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The map label for this gene is yegH [H]

Identifier: 170024774

GI number: 170024774

Start: 2794610

End: 2796196

Strand: Direct

Name: yegH [H]

Synonym: YPK_2549

Alternate gene names: 170024774

Gene position: 2794610-2796196 (Clockwise)

Preceding gene: 170024768

Following gene: 170024779

Centisome position: 59.59

GC content: 46.94

Gene sequence:

>1587_bases
ATGGAATGGATCGCGGATCCAACTATTTGGGCAGGACTGGCTACATTGGTTGTGCTCGAAATTGTATTGGGTATTGATAA
CCTTATATTTATTGCCATCTTGGCAGAGAAACTTCCTCGTCATCAACGAGACAAAGCCAGAGTCACTGGTTTACTCTGCG
CATTGTTAATGCGTCTGGCACTGTTGGCCTGTATTTCGTGGCTGGCTACATTGACCACACCAATAGTCACTCTCTCTGAA
CATTCGTTCAGTGCACGTGACTTGATTATGTTGGTCGGGGGAATATTCCTGCTGTTCAAAGCTACGATGGAGCTAAATGA
ACGGCTGGAAGGGAAAGATCATCAGCAGAATCAGCAACGCAAAGCGGCTCGTTTCTGGCCGGTGGTGGCACAGATAGTGG
TTCTGGATGCTATCTTCTCGCTCGATTCCGTGATCACCGCCGTCGGCATGGTTGATCACCTTGCGGTGATGATGGTCGCC
GTTTGTATCGCAATTGGCTTGATGTTACTCGCCAGTAAACCGTTGACTCGCTTTGTCAATGCACATCCAACGATTGTCAT
TCTGTGCTTGAGCTTCTTACTGATGATCGGTTTCAGCTTAGTCGCTGAAGGTTTTGGTTACCATATTCCTAAGGGCTACC
TGTACGCGGCTATTGGTTTCTCAGTAATTATTGAGTCACTGAACCAGTTTGCACAATTCAATCGTCGGCGCTTCCTGTCA
ACGGTTAGACCATTACGCGAACGTACCGCAGAGGCCGTTTTACGGATGCTCAGTGGCAAACACGAAGAAGCTGAATTGGA
TAACCATACTGCCAATCTGATCGCTGATAATACCAGCGAAGGCCAGGAAGTGTTCAATGCGCAAGAACGGCGCATGATTG
AACGGGTCTTAGGGCTGGCACAGCGAACCGTCAGTAGCATCATGACATCACGCCATGATGTTGAATATTTGGACCTCAAT
GACCCACCAGAGAAATTGACTCAGTTGCTGGCGAAAAATCTGCATACCCGGATCGTGGTTACTGAAGATAGCTCTACTGA
TGAACCTTTGGGAGTTATTCACGTAATTGATTTATTGAAACAACAATTAGCGAATGAAAAACTCGACTTGCGGTCATTAA
TTCGCCAACCACTTATCTTTCCTGAGCAAGTTTCATTGCTGATGGCTCTGGAACAATTCCGTCAGGCACAGACACATTTT
GCTTTTGTCGTCGATGAGTTCGGTTCTATTGAGGGGGTTGTGACCCTTACCGACGTGATGGAAACTATCGCAGGTAACTT
ACCCGTAGCAGGGGAAGAGTTAGATGCGCGCCACGATATTCAGCAAACTGAAGATGGCTGTTGGATAGCGAACGGTTATA
TGCCGCTGGAAGATTTGGTGCTCTATTTGCCGCTGCCAATTGATGAAAAACGTGAATACCACACACTGGCCGGGTTACTC
ATGGAGCATACCCAGAGGATACCCAAAGTAGGTGAACAACTGACCATTGGCGATTACTTATTCGAACCTCTGGTGGTCAA
TAGCCACAGGATCTTAAAAGTGAAGATAACACCATTGAAGATTCCTGAGCCAGATTACGAAGTGTAG

Upstream 100 bases:

>100_bases
ATTTTTTTGTGATCGACTCTGGTCGATGCACTTCTTTAACAAATGGCTATTTTTCTGATTGACGGCATAAGCCGTAGCAA
TACAAGGTGAAACTGGATAT

Downstream 100 bases:

>100_bases
TTAATTGATAACGCTATAGATTAGGTGAATTAACAAAAGCCTGGAAAAATAAATGATTAGGCCCGGTGGAGAAACCATCG
GGCCTATCTCTTTCCACTAC

Product: integral membrane protein TerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MEWIADPTIWAGLATLVVLEIVLGIDNLIFIAILAEKLPRHQRDKARVTGLLCALLMRLALLACISWLATLTTPIVTLSE
HSFSARDLIMLVGGIFLLFKATMELNERLEGKDHQQNQQRKAARFWPVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMVA
VCIAIGLMLLASKPLTRFVNAHPTIVILCLSFLLMIGFSLVAEGFGYHIPKGYLYAAIGFSVIIESLNQFAQFNRRRFLS
TVRPLRERTAEAVLRMLSGKHEEAELDNHTANLIADNTSEGQEVFNAQERRMIERVLGLAQRTVSSIMTSRHDVEYLDLN
DPPEKLTQLLAKNLHTRIVVTEDSSTDEPLGVIHVIDLLKQQLANEKLDLRSLIRQPLIFPEQVSLLMALEQFRQAQTHF
AFVVDEFGSIEGVVTLTDVMETIAGNLPVAGEELDARHDIQQTEDGCWIANGYMPLEDLVLYLPLPIDEKREYHTLAGLL
MEHTQRIPKVGEQLTIGDYLFEPLVVNSHRILKVKITPLKIPEPDYEV

Sequences:

>Translated_528_residues
MEWIADPTIWAGLATLVVLEIVLGIDNLIFIAILAEKLPRHQRDKARVTGLLCALLMRLALLACISWLATLTTPIVTLSE
HSFSARDLIMLVGGIFLLFKATMELNERLEGKDHQQNQQRKAARFWPVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMVA
VCIAIGLMLLASKPLTRFVNAHPTIVILCLSFLLMIGFSLVAEGFGYHIPKGYLYAAIGFSVIIESLNQFAQFNRRRFLS
TVRPLRERTAEAVLRMLSGKHEEAELDNHTANLIADNTSEGQEVFNAQERRMIERVLGLAQRTVSSIMTSRHDVEYLDLN
DPPEKLTQLLAKNLHTRIVVTEDSSTDEPLGVIHVIDLLKQQLANEKLDLRSLIRQPLIFPEQVSLLMALEQFRQAQTHF
AFVVDEFGSIEGVVTLTDVMETIAGNLPVAGEELDARHDIQQTEDGCWIANGYMPLEDLVLYLPLPIDEKREYHTLAGLL
MEHTQRIPKVGEQLTIGDYLFEPLVVNSHRILKVKITPLKIPEPDYEV
>Mature_528_residues
MEWIADPTIWAGLATLVVLEIVLGIDNLIFIAILAEKLPRHQRDKARVTGLLCALLMRLALLACISWLATLTTPIVTLSE
HSFSARDLIMLVGGIFLLFKATMELNERLEGKDHQQNQQRKAARFWPVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMVA
VCIAIGLMLLASKPLTRFVNAHPTIVILCLSFLLMIGFSLVAEGFGYHIPKGYLYAAIGFSVIIESLNQFAQFNRRRFLS
TVRPLRERTAEAVLRMLSGKHEEAELDNHTANLIADNTSEGQEVFNAQERRMIERVLGLAQRTVSSIMTSRHDVEYLDLN
DPPEKLTQLLAKNLHTRIVVTEDSSTDEPLGVIHVIDLLKQQLANEKLDLRSLIRQPLIFPEQVSLLMALEQFRQAQTHF
AFVVDEFGSIEGVVTLTDVMETIAGNLPVAGEELDARHDIQQTEDGCWIANGYMPLEDLVLYLPLPIDEKREYHTLAGLL
MEHTQRIPKVGEQLTIGDYLFEPLVVNSHRILKVKITPLKIPEPDYEV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=258, Percent_Identity=23.2558139534884, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI87082033, Length=529, Percent_Identity=72.0226843100189, Blast_Score=752, Evalue=0.0,
Organism=Escherichia coli, GI1788119, Length=517, Percent_Identity=49.5164410058027, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI1789197, Length=226, Percent_Identity=50.8849557522124, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1790664, Length=239, Percent_Identity=33.0543933054393, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786879, Length=248, Percent_Identity=27.8225806451613, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI145693175, Length=251, Percent_Identity=26.6932270916335, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 59268; Mature: 59268

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCCHHHHHHCCCEECCCEEEEEEEEEEECCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCCHHHHHHCCCEECCCEEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]