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The map label for this gene is fur [H]

Identifier: 170025213

GI number: 170025213

Start: 3285348

End: 3285794

Strand: Direct

Name: fur [H]

Synonym: YPK_2991

Alternate gene names: 170025213

Gene position: 3285348-3285794 (Clockwise)

Preceding gene: 170025212

Following gene: 170025219

Centisome position: 70.06

GC content: 42.73

Gene sequence:

>447_bases
ATGACTGACAACAACAAAGCCTTAAAAAACGCTGGCCTTAAAGTCACACTCCCCCGGCTTAAAATTCTGGAAGTGTTGCA
AAATCCTGCGTGTCACCACGTCAGCGCGGAAGATCTTTATAAAAAACTGATCGATATTGGTGAAGAGATTGGCTTAGCAA
CGGTTTACCGTGTTCTGAACCAATTTGATGATGCTGGTATTGTTACCCGCCACAATTTCGAAGGGGGTAAATCAGTTTTT
GAGCTGACTCAACAACATCACCACGATCACCTAATTTGCCTGGATTGCGGCAAAGTGATCGAGTTTAGCAACGAATCCAT
TGAATCACTTCAACGTGAAATTGCTAAACAACATGGCATCAAGCTGACTAATCATAGCCTGTATTTATACGGTCACTGTG
AAACCGGCAATTGCCGTGAAGATGAGTCTGCACACAGTAAAAGATAA

Upstream 100 bases:

>100_bases
CTAGCAGCTCTATAATAAGACGCAATTATGATTATTGCGCCACGGATGTCATAGGCTAAACAGCCTTAATTTGAATCGAT
TGTAACAGGACTGAATCCGC

Downstream 100 bases:

>100_bases
TATCGTTTTATCGCATTACTCTTATAAAGATTTTAAGCACTGCTAGGTTTACTGTTTATGTTTGATAAGGCCATGTCACT
AGAGCGTTACACATCAGGCT

Product: ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MTDNNKALKNAGLKVTLPRLKILEVLQNPACHHVSAEDLYKKLIDIGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVF
ELTQQHHHDHLICLDCGKVIEFSNESIESLQREIAKQHGIKLTNHSLYLYGHCETGNCREDESAHSKR

Sequences:

>Translated_148_residues
MTDNNKALKNAGLKVTLPRLKILEVLQNPACHHVSAEDLYKKLIDIGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVF
ELTQQHHHDHLICLDCGKVIEFSNESIESLQREIAKQHGIKLTNHSLYLYGHCETGNCREDESAHSKR
>Mature_147_residues
TDNNKALKNAGLKVTLPRLKILEVLQNPACHHVSAEDLYKKLIDIGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFE
LTQQHHHDHLICLDCGKVIEFSNESIESLQREIAKQHGIKLTNHSLYLYGHCETGNCREDESAHSKR

Specific function: Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=148, Percent_Identity=85.8108108108108, Blast_Score=265, Evalue=1e-72,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16743; Mature: 16612

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNNKALKNAGLKVTLPRLKILEVLQNPACHHVSAEDLYKKLIDIGEEIGLATVYRVLN
CCCCCHHHHHCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSNESIESLQREIAKQHGI
HCCCCCCEEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHCC
KLTNHSLYLYGHCETGNCREDESAHSKR
EEECCEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDNNKALKNAGLKVTLPRLKILEVLQNPACHHVSAEDLYKKLIDIGEEIGLATVYRVLN
CCCCHHHHHCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSNESIESLQREIAKQHGI
HCCCCCCEEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHCC
KLTNHSLYLYGHCETGNCREDESAHSKR
EEECCEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406286; 11586360; 12142430 [H]