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The map label for this gene is 170025058

Identifier: 170025058

GI number: 170025058

Start: 3118427

End: 3119416

Strand: Reverse

Name: 170025058

Synonym: YPK_2834

Alternate gene names: NA

Gene position: 3119416-3118427 (Counterclockwise)

Preceding gene: 170025061

Following gene: 170025056

Centisome position: 66.52

GC content: 49.49

Gene sequence:

>990_bases
ATGGCGAAGAAAAACCCCTATTATGATGCCAGCAAGCCACATCACACAGAGTTTGGATTTCAGAATATAGAACCGGTTGT
TCATCATCCGCAGGATTTGAAACGCTGGCGTGAAGAGAGAAAGCGCCAGTCGCTGCCTAAGCCGCCTCAGCAGGGCTACC
CGCAGTTCGTTACAGATTGGTGGCAACAAGCTGACTTTTCAGGGCAGCAAGATGCGTTGTGGTGGCTTGGCCATGCTTCA
TTATTGTTACGTATCAGTGGGCAGGCAGTGTTGTTTGACCCTGTGCTTTCAAGCCGGGTTTCACCGGTTAATTTTTATGG
CCCACAGCGCAAAACACCAATACCCGCCAGCGTACAGCAACTGCCCGATATTGATGTGATCGTGATCTCTCATAATCATT
ACGATCACTTGGATGTCACGACTATCACGCAATTATTGCGCCGTTTCCCTGACGTGGTGTTTTTGGTCCCATTAGGGCTG
AAAAACTGGTTGCGGCAGCATGGTGCTCGCCATGTTCATGAGTTGGATTGGTGGGATCAACGGCTCGTCGCTGACTTTGA
GTTCCATTGTGTGCCCGCCCGTCATTGGAGTATGCGCACTCCTTGGGATCGGAATCACAGTTTGTGGTCTGGCTGGGTAG
TGAAGCGGGGCGAAGTTAACTTTTATTTCAGTGGTGATACTGGCTATTGCCAGCAATTACTGGATATCGGTGAGGCACTG
GGGCCATTCAATTATGCGGCACTGCCAATTGGTGCTTATGCACCACGCTGGTTTATGCAGGCGCAACATATGGATCCACA
ACAATCGGTGCAATTGTTTCAAAAATTACACCAACCGGTGACGATCCCGATTCATTGGGGGGTCTTTGAACTGGCTGATG
AGCCATTGGATGAACCACCAGAACAACTTCAACAGGCGTTAACCGATGCCGGAGTGGCGCACAATAAATTCGTACCAATT
AAAATAGGTGCACGGATCATACTGGAATAG

Upstream 100 bases:

>100_bases
CCCTGTGAGAAGGATCACCTTTGTTCTCATGTGATGTGTTACAGAAAATCCCAATTAATGTATGTTGGCTGCAACAGCGG
TTGGCAGTAAAGGACGTAAA

Downstream 100 bases:

>100_bases
TCACGTTCCAGCGGGTGGATGAATAACCTGCTGGAACTGAATGACGGCGGTTCTGGTTGATAGCAGCAGCGCGTTAGATC
TTAAATTGATTAACGGTATC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MAKKNPYYDASKPHHTEFGFQNIEPVVHHPQDLKRWREERKRQSLPKPPQQGYPQFVTDWWQQADFSGQQDALWWLGHAS
LLLRISGQAVLFDPVLSSRVSPVNFYGPQRKTPIPASVQQLPDIDVIVISHNHYDHLDVTTITQLLRRFPDVVFLVPLGL
KNWLRQHGARHVHELDWWDQRLVADFEFHCVPARHWSMRTPWDRNHSLWSGWVVKRGEVNFYFSGDTGYCQQLLDIGEAL
GPFNYAALPIGAYAPRWFMQAQHMDPQQSVQLFQKLHQPVTIPIHWGVFELADEPLDEPPEQLQQALTDAGVAHNKFVPI
KIGARIILE

Sequences:

>Translated_329_residues
MAKKNPYYDASKPHHTEFGFQNIEPVVHHPQDLKRWREERKRQSLPKPPQQGYPQFVTDWWQQADFSGQQDALWWLGHAS
LLLRISGQAVLFDPVLSSRVSPVNFYGPQRKTPIPASVQQLPDIDVIVISHNHYDHLDVTTITQLLRRFPDVVFLVPLGL
KNWLRQHGARHVHELDWWDQRLVADFEFHCVPARHWSMRTPWDRNHSLWSGWVVKRGEVNFYFSGDTGYCQQLLDIGEAL
GPFNYAALPIGAYAPRWFMQAQHMDPQQSVQLFQKLHQPVTIPIHWGVFELADEPLDEPPEQLQQALTDAGVAHNKFVPI
KIGARIILE
>Mature_328_residues
AKKNPYYDASKPHHTEFGFQNIEPVVHHPQDLKRWREERKRQSLPKPPQQGYPQFVTDWWQQADFSGQQDALWWLGHASL
LLRISGQAVLFDPVLSSRVSPVNFYGPQRKTPIPASVQQLPDIDVIVISHNHYDHLDVTTITQLLRRFPDVVFLVPLGLK
NWLRQHGARHVHELDWWDQRLVADFEFHCVPARHWSMRTPWDRNHSLWSGWVVKRGEVNFYFSGDTGYCQQLLDIGEALG
PFNYAALPIGAYAPRWFMQAQHMDPQQSVQLFQKLHQPVTIPIHWGVFELADEPLDEPPEQLQQALTDAGVAHNKFVPIK
IGARIILE

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=253, Percent_Identity=42.6877470355731, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI170932481, Length=253, Percent_Identity=42.6877470355731, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17543102, Length=274, Percent_Identity=39.4160583941606, Blast_Score=213, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI17543100, Length=274, Percent_Identity=39.4160583941606, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI25148824, Length=274, Percent_Identity=39.4160583941606, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17543104, Length=262, Percent_Identity=39.3129770992366, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6325154, Length=252, Percent_Identity=31.3492063492063, Blast_Score=138, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38223; Mature: 38092

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKNPYYDASKPHHTEFGFQNIEPVVHHPQDLKRWREERKRQSLPKPPQQGYPQFVTDW
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
WQQADFSGQQDALWWLGHASLLLRISGQAVLFDPVLSSRVSPVNFYGPQRKTPIPASVQQ
HHHCCCCCCCCCEEEHHHEEEEEEECCCEEEECHHHHCCCCCCCCCCCCCCCCCCHHHHH
LPDIDVIVISHNHYDHLDVTTITQLLRRFPDVVFLVPLGLKNWLRQHGARHVHELDWWDQ
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHH
RLVADFEFHCVPARHWSMRTPWDRNHSLWSGWVVKRGEVNFYFSGDTGYCQQLLDIGEAL
HHHHCCEEEEEECCCCCCCCCCCCCCCCEECEEEEECCEEEEECCCHHHHHHHHHHHHHH
GPFNYAALPIGAYAPRWFMQAQHMDPQQSVQLFQKLHQPVTIPIHWGVFELADEPLDEPP
CCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCHHHHCCCCCCCCH
EQLQQALTDAGVAHNKFVPIKIGARIILE
HHHHHHHHHCCCCCCCEEEEEECCEEECC
>Mature Secondary Structure 
AKKNPYYDASKPHHTEFGFQNIEPVVHHPQDLKRWREERKRQSLPKPPQQGYPQFVTDW
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
WQQADFSGQQDALWWLGHASLLLRISGQAVLFDPVLSSRVSPVNFYGPQRKTPIPASVQQ
HHHCCCCCCCCCEEEHHHEEEEEEECCCEEEECHHHHCCCCCCCCCCCCCCCCCCHHHHH
LPDIDVIVISHNHYDHLDVTTITQLLRRFPDVVFLVPLGLKNWLRQHGARHVHELDWWDQ
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHH
RLVADFEFHCVPARHWSMRTPWDRNHSLWSGWVVKRGEVNFYFSGDTGYCQQLLDIGEAL
HHHHCCEEEEEECCCCCCCCCCCCCCCCEECEEEEECCEEEEECCCHHHHHHHHHHHHHH
GPFNYAALPIGAYAPRWFMQAQHMDPQQSVQLFQKLHQPVTIPIHWGVFELADEPLDEPP
CCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCHHHHCCCCCCCCH
EQLQQALTDAGVAHNKFVPIKIGARIILE
HHHHHHHHHCCCCCCCEEEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]