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The map label for this gene is uup [H]

Identifier: 170024865

GI number: 170024865

Start: 2896731

End: 2898644

Strand: Reverse

Name: uup [H]

Synonym: YPK_2640

Alternate gene names: 170024865

Gene position: 2898644-2896731 (Counterclockwise)

Preceding gene: 170024866

Following gene: 170024864

Centisome position: 61.81

GC content: 49.11

Gene sequence:

>1914_bases
ATGTCGTTAATTAGCATGTCTGGAGCCTGGCTGTCGTTCAGCGATGCACCTTTATTAGATAACACTGAATTACATATCGA
GGCGAACGAGCGTGTTTGTCTGGTGGGCCGCAACGGTGCGGGCAAATCCACCTTGCTTAAAATTCTAAGTAAAGAAGTTG
CATTAGATGATGGCCGAATCATTTATGAACAGGATCTGATTGTGGCGCGTCTGCAACAAGATCCGCCGCGTAATGTGGCC
GGTACCGTGTTTGATTTTGTGGCTGAAGGGGTGCAGGAACAGGCTGAACATCTAAAAGCCTATCACGCAACGCTGCATCA
GGTAGAACTGGATCCGAGTGAAAAAAATCTCAATCGCTTAGCGGCATTGCAAGAAATTCTGGATCACCAAGGGTTGTGGC
AACTGGATAGCCGTATTCAAGAAGTGCTGGTTCAACTGGGGTTATCCGCTGATGCTGAACTTTCTTCACTGTCGGGCGGT
TGGTTGCGCAAAGCGGCACTAGGCCGTGCATTGGTAAGCTCACCAAAAGTGTTATTACTGGATGAACCAACCAACCACCT
GGATATCGAAACCATCAACTGGCTGGAAGGCTTCCTGAAAGAGTTCCAGGGCAGCATTGTATTTATCTCCCATGACCGCT
CCTTTATTCGTGCAATGGCGACCCGTATTGTGGATTTGGATCGCGGTAAATTGGTTTCATGGCCGGGTAACTATGAGCTG
TATCTTGCCAGCAAAGAAGAAGCCTTGCGGATTGAAGAGCTGCAAAACGCTGAATTTGACCGCAAACTGGCCCAAGAAGA
AGTCTGGATACGCCAGGGCATCAAAGCGCGCCGTACCCGTAACGAAGGCCGCGTTCGTGCGCTGAAAGCGTTACGGATGG
AACGTTCGCAGCGCCGTGAGGTGATGGGCACCGCCAAGATGCAAGTGGAAGAGACGGTACGTTCTGGCAAAATTGTCTTC
GATCTGGAAAATGTTAATTATCAGATTGATGGTAAAGTGCTGGTGAAAGATTTCACCGCTCAAGTACAGCGTGGTGACAA
AATTGCGTTGGTGGGGCCAAATGGCTGCGGTAAGACGACCTTACTGAAACTGATGCTCGGTCAGCTTAACGCGGACAGCG
GTAAAGTGCATTGCGGGACCAAGCTGGAAGTCGCCTATTTTGACCAGCATCGTGCGGAGCTGGATCCCGAGCGCACGGTT
ATGGATAACCTGGCGGAAGGTAAACAAGAAGTGATGGTAAATGGCCGCTCACGCCATGTACTGGGCTATCTGCAAGACTT
CCTATTCCACCCTAAACGCGCGATGACACCGGTGAAAGCTTTGTCTGGTGGCGAGCGCAACCGTCTGTTATTGGCCAAAT
TATTCCTTAAGCCAAGTAACTTGCTGATCCTCGATGAACCAACCAATGACTTGGATGTTGAGACACTGGAATTGCTGGAA
GAGATGGTCGATAGCTATCAGGGCACCGTACTGTTGGTTAGTCATGACCGTCAATTCGTTGATAACTCAGTGACTGAATG
TTGGATCTTTGAAGGCAATGGTCAAATCAACAGCTTCGTTGGCGGCTATTATGATGCGCATCAACAACGGGCAGAGGCCA
AGCCGATTCGTCAGGCCGCACTTAAGATTGAAGAAACCAAAGCGTCTACTTCGGTTAAAAGCCCTGCACCCGCGGCTAAA
AAACCCGGTAAATTGAGCTATAACTTACAACGTGAGTTGGATCAGTTGCCGCAACAGCTAGAAAAATTGGAAAATGATAT
CAGCAAGTTACAGGCTGAAGTCAGTGATACTGATTTCTTTTCCCGCCCACACGAAGAGACTCAACAGGTTTTGAAAACCC
TGGCTGATACTGAGCAGGCGTTAGAGGTGGCATTCAGTCGTTGGGAAGAGCTGGAAGCTCAGAAAAACGGCTAA

Upstream 100 bases:

>100_bases
AAGAGATAACCGCACTTACACAATCTGAAGACTTTGCCCGTAATCGTCAGATCCACAATTGTTGGCTGGTCACCCACAGC
CAAGAGGAAAAGTAAAAACT

Downstream 100 bases:

>100_bases
AAATGCGTTACACCGTTCTGCCAGGTGACGTAATGTTGTGCTTTGTGATGATATTGTGTTTATTGTTACATTGAGTCTCT
TGATAGAACGGTGTTCAGCT

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSLISMSGAWLSFSDAPLLDNTELHIEANERVCLVGRNGAGKSTLLKILSKEVALDDGRIIYEQDLIVARLQQDPPRNVA
GTVFDFVAEGVQEQAEHLKAYHATLHQVELDPSEKNLNRLAALQEILDHQGLWQLDSRIQEVLVQLGLSADAELSSLSGG
WLRKAALGRALVSSPKVLLLDEPTNHLDIETINWLEGFLKEFQGSIVFISHDRSFIRAMATRIVDLDRGKLVSWPGNYEL
YLASKEEALRIEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKALRMERSQRREVMGTAKMQVEETVRSGKIVF
DLENVNYQIDGKVLVKDFTAQVQRGDKIALVGPNGCGKTTLLKLMLGQLNADSGKVHCGTKLEVAYFDQHRAELDPERTV
MDNLAEGKQEVMVNGRSRHVLGYLQDFLFHPKRAMTPVKALSGGERNRLLLAKLFLKPSNLLILDEPTNDLDVETLELLE
EMVDSYQGTVLLVSHDRQFVDNSVTECWIFEGNGQINSFVGGYYDAHQQRAEAKPIRQAALKIEETKASTSVKSPAPAAK
KPGKLSYNLQRELDQLPQQLEKLENDISKLQAEVSDTDFFSRPHEETQQVLKTLADTEQALEVAFSRWEELEAQKNG

Sequences:

>Translated_637_residues
MSLISMSGAWLSFSDAPLLDNTELHIEANERVCLVGRNGAGKSTLLKILSKEVALDDGRIIYEQDLIVARLQQDPPRNVA
GTVFDFVAEGVQEQAEHLKAYHATLHQVELDPSEKNLNRLAALQEILDHQGLWQLDSRIQEVLVQLGLSADAELSSLSGG
WLRKAALGRALVSSPKVLLLDEPTNHLDIETINWLEGFLKEFQGSIVFISHDRSFIRAMATRIVDLDRGKLVSWPGNYEL
YLASKEEALRIEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKALRMERSQRREVMGTAKMQVEETVRSGKIVF
DLENVNYQIDGKVLVKDFTAQVQRGDKIALVGPNGCGKTTLLKLMLGQLNADSGKVHCGTKLEVAYFDQHRAELDPERTV
MDNLAEGKQEVMVNGRSRHVLGYLQDFLFHPKRAMTPVKALSGGERNRLLLAKLFLKPSNLLILDEPTNDLDVETLELLE
EMVDSYQGTVLLVSHDRQFVDNSVTECWIFEGNGQINSFVGGYYDAHQQRAEAKPIRQAALKIEETKASTSVKSPAPAAK
KPGKLSYNLQRELDQLPQQLEKLENDISKLQAEVSDTDFFSRPHEETQQVLKTLADTEQALEVAFSRWEELEAQKNG
>Mature_636_residues
SLISMSGAWLSFSDAPLLDNTELHIEANERVCLVGRNGAGKSTLLKILSKEVALDDGRIIYEQDLIVARLQQDPPRNVAG
TVFDFVAEGVQEQAEHLKAYHATLHQVELDPSEKNLNRLAALQEILDHQGLWQLDSRIQEVLVQLGLSADAELSSLSGGW
LRKAALGRALVSSPKVLLLDEPTNHLDIETINWLEGFLKEFQGSIVFISHDRSFIRAMATRIVDLDRGKLVSWPGNYELY
LASKEEALRIEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKALRMERSQRREVMGTAKMQVEETVRSGKIVFD
LENVNYQIDGKVLVKDFTAQVQRGDKIALVGPNGCGKTTLLKLMLGQLNADSGKVHCGTKLEVAYFDQHRAELDPERTVM
DNLAEGKQEVMVNGRSRHVLGYLQDFLFHPKRAMTPVKALSGGERNRLLLAKLFLKPSNLLILDEPTNDLDVETLELLEE
MVDSYQGTVLLVSHDRQFVDNSVTECWIFEGNGQINSFVGGYYDAHQQRAEAKPIRQAALKIEETKASTSVKSPAPAAKK
PGKLSYNLQRELDQLPQQLEKLENDISKLQAEVSDTDFFSRPHEETQQVLKTLADTEQALEVAFSRWEELEAQKNG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=543, Percent_Identity=31.3075506445672, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI10947137, Length=518, Percent_Identity=30.3088803088803, Blast_Score=193, Evalue=5e-49,
Organism=Homo sapiens, GI27881506, Length=518, Percent_Identity=30.3088803088803, Blast_Score=193, Evalue=5e-49,
Organism=Homo sapiens, GI10947135, Length=554, Percent_Identity=28.158844765343, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI69354671, Length=554, Percent_Identity=28.3393501805054, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI42741659, Length=259, Percent_Identity=23.9382239382239, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1787182, Length=637, Percent_Identity=77.2370486656201, Blast_Score=975, Evalue=0.0,
Organism=Escherichia coli, GI2367384, Length=521, Percent_Identity=33.9731285988484, Blast_Score=295, Evalue=9e-81,
Organism=Escherichia coli, GI1787041, Length=513, Percent_Identity=32.1637426900585, Blast_Score=258, Evalue=8e-70,
Organism=Escherichia coli, GI1789751, Length=631, Percent_Identity=28.0507131537242, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1788506, Length=519, Percent_Identity=25.4335260115607, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=31.9371727748691, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787029, Length=252, Percent_Identity=28.1746031746032, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788225, Length=259, Percent_Identity=25.4826254826255, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788761, Length=226, Percent_Identity=29.2035398230088, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1786975, Length=220, Percent_Identity=30.9090909090909, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790467, Length=249, Percent_Identity=26.9076305220884, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786319, Length=225, Percent_Identity=29.3333333333333, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789891, Length=248, Percent_Identity=26.2096774193548, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081791, Length=200, Percent_Identity=30.5, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787712, Length=239, Percent_Identity=27.6150627615063, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786872, Length=211, Percent_Identity=29.8578199052133, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786398, Length=229, Percent_Identity=28.82096069869, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081834, Length=222, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787164, Length=173, Percent_Identity=32.3699421965318, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787105, Length=228, Percent_Identity=29.3859649122807, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI48994997, Length=214, Percent_Identity=25.7009345794392, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786563, Length=180, Percent_Identity=31.1111111111111, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787758, Length=168, Percent_Identity=27.9761904761905, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787370, Length=187, Percent_Identity=26.7379679144385, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1787089, Length=275, Percent_Identity=23.6363636363636, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=549, Percent_Identity=28.7795992714025, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17555318, Length=521, Percent_Identity=28.5988483685221, Blast_Score=204, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17553372, Length=549, Percent_Identity=30.4189435336976, Blast_Score=185, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI115533608, Length=211, Percent_Identity=29.8578199052133, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=236, Percent_Identity=26.271186440678, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=204, Percent_Identity=27.9411764705882, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=537, Percent_Identity=30.1675977653631, Blast_Score=207, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6320874, Length=526, Percent_Identity=29.467680608365, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6323278, Length=385, Percent_Identity=24.9350649350649, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324314, Length=387, Percent_Identity=25.0645994832041, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6325030, Length=383, Percent_Identity=26.1096605744125, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24666836, Length=542, Percent_Identity=30.2583025830258, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24641342, Length=548, Percent_Identity=29.1970802919708, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24642252, Length=533, Percent_Identity=28.8930581613508, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI18859989, Length=533, Percent_Identity=28.8930581613508, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI116007184, Length=175, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221500365, Length=175, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281363262, Length=219, Percent_Identity=25.1141552511416, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24653245, Length=219, Percent_Identity=25.1141552511416, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17136662, Length=212, Percent_Identity=25.4716981132075, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71678; Mature: 71547

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLISMSGAWLSFSDAPLLDNTELHIEANERVCLVGRNGAGKSTLLKILSKEVALDDGRI
CCEEECCCCEEECCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCE
IYEQDLIVARLQQDPPRNVAGTVFDFVAEGVQEQAEHLKAYHATLHQVELDPSEKNLNRL
EEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHH
AALQEILDHQGLWQLDSRIQEVLVQLGLSADAELSSLSGGWLRKAALGRALVSSPKVLLL
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEE
DEPTNHLDIETINWLEGFLKEFQGSIVFISHDRSFIRAMATRIVDLDRGKLVSWPGNYEL
ECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCEEE
YLASKEEALRIEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKALRMERSQRRE
EEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
VMGTAKMQVEETVRSGKIVFDLENVNYQIDGKVLVKDFTAQVQRGDKIALVGPNGCGKTT
HHHHHHHHHHHHHHCCCEEEEEECCCEEECCEEEEEHHHHHHHCCCEEEEECCCCCCHHH
LLKLMLGQLNADSGKVHCGTKLEVAYFDQHRAELDPERTVMDNLAEGKQEVMVNGRSRHV
HHHHHHHHCCCCCCEEECCCEEEEEEECCHHHCCCHHHHHHHHHHCCCHHHEECCCCHHH
LGYLQDFLFHPKRAMTPVKALSGGERNRLLLAKLFLKPSNLLILDEPTNDLDVETLELLE
HHHHHHHHHCCHHHCCHHHHHCCCCCCCEEEEHHHCCCCCEEEEECCCCCCCHHHHHHHH
EMVDSYQGTVLLVSHDRQFVDNSVTECWIFEGNGQINSFVGGYYDAHQQRAEAKPIRQAA
HHHHHHCCEEEEEECCHHHHCCCCCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHH
LKIEETKASTSVKSPAPAAKKPGKLSYNLQRELDQLPQQLEKLENDISKLQAEVSDTDFF
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SRPHEETQQVLKTLADTEQALEVAFSRWEELEAQKNG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLISMSGAWLSFSDAPLLDNTELHIEANERVCLVGRNGAGKSTLLKILSKEVALDDGRI
CEEECCCCEEECCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCE
IYEQDLIVARLQQDPPRNVAGTVFDFVAEGVQEQAEHLKAYHATLHQVELDPSEKNLNRL
EEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHH
AALQEILDHQGLWQLDSRIQEVLVQLGLSADAELSSLSGGWLRKAALGRALVSSPKVLLL
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEE
DEPTNHLDIETINWLEGFLKEFQGSIVFISHDRSFIRAMATRIVDLDRGKLVSWPGNYEL
ECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCEEE
YLASKEEALRIEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKALRMERSQRRE
EEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
VMGTAKMQVEETVRSGKIVFDLENVNYQIDGKVLVKDFTAQVQRGDKIALVGPNGCGKTT
HHHHHHHHHHHHHHCCCEEEEEECCCEEECCEEEEEHHHHHHHCCCEEEEECCCCCCHHH
LLKLMLGQLNADSGKVHCGTKLEVAYFDQHRAELDPERTVMDNLAEGKQEVMVNGRSRHV
HHHHHHHHCCCCCCEEECCCEEEEEEECCHHHCCCHHHHHHHHHHCCCHHHEECCCCHHH
LGYLQDFLFHPKRAMTPVKALSGGERNRLLLAKLFLKPSNLLILDEPTNDLDVETLELLE
HHHHHHHHHCCHHHCCHHHHHCCCCCCCEEEEHHHCCCCCEEEEECCCCCCCHHHHHHHH
EMVDSYQGTVLLVSHDRQFVDNSVTECWIFEGNGQINSFVGGYYDAHQQRAEAKPIRQAA
HHHHHHCCEEEEEECCHHHHCCCCCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHH
LKIEETKASTSVKSPAPAAKKPGKLSYNLQRELDQLPQQLEKLENDISKLQAEVSDTDFF
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SRPHEETQQVLKTLADTEQALEVAFSRWEELEAQKNG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9139905; 7751275 [H]