_251_residues
GTVSETSKEQFVKKNKLAICAILRDLQKNDTAVMVTHARGQFISRILDIQPETNQFIFDFGSVENENVLALGAEQLTIIV
EPTGAKIEFTCNKLKHVEYLSLPAFSSAIPEQLYFIQRREYFRVSIPQWPAYYCSGKFPDGTQYKYTLADISLGGMGLYA
MKGSEFPLQGCSVLRDAAVDLCGFGLFKLDLQFIRALDKQVVNNKGETLTVQRLSFKFLRLSPIQEKGLQRAIFELEKQQ
TAKARKFQEGL

Specific function: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility

COG id: COG5581

COG function: function code M; Predicted glycosyltransferase

Gene ontology:

Cell location: Bacterial flagellum basal body

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain

Homologues:

Organism=Escherichia coli, GI1787443, Length=241, Percent_Identity=41.0788381742739, Blast_Score=198, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCGR_YERPS (Q66DY7)

Other databases:

- EMBL:   BX936398
- RefSeq:   YP_069447.1
- ProteinModelPortal:   Q66DY7
- GeneID:   2953391
- GenomeReviews:   BX936398_GR
- KEGG:   yps:YPTB0906
- HOGENOM:   HBG436770
- OMA:   AGLHEGM
- ProtClustDB:   CLSK889436
- BioCyc:   YPSE273123:YPTB0906-MONOMER
- HAMAP:   MF_01457
- InterPro:   IPR009875
- InterPro:   IPR009926

Pfam domain/function: PF07238 PilZ; PF07317 YcgR

EC number: NA

Molecular weight: Translated: 28500; Mature: 28369

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTVSETSKEQFVKKNKLAICAILRDLQKNDTAVMVTHARGQFISRILDIQPETNQFIFD
CCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCCEEEEE
FGSVENENVLALGAEQLTIIVEPTGAKIEFTCNKLKHVEYLSLPAFSSAIPEQLYFIQRR
ECCCCCCCEEEECCCEEEEEECCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHCC
EYFRVSIPQWPAYYCSGKFPDGTQYKYTLADISLGGMGLYAMKGSEFPLQGCSVLRDAAV
CEEEEECCCCCCEEECCCCCCCCCEEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHH
DLCGFGLFKLDLQFIRALDKQVVNNKGETLTVQRLSFKFLRLSPIQEKGLQRAIFELEKQ
HHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHEEEEEEECCHHHHHHHHHHHHHHHH
QTAKARKFQEGL
HHHHHHHHHHCC
>Mature Secondary Structure 
GTVSETSKEQFVKKNKLAICAILRDLQKNDTAVMVTHARGQFISRILDIQPETNQFIFD
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCCEEEEE
FGSVENENVLALGAEQLTIIVEPTGAKIEFTCNKLKHVEYLSLPAFSSAIPEQLYFIQRR
ECCCCCCCEEEECCCEEEEEECCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHCC
EYFRVSIPQWPAYYCSGKFPDGTQYKYTLADISLGGMGLYAMKGSEFPLQGCSVLRDAAV
CEEEEECCCCCCEEECCCCCCCCCEEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHH
DLCGFGLFKLDLQFIRALDKQVVNNKGETLTVQRLSFKFLRLSPIQEKGLQRAIFELEKQ
HHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHEEEEEEECCHHHHHHHHHHHHHHHH
QTAKARKFQEGL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA