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The map label for this gene is malZ [H]

Identifier: 170025488

GI number: 170025488

Start: 3575590

End: 3577419

Strand: Reverse

Name: malZ [H]

Synonym: YPK_3271

Alternate gene names: 170025488

Gene position: 3577419-3575590 (Counterclockwise)

Preceding gene: 170025489

Following gene: 170025487

Centisome position: 76.29

GC content: 50.33

Gene sequence:

>1830_bases
ATGCTTAGTGGTTGGCACCTTCCGGTCTCGCCTTTTGTTCGTTTGGCAGACGACGCATTACATATCACGCTCTGGTTGCA
AGGTGATAGTTTACCTGCGCAAGTCTTTCTGCGTTGTGAGCCAGATAATGAAGAGTGGCTGCTCACTATGGAGGGGCATG
AGAGCCATGATCGTTGGCGCTATAGCGTTTCTTTACCGTTATATGAGGGGCAGCCAACCCGGCGCTACTGCTTCAAACTA
TTATGGGATGACCACCAACAGTGGTTTGGCCCGTTGGGGTTCTCGGTGATTCCTCCAGCACAGTTGGCACAGTTTGCTGT
AGATGTACCCGATAGCGGGCCTGATTGGGTCGCGGACCAAGTTTTTTATCAGATCTTCCCCGATCGCTTTGCCAGTAGTC
AGGCAGATCATGGTGTGCAGGAGGGGAGTTATATTCATCATGCGGCCGGTTGCCCGGTATCTCGCCGTGAGTGGCAGCAG
CCATTGGATGATGTGCATGCCGCATCGACATTTTATGGTGGCGATCTGGCCGGTATTAGTCAGAAAATCCCTTACTTTCA
ACAACTGGGGGTTACGGCGCTGTATTTGAACCCTATTTTTACCGCTCCCAGTGTGCATAAATATGATACTGAAGATTATT
ATCAGGTTGATCCCTACTTGGGGGGAGAGCGTGATTTCTTGCAATTGCGAGCCGCTACCCGTGAAGTAGGAATAAAGTTG
GTGCTCGATGGCGTGTTTAACCACACGGGTGATTCTCATCGCTGGTTTGATCGCTATCAACAAGGGGAAAACGGCGCCTG
CCATCACGAAGATTCGCCTTATCGTGGTTGGTTTACGTTCCTCCCTGATGGACGAGCATTAGATTGGAAAGGTAATGCCA
GTTTGCCAAAACTTAATTTTGCCAATGAAGAGGTCGCTGAACGAATCTATCGCAGTGATGACAGCGTCGTGCGTTATTGG
TTACGGCCACCATACAGTATTGATGGCTGGCGTCTGGATGTCGTACACATGCTCGGGGAAGATGGCGGCGCTAAAGGGAA
TTTGCACCATCTGCACGGTATCTATCAGGCAGCAAAAGAAGAAAATCCGCAGGCTTATATTCTGGGCGAACATTTTGGCG
ATGCACGTAATTGGTTGCACGCTGGCGTGGAAGACGCGGCAATGAATTATATGGGTTTTGCTTTGCCGGTCCGCAGTTTT
CTAGCCGAGCTAGATGTGGCTTGCCATCCTATAAAATTGGATGCTGCGGATTGCGCCTACTGGATGGATGAGTACCGCGC
AGGATTGCCCCATAGCCAGCAACTCCGTTTATTTAATCAATTAGATAGCCATGATACTGCCCGTTTTCTTACCTTATTAA
AGGGTGATAAAACCCGTATGCAAATGGCGCTGATATGGTTGTTTAGTTGGATTGGTGTGCCTTGCCTATTTTATGGTGAT
GAGATTGGGCTGGATGGCGGGAATGATCCGTTCTGCCGCAAACCGTTCCCATGGGATGAGGCTCAGTGGGATCATGACCT
ATTATCACTGTGTCAACGTATGGCGGCTTTACGCCACAAAAGCATAGCGTTGCGGCGCGGGGGGTGTCAGGTGATCCATG
CCAGTGGTGATTCCCTGGTCTTTATTCGTAGCTATCAAACTGAGCGTGTGATGGTGGCGATACAACGTTCCGATGATGCG
GATATTTTCCTGCCCGCCTCTCCTTTACTCAATGTGGCTGAGTGGCAGCGTCTGGAAGGTGGAGGAGACCTGGCTGTCAG
TGAGACTGGGGTAAACATGGGGCTGGAGGGTAAGAGTGTTACCTTGTGGTGTGGTGTTGGTGAGTGCTAA

Upstream 100 bases:

>100_bases
GGCGTTAGTGTCTGCATCAGGTTAATGTCTGTAGCAGGTTAGTGTTTGCACAAAGTTAATGTCTGCACAGGAATGGTTTT
GGTTAAAGCAGGAGAATTTT

Downstream 100 bases:

>100_bases
CTTGCAAAAGGCGCGGTGGCGGATAACTCACCAGAGCGGCTCAGGGATAATAATTCAGTGATAACTGAGCTGTTTTTTCG
CTCCAGTAAGATAATATTTC

Product: maltodextrin glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase [H]

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MLSGWHLPVSPFVRLADDALHITLWLQGDSLPAQVFLRCEPDNEEWLLTMEGHESHDRWRYSVSLPLYEGQPTRRYCFKL
LWDDHQQWFGPLGFSVIPPAQLAQFAVDVPDSGPDWVADQVFYQIFPDRFASSQADHGVQEGSYIHHAAGCPVSRREWQQ
PLDDVHAASTFYGGDLAGISQKIPYFQQLGVTALYLNPIFTAPSVHKYDTEDYYQVDPYLGGERDFLQLRAATREVGIKL
VLDGVFNHTGDSHRWFDRYQQGENGACHHEDSPYRGWFTFLPDGRALDWKGNASLPKLNFANEEVAERIYRSDDSVVRYW
LRPPYSIDGWRLDVVHMLGEDGGAKGNLHHLHGIYQAAKEENPQAYILGEHFGDARNWLHAGVEDAAMNYMGFALPVRSF
LAELDVACHPIKLDAADCAYWMDEYRAGLPHSQQLRLFNQLDSHDTARFLTLLKGDKTRMQMALIWLFSWIGVPCLFYGD
EIGLDGGNDPFCRKPFPWDEAQWDHDLLSLCQRMAALRHKSIALRRGGCQVIHASGDSLVFIRSYQTERVMVAIQRSDDA
DIFLPASPLLNVAEWQRLEGGGDLAVSETGVNMGLEGKSVTLWCGVGEC

Sequences:

>Translated_609_residues
MLSGWHLPVSPFVRLADDALHITLWLQGDSLPAQVFLRCEPDNEEWLLTMEGHESHDRWRYSVSLPLYEGQPTRRYCFKL
LWDDHQQWFGPLGFSVIPPAQLAQFAVDVPDSGPDWVADQVFYQIFPDRFASSQADHGVQEGSYIHHAAGCPVSRREWQQ
PLDDVHAASTFYGGDLAGISQKIPYFQQLGVTALYLNPIFTAPSVHKYDTEDYYQVDPYLGGERDFLQLRAATREVGIKL
VLDGVFNHTGDSHRWFDRYQQGENGACHHEDSPYRGWFTFLPDGRALDWKGNASLPKLNFANEEVAERIYRSDDSVVRYW
LRPPYSIDGWRLDVVHMLGEDGGAKGNLHHLHGIYQAAKEENPQAYILGEHFGDARNWLHAGVEDAAMNYMGFALPVRSF
LAELDVACHPIKLDAADCAYWMDEYRAGLPHSQQLRLFNQLDSHDTARFLTLLKGDKTRMQMALIWLFSWIGVPCLFYGD
EIGLDGGNDPFCRKPFPWDEAQWDHDLLSLCQRMAALRHKSIALRRGGCQVIHASGDSLVFIRSYQTERVMVAIQRSDDA
DIFLPASPLLNVAEWQRLEGGGDLAVSETGVNMGLEGKSVTLWCGVGEC
>Mature_609_residues
MLSGWHLPVSPFVRLADDALHITLWLQGDSLPAQVFLRCEPDNEEWLLTMEGHESHDRWRYSVSLPLYEGQPTRRYCFKL
LWDDHQQWFGPLGFSVIPPAQLAQFAVDVPDSGPDWVADQVFYQIFPDRFASSQADHGVQEGSYIHHAAGCPVSRREWQQ
PLDDVHAASTFYGGDLAGISQKIPYFQQLGVTALYLNPIFTAPSVHKYDTEDYYQVDPYLGGERDFLQLRAATREVGIKL
VLDGVFNHTGDSHRWFDRYQQGENGACHHEDSPYRGWFTFLPDGRALDWKGNASLPKLNFANEEVAERIYRSDDSVVRYW
LRPPYSIDGWRLDVVHMLGEDGGAKGNLHHLHGIYQAAKEENPQAYILGEHFGDARNWLHAGVEDAAMNYMGFALPVRSF
LAELDVACHPIKLDAADCAYWMDEYRAGLPHSQQLRLFNQLDSHDTARFLTLLKGDKTRMQMALIWLFSWIGVPCLFYGD
EIGLDGGNDPFCRKPFPWDEAQWDHDLLSLCQRMAALRHKSIALRRGGCQVIHASGDSLVFIRSYQTERVMVAIQRSDDA
DIFLPASPLLNVAEWQRLEGGGDLAVSETGVNMGLEGKSVTLWCGVGEC

Specific function: May play a role in regulating the intracellular level of maltotriose. Cleaves glucose from the reducing end of maltotriose and longer maltodextrins with a chain length of up to 7 glucose units [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=377, Percent_Identity=24.6684350132626, Blast_Score=83, Evalue=7e-16,
Organism=Escherichia coli, GI1786604, Length=608, Percent_Identity=57.5657894736842, Blast_Score=726, Evalue=0.0,
Organism=Escherichia coli, GI1790687, Length=189, Percent_Identity=29.6296296296296, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789995, Length=116, Percent_Identity=31.8965517241379, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322245, Length=202, Percent_Identity=30.6930693069307, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321726, Length=256, Percent_Identity=26.5625, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322241, Length=265, Percent_Identity=25.2830188679245, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322021, Length=265, Percent_Identity=25.2830188679245, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324416, Length=265, Percent_Identity=25.2830188679245, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321731, Length=267, Percent_Identity=24.3445692883895, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319776, Length=267, Percent_Identity=24.3445692883895, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24586589, Length=199, Percent_Identity=33.6683417085427, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24583747, Length=257, Percent_Identity=29.5719844357977, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24583749, Length=257, Percent_Identity=29.5719844357977, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24586587, Length=198, Percent_Identity=30.3030303030303, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24586599, Length=566, Percent_Identity=22.9681978798587, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583745, Length=433, Percent_Identity=24.0184757505774, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24586591, Length=198, Percent_Identity=30.3030303030303, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24586593, Length=257, Percent_Identity=28.7937743190661, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24586597, Length=250, Percent_Identity=29.2, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221330053, Length=254, Percent_Identity=26.7716535433071, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45549022, Length=193, Percent_Identity=29.5336787564767, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756
- InterPro:   IPR017069 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 69065; Mature: 69065

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGWHLPVSPFVRLADDALHITLWLQGDSLPAQVFLRCEPDNEEWLLTMEGHESHDRWR
CCCCCCCCHHHHHHHCCCEEEEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCCCCCEE
YSVSLPLYEGQPTRRYCFKLLWDDHQQWFGPLGFSVIPPAQLAQFAVDVPDSGPDWVADQ
EEEEEEEECCCCHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHEEECCCCCCCHHHHH
VFYQIFPDRFASSQADHGVQEGSYIHHAAGCPVSRREWQQPLDDVHAASTFYGGDLAGIS
HHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHCCHHHHHHHHHCCCCCHHHHH
QKIPYFQQLGVTALYLNPIFTAPSVHKYDTEDYYQVDPYLGGERDFLQLRAATREVGIKL
HCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCEEE
VLDGVFNHTGDSHRWFDRYQQGENGACHHEDSPYRGWFTFLPDGRALDWKGNASLPKLNF
EEEHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCCCCCCCCC
ANEEVAERIYRSDDSVVRYWLRPPYSIDGWRLDVVHMLGEDGGAKGNLHHLHGIYQAAKE
CCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHC
ENPQAYILGEHFGDARNWLHAGVEDAAMNYMGFALPVRSFLAELDVACHPIKLDAADCAY
CCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHH
WMDEYRAGLPHSQQLRLFNQLDSHDTARFLTLLKGDKTRMQMALIWLFSWIGVPCLFYGD
HHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECC
EIGLDGGNDPFCRKPFPWDEAQWDHDLLSLCQRMAALRHKSIALRRGGCQVIHASGDSLV
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCEE
FIRSYQTERVMVAIQRSDDADIFLPASPLLNVAEWQRLEGGGDLAVSETGVNMGLEGKSV
EEEECCCCEEEEEEECCCCCCEEECCHHHCCHHHHHHCCCCCCEEEEECCCCCCCCCCEE
TLWCGVGEC
EEEEECCCC
>Mature Secondary Structure
MLSGWHLPVSPFVRLADDALHITLWLQGDSLPAQVFLRCEPDNEEWLLTMEGHESHDRWR
CCCCCCCCHHHHHHHCCCEEEEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCCCCCEE
YSVSLPLYEGQPTRRYCFKLLWDDHQQWFGPLGFSVIPPAQLAQFAVDVPDSGPDWVADQ
EEEEEEEECCCCHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHEEECCCCCCCHHHHH
VFYQIFPDRFASSQADHGVQEGSYIHHAAGCPVSRREWQQPLDDVHAASTFYGGDLAGIS
HHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHCCHHHHHHHHHCCCCCHHHHH
QKIPYFQQLGVTALYLNPIFTAPSVHKYDTEDYYQVDPYLGGERDFLQLRAATREVGIKL
HCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCEEE
VLDGVFNHTGDSHRWFDRYQQGENGACHHEDSPYRGWFTFLPDGRALDWKGNASLPKLNF
EEEHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCCCCCCCCC
ANEEVAERIYRSDDSVVRYWLRPPYSIDGWRLDVVHMLGEDGGAKGNLHHLHGIYQAAKE
CCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHC
ENPQAYILGEHFGDARNWLHAGVEDAAMNYMGFALPVRSFLAELDVACHPIKLDAADCAY
CCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHH
WMDEYRAGLPHSQQLRLFNQLDSHDTARFLTLLKGDKTRMQMALIWLFSWIGVPCLFYGD
HHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECC
EIGLDGGNDPFCRKPFPWDEAQWDHDLLSLCQRMAALRHKSIALRRGGCQVIHASGDSLV
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCEE
FIRSYQTERVMVAIQRSDDADIFLPASPLLNVAEWQRLEGGGDLAVSETGVNMGLEGKSV
EEEECCCCEEEEEEECCCCCCEEECCHHHCCHHHHHHCCCCCCEEEEECCCCCCCCCCEE
TLWCGVGEC
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1918057; 9278503; 1706703 [H]