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The map label for this gene is metI [H]

Identifier: 170024966

GI number: 170024966

Start: 3023950

End: 3024621

Strand: Reverse

Name: metI [H]

Synonym: YPK_2741

Alternate gene names: 170024966

Gene position: 3024621-3023950 (Counterclockwise)

Preceding gene: 170024967

Following gene: 170024965

Centisome position: 64.5

GC content: 50.74

Gene sequence:

>672_bases
ATGAAAAATGGCATGAGTTGGCAGGAATTACTGGTATTAGTCGCTAATGCCAGCGGAGAAACGATTTATATGGTGATGAT
CGCGACCTTTTTCACCGTATTGATTGGTTTGCCATTGGGGGTTTTACTGTTTGTCTCGCGACCCGCAGGAGTGCTACCAG
CACCACGGCTGAATACCTTGATTGGTGCACTGGTCAATGTGGGGCGTTCAATGCCTTTTGTGGTGTTACTCATCGCCTTA
ATCCCCATCACCCGCTGGATTATCGGTACCACACTGGGCAGTACTGCGGCCATTGTCCCTATCACGTTAGGGGCGATCCC
CTTCTTTGCGCGGGTCGTTGAGGCGGCATTGGACGAAGTCGATAAAGGGCGCGTAGAAGCTATTTTATCCATGGGTGGCT
CTGCCCGCCATGTCATCCAAAAAGTGTTGTTGCCAGAGGCGCTGCCTGCATTATTGGCAGGTATAACATTAACGGTAGTG
ATGCTGGTGGGATTCTCATCCATGGCTGGCGTGATCGGTGGTGGTGGGTTGGGTGATTTAGCCATTCGCTACGGCTATCA
GCGCTTTAATAATGAAGTGATGGTCGCAACATTAGTGATACTGGTGATTTTAGTTCAAGGGATACAAAGCCTTGGCGATA
GGTGGGTTAGGTCACTGGCACACCGCCGCTGA

Upstream 100 bases:

>100_bases
TTGGGCGCTTGCACGTTGATTTCAACCGTCCAGAGGGCGGGTTGAATTTAGCCGAAGTGTTACAGTTTTTGAATGATCGC
GGTGTGAGGGCCGAGCTGAT

Downstream 100 bases:

>100_bases
TACCATTCACGCTATATTTTTCACTCTTTGCCCTATATTCTCCGTTCGTTATCTCATACCTCTCTTTAGTGCTTAGATTG
CCGGGCGCTTAGCCAAGGAG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKNGMSWQELLVLVANASGETIYMVMIATFFTVLIGLPLGVLLFVSRPAGVLPAPRLNTLIGALVNVGRSMPFVVLLIAL
IPITRWIIGTTLGSTAAIVPITLGAIPFFARVVEAALDEVDKGRVEAILSMGGSARHVIQKVLLPEALPALLAGITLTVV
MLVGFSSMAGVIGGGGLGDLAIRYGYQRFNNEVMVATLVILVILVQGIQSLGDRWVRSLAHRR

Sequences:

>Translated_223_residues
MKNGMSWQELLVLVANASGETIYMVMIATFFTVLIGLPLGVLLFVSRPAGVLPAPRLNTLIGALVNVGRSMPFVVLLIAL
IPITRWIIGTTLGSTAAIVPITLGAIPFFARVVEAALDEVDKGRVEAILSMGGSARHVIQKVLLPEALPALLAGITLTVV
MLVGFSSMAGVIGGGGLGDLAIRYGYQRFNNEVMVATLVILVILVQGIQSLGDRWVRSLAHRR
>Mature_223_residues
MKNGMSWQELLVLVANASGETIYMVMIATFFTVLIGLPLGVLLFVSRPAGVLPAPRLNTLIGALVNVGRSMPFVVLLIAL
IPITRWIIGTTLGSTAAIVPITLGAIPFFARVVEAALDEVDKGRVEAILSMGGSARHVIQKVLLPEALPALLAGITLTVV
MLVGFSSMAGVIGGGGLGDLAIRYGYQRFNNEVMVATLVILVILVQGIQSLGDRWVRSLAHRR

Specific function: Part of the binding-protein-dependent transport system for D-methionine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=222, Percent_Identity=46.3963963963964, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789033, Length=197, Percent_Identity=28.4263959390863, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23652; Mature: 23652

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNGMSWQELLVLVANASGETIYMVMIATFFTVLIGLPLGVLLFVSRPAGVLPAPRLNTL
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
IGALVNVGRSMPFVVLLIALIPITRWIIGTTLGSTAAIVPITLGAIPFFARVVEAALDEV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DKGRVEAILSMGGSARHVIQKVLLPEALPALLAGITLTVVMLVGFSSMAGVIGGGGLGDL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AIRYGYQRFNNEVMVATLVILVILVQGIQSLGDRWVRSLAHRR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNGMSWQELLVLVANASGETIYMVMIATFFTVLIGLPLGVLLFVSRPAGVLPAPRLNTL
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
IGALVNVGRSMPFVVLLIALIPITRWIIGTTLGSTAAIVPITLGAIPFFARVVEAALDEV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DKGRVEAILSMGGSARHVIQKVLLPEALPALLAGITLTVVMLVGFSSMAGVIGGGGLGDL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AIRYGYQRFNNEVMVATLVILVILVQGIQSLGDRWVRSLAHRR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]