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The map label for this gene is xylB [H]

Identifier: 170024995

GI number: 170024995

Start: 3056244

End: 3057779

Strand: Reverse

Name: xylB [H]

Synonym: YPK_2770

Alternate gene names: 170024995

Gene position: 3057779-3056244 (Counterclockwise)

Preceding gene: 170024996

Following gene: 170024994

Centisome position: 65.21

GC content: 58.72

Gene sequence:

>1536_bases
ATGCAGGCGCTTTTGGGCATTGATATCGGCACCTCGGGGTGTAAGGCGTTGCTGATCGGTATCGATGGTGCGGTGATCGC
CGCCGATACCGCGAGTTATCCATTATCTCAACCCCAACTCGGGTGGGCTGAGCAAGATCCTGAGCTGTGGATCGAGGGGG
CGCGTCGAGCCGTGGCAGGAGCATTGGCTAAAGCGCCAACGCTGGAGTTGCTCTGCGTGGGGCTATCCGGGCAAATGCAT
GGGCTGGTATCACTTGATGCTGGGCATCAGGTGTTGCGCCCGGCGATCCTCTGGAACGACCAACGCAATAGTGCTGAATG
CGAGCAGATTACCGAGGCAGCGGGGGGGCTAAAAGGATTGTTGGCGGCGACTAACAACCGAATGTTGGTGGGCTACACCG
GTGGCAAGATTGTGTGGATGCAGCAGCATGAGCCTGATCTCTTCGCTCGCATGACCACGGTACTGAACCCCAAAGACTAC
TTGCGGCTGCGTTTGACGGGGGAGGTCGCCACTGAAGTTTCGGATGCCTCGGGGACCGGGCTTTTCGATGTACGTGCACG
CCAGTGGGCGAGTGATCTTATTGAGAACGTGGGGATTGACCGCGCTTTACTGCCCCCCGTATTTGAATCGCAGGTGATCT
CTGGCCAGGTCTCAGCGGTGGGGGCCGAGCTATTCGGTATTCCCAAAGGCACGCCCGTTGCTGGTGGTGGCGGTGATGCT
GTGATACAGACCTTCGGTTCTGGGGTGATCGCTCCGGGTGAGTTACAAACCACCATCGGCACGGCGGGCATCCTTGCAGC
GGCATTGGATACACCACAGGCGAACCCCGACGGGCGGTTACAGGTTTTTTGTCATGTTGTGGCTGATAAATGGCACTGCA
TGGGGGTCTCGCTGAACGCTGGCGGCGCGATGAGTTGGTTTCGTGACACGTTTTATGTGGGTGTTAATGCGGCGGTTCCT
TCTTTTGATCAGTTCACACCTTCTTTTGAGCAGATCGTTGCTGAGGCGGCAGCCAGCCCGGCAGGGGCGCGCGGTCTGCT
GTTCTTACCTTATCTGAATGGTGAACGTTGCCCTCATCCTGATCCTGCGGCGCGCGGTGCCTTCATTGGTCTGACAGCCT
GCCACAATCGTGGCGATGTGGCACGTGCAGTCATGGAGGGGGTGGTCCACGCCCTTGTGGATATGCACACCTTGATGAAG
CCATTGGGCATCAATGGGCGGGTTGTAAAAACATCCGGTGGCGGTGCACGTTCGCCCCTTTGGCGGCAGATGCAGGCAGA
TATTTTCGGCTGTGATGTCCTTACCACAAAAGGGGCTGCTGAAGGCGCCGCATTCGGTGCCGCGCTGGTGGCGGGATTGG
CTATCGGGGTTTGGCCCGATGCGACGAGCGCGACGGCGAACTGCCGTATCATCACGCGCGAACCCCCCAATCCCGCAACC
GCGGCGGTTGTTGCTGAGGCCCAACGCATTTACCGTACTCTTTACCCGGCGCTGAGAGAAACCTTCGCAGAACTTGGCGA
CCCCACCTTTATGTAG

Upstream 100 bases:

>100_bases
TAAGCAAAGTGGTGTGGGCTACGAGCATGGCCGTGAGGGGTTGCTGGAGTATTTCAATTTCAAGCACATCCGCTTGTACC
ACGGTATCGGGGACTAAACC

Downstream 100 bases:

>100_bases
TCATGATCAGGAGTCACGCATGAGCAATCAACAAAATGACGCCAAGAGGGCTGCCGCCCGTCGGGTGATTCAGGATTTCG
TGTTCGATGGCATGACGTTG

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWIEGARRAVAGALAKAPTLELLCVGLSGQMH
GLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGLLAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDY
LRLRLTGEVATEVSDASGTGLFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
VIQTFGSGVIAPGELQTTIGTAGILAAALDTPQANPDGRLQVFCHVVADKWHCMGVSLNAGGAMSWFRDTFYVGVNAAVP
SFDQFTPSFEQIVAEAAASPAGARGLLFLPYLNGERCPHPDPAARGAFIGLTACHNRGDVARAVMEGVVHALVDMHTLMK
PLGINGRVVKTSGGGARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITREPPNPAT
AAVVAEAQRIYRTLYPALRETFAELGDPTFM

Sequences:

>Translated_511_residues
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWIEGARRAVAGALAKAPTLELLCVGLSGQMH
GLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGLLAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDY
LRLRLTGEVATEVSDASGTGLFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
VIQTFGSGVIAPGELQTTIGTAGILAAALDTPQANPDGRLQVFCHVVADKWHCMGVSLNAGGAMSWFRDTFYVGVNAAVP
SFDQFTPSFEQIVAEAAASPAGARGLLFLPYLNGERCPHPDPAARGAFIGLTACHNRGDVARAVMEGVVHALVDMHTLMK
PLGINGRVVKTSGGGARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITREPPNPAT
AAVVAEAQRIYRTLYPALRETFAELGDPTFM
>Mature_511_residues
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWIEGARRAVAGALAKAPTLELLCVGLSGQMH
GLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGLLAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDY
LRLRLTGEVATEVSDASGTGLFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
VIQTFGSGVIAPGELQTTIGTAGILAAALDTPQANPDGRLQVFCHVVADKWHCMGVSLNAGGAMSWFRDTFYVGVNAAVP
SFDQFTPSFEQIVAEAAASPAGARGLLFLPYLNGERCPHPDPAARGAFIGLTACHNRGDVARAVMEGVVHALVDMHTLMK
PLGINGRVVKTSGGGARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITREPPNPAT
AAVVAEAQRIYRTLYPALRETFAELGDPTFM

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI88196792, Length=493, Percent_Identity=24.7464503042596, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI41393575, Length=430, Percent_Identity=25.5813953488372, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI42794763, Length=449, Percent_Identity=24.4988864142539, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI189409120, Length=449, Percent_Identity=24.7216035634744, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4504007, Length=449, Percent_Identity=24.7216035634744, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI18860918, Length=466, Percent_Identity=23.175965665236, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789987, Length=501, Percent_Identity=36.7265469061876, Blast_Score=298, Evalue=7e-82,
Organism=Escherichia coli, GI1790005, Length=521, Percent_Identity=28.5988483685221, Blast_Score=155, Evalue=8e-39,
Organism=Escherichia coli, GI1787789, Length=368, Percent_Identity=27.1739130434783, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1790361, Length=490, Percent_Identity=25.5102040816327, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789168, Length=427, Percent_Identity=23.6533957845433, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17535599, Length=458, Percent_Identity=25.1091703056769, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321633, Length=387, Percent_Identity=21.9638242894057, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17864214, Length=476, Percent_Identity=24.3697478991597, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24655555, Length=454, Percent_Identity=23.3480176211454, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655560, Length=454, Percent_Identity=23.3480176211454, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655570, Length=454, Percent_Identity=23.3480176211454, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655574, Length=454, Percent_Identity=23.3480176211454, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655565, Length=454, Percent_Identity=23.3480176211454, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24654573, Length=407, Percent_Identity=24.3243243243243, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19922058, Length=516, Percent_Identity=24.031007751938, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21356607, Length=554, Percent_Identity=20.3971119133574, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 53440; Mature: 53440

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWIEGARRAVAG
CCCEEEEECCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALAKAPTLELLCVGLSGQMHGLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGL
HHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHEEECCCCCCHHHHHHHHHHCCHHEE
LAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDYLRLRLTGEVATEVSDASGTG
EEECCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCC
LFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
EEEHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHH
VIQTFGSGVIAPGELQTTIGTAGILAAALDTPQANPDGRLQVFCHVVADKWHCMGVSLNA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEEEEEECC
GGAMSWFRDTFYVGVNAAVPSFDQFTPSFEQIVAEAAASPAGARGLLFLPYLNGERCPHP
CCCHHHHHCEEEEEECCCCCCCHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
DPAARGAFIGLTACHNRGDVARAVMEGVVHALVDMHTLMKPLGINGRVVKTSGGGARSPL
CCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
WRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITREPPNPAT
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCCCHH
AAVVAEAQRIYRTLYPALRETFAELGDPTFM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWIEGARRAVAG
CCCEEEEECCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALAKAPTLELLCVGLSGQMHGLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGL
HHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHEEECCCCCCHHHHHHHHHHCCHHEE
LAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDYLRLRLTGEVATEVSDASGTG
EEECCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCC
LFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
EEEHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHH
VIQTFGSGVIAPGELQTTIGTAGILAAALDTPQANPDGRLQVFCHVVADKWHCMGVSLNA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEEEEEECC
GGAMSWFRDTFYVGVNAAVPSFDQFTPSFEQIVAEAAASPAGARGLLFLPYLNGERCPHP
CCCHHHHHCEEEEEECCCCCCCHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
DPAARGAFIGLTACHNRGDVARAVMEGVVHALVDMHTLMKPLGINGRVVKTSGGGARSPL
CCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
WRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITREPPNPAT
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCCCHH
AAVVAEAQRIYRTLYPALRETFAELGDPTFM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]