Click here to switch to the map view.

The map label for this gene is kdsB [H]

Identifier: 170024885

GI number: 170024885

Start: 2926741

End: 2927493

Strand: Reverse

Name: kdsB [H]

Synonym: YPK_2660

Alternate gene names: 170024885

Gene position: 2927493-2926741 (Counterclockwise)

Preceding gene: 170024886

Following gene: 170024884

Centisome position: 62.43

GC content: 51.26

Gene sequence:

>753_bases
ATGAGTTTCATTGCTATAATTCCCGCCCGCTATGCTTCAACCCGTTTACCCGGCAAACCACTGGCTGATATTGCGGGCAA
ACCGATGGTCGTCCATGTTATGGAGCGGGCCTTGGCGTCAGGTGCTGACCGGGTGATTGTGGCAACAGACCATCCAGATG
TGGTCAAGGCGGTTGAGGCCGCAGGTGGTGAAGTGTGCCTGACCCGTGCTGATCATCAGTCTGGCACTGAACGGTTAGCC
GAAGTTATTGAACACTATGGTTTTGCTGATGACGATATTATCGTCAATGTTCAGGGCGATGAACCCCTGGTGCCGCCGGT
GATTATCCGTCAGGTTGCTGATAATTTGGCTGCATGTAGTGCCGGCATGGCGACGTTGGCTGTTCCCATTGCAAGCAGTG
AAGAGGCGTTTAACCCTAATGCCGTTAAAGTGGTTATGGATGCTCAGGGTTATGCCCTCTACTTTTCCAGGGCCACCATT
CCGTGGGAAAGAGAGCGCTTTGCTCAATCAAAAGAGACTATCGGTGATTGTTTCTTACGTCACATCGGTATCTATGCCTA
TCGAGCAGGTTTTATCCGTCGCTATGTTAACTGGGCACCCAGTCAGCTTGAGCAAATTGAATTGTTAGAGCAACTGCGGG
TGTTATGGTACGGCGAGAAAATTCACGTTGCGGTGGCGAAAGCTGTGCCTGCGGTTGGGGTTGATACGCAGAGCGATTTA
GACCGAGTCCGGGCTATCATGCTCAATCAATAA

Upstream 100 bases:

>100_bases
TGGTGTGTAAGGTGGATAATCTGGCTTACCCGGTACGCGACGGTATCCCTGTCTTGTTGGAAAACGAGGCCCGTCCACTG
TCAATTGATGAGAAGCACGC

Downstream 100 bases:

>100_bases
ATTGCGCGACGGAAACTTTACGCCAGAACCTACCGGGCTCTGGCGTTGTTATTTCTAACCTCGGTTTATTGCTTTTCGCT
TTATTTACTGCCTTCTCTTT

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGTERLA
EVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATI
PWERERFAQSKETIGDCFLRHIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDL
DRVRAIMLNQ

Sequences:

>Translated_250_residues
MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGTERLA
EVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATI
PWERERFAQSKETIGDCFLRHIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDL
DRVRAIMLNQ
>Mature_249_residues
SFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGTERLAE
VIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATIP
WERERFAQSKETIGDCFLRHIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDLD
RVRAIMLNQ

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=247, Percent_Identity=77.7327935222672, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27337; Mature: 27205

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEA
CCEEEEECCHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
AGGEVCLTRADHQSGTERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACS
CCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
AGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATIPWERERFAQSKETIGDCFLR
CCHHHEEEECCCCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
HIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCHHHH
DRVRAIMLNQ
HHHHHHHCCC
>Mature Secondary Structure 
SFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEA
CEEEEECCHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
AGGEVCLTRADHQSGTERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACS
CCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
AGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATIPWERERFAQSKETIGDCFLR
CCHHHEEEECCCCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
HIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCHHHH
DRVRAIMLNQ
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA