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The map label for this gene is yeeO [H]

Identifier: 170024729

GI number: 170024729

Start: 2738369

End: 2739793

Strand: Reverse

Name: yeeO [H]

Synonym: YPK_2504

Alternate gene names: 170024729

Gene position: 2739793-2738369 (Counterclockwise)

Preceding gene: 170024731

Following gene: 170024726

Centisome position: 58.42

GC content: 50.67

Gene sequence:

>1425_bases
ATGAACAGGGTTTCAGAGGCCGTTAAGTTGAAAATCTTCCGCGAAAGCGTGTGGTATAAGAAGCGAAAATCATCTCGGGT
ACTCTTTTGGCGTGAGATCACACCGCTGGCCTTTCCGTTGTTTATTGAAGGTTTGTGCGTACTGCTGATGGGGGTATTTA
GTACTCTGCTGGTGAGTTGGTTGGGTAAAGAAGCGATGGCAGCGGTGGGGCTAGCCGACAGTTTCAATATGCTGATTGCG
GCTTTTTTTGCCTCCGTGGCATTAGGGACCTCGGTCGTTGTGGCCTTCAGTCTGGGCCAACGCAAACGCCAGCAGGCGCA
AACTGCCGCCCGACAATCCATGACATTGCTGGTATTAATCTCCCTGTTATTAGTTGTCTTGGTTCATTTTTCAGGCCAGA
CCATTATTGATTTAATGGCTAACCAGGCAGACCCCTCGGTTAAAGCAATGGCCCTGACCTATCTGCATTTCACTGTCTGG
AATTACCCTGCGATGGCGATAACCTTGGTGGGGTGCGGTGCGTTACGTGGTGCGGGCAATACGCGTTTGCCGATGCTTAT
TAACATTGGCATGAACATTCTTAACATTGTCATTAGCAGTATATTAATTTATGGCCTCTTTAATTGGCAAGGACTGGGTT
TTATCGGTGCCGGTATTGGCATCACATTGGCCCGCTCTGCAGGCGCACTGGTGGTGGTCGTGCTGCTGATTTACGGCGCG
AATAATACGTTGCGGATCCCCTTCAAAGCCTATTTCATGCCTTTTACCTCGGCCATTATGTTTGAGGTGCTGAGCATTGG
TATTCCGGCGAGTGTTGAGTCAGTTATGTTCAATATTGGCAAGTTAATCACTCAACGGTTTGTTGCCGGCATGGGGACCG
ACGTGATCGCGGGTAACTTTATTGCCTTTTCAATTGTGGCGATAATCAATCTGCCCGGTAATGCGCTGGGGTACACCTCA
ACCATTATTATTGGTACCCGGCTGGGCAAGGGGCAAATTTTGCAACCTATTCGGCAGATAAAACATATCTTTTGGCTATC
GACGCTTGGGGTCTGCTTTATTGCATTGCTGTCCATTCCCAGTGCGGGTTTTCTGGCCTCGCTGTATACCGATGATCCGG
CAGTTATCACGGTGGTGAAGCATTTGATCTGGATGAATGCGTTATTTATGCCGATTTGGGCGGCGTCTTGGGTCTTACCT
GCCGGCTTGAAAGGCGCTAAGGATGCCAGTTACACCATGTGGGTTGCCCTGGCCGGGATGTGGGGCTGTCGCATTATTGC
TGGCTACATTCTGGGGGTAACGCTAGGGTTTGGCGTGACAGGGGTATGGATGGGGATGTTCCTGGATTGGATGGTCCGGG
GGGTGTTGTTTTATCGCCGCATGTCCACGGGCCGTTGGTTATGGCGCTACCGGCCCAGCGTCTGA

Upstream 100 bases:

>100_bases
GAAACGCGCAGCGGGTTAAAATATCTAGCGGGAAATCAACATTGTAAATCGGCGCATTGGGATATTTCACCATAGTGGTG
GAAAGCGCGGATGGATGCAA

Downstream 100 bases:

>100_bases
GAATATGAGCCGGTGTCCCCCATCGAATTACTTCACACTCTGCGGTGCCACGTGGTGGGCAAACAGCATAATGACGCCAG
AGATAAAGCAGGGGATGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFIEGLCVLLMGVFSTLLVSWLGKEAMAAVGLADSFNMLIA
AFFASVALGTSVVVAFSLGQRKRQQAQTAARQSMTLLVLISLLLVVLVHFSGQTIIDLMANQADPSVKAMALTYLHFTVW
NYPAMAITLVGCGALRGAGNTRLPMLINIGMNILNIVISSILIYGLFNWQGLGFIGAGIGITLARSAGALVVVVLLIYGA
NNTLRIPFKAYFMPFTSAIMFEVLSIGIPASVESVMFNIGKLITQRFVAGMGTDVIAGNFIAFSIVAIINLPGNALGYTS
TIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLSIPSAGFLASLYTDDPAVITVVKHLIWMNALFMPIWAASWVLP
AGLKGAKDASYTMWVALAGMWGCRIIAGYILGVTLGFGVTGVWMGMFLDWMVRGVLFYRRMSTGRWLWRYRPSV

Sequences:

>Translated_474_residues
MNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFIEGLCVLLMGVFSTLLVSWLGKEAMAAVGLADSFNMLIA
AFFASVALGTSVVVAFSLGQRKRQQAQTAARQSMTLLVLISLLLVVLVHFSGQTIIDLMANQADPSVKAMALTYLHFTVW
NYPAMAITLVGCGALRGAGNTRLPMLINIGMNILNIVISSILIYGLFNWQGLGFIGAGIGITLARSAGALVVVVLLIYGA
NNTLRIPFKAYFMPFTSAIMFEVLSIGIPASVESVMFNIGKLITQRFVAGMGTDVIAGNFIAFSIVAIINLPGNALGYTS
TIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLSIPSAGFLASLYTDDPAVITVVKHLIWMNALFMPIWAASWVLP
AGLKGAKDASYTMWVALAGMWGCRIIAGYILGVTLGFGVTGVWMGMFLDWMVRGVLFYRRMSTGRWLWRYRPSV
>Mature_474_residues
MNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFIEGLCVLLMGVFSTLLVSWLGKEAMAAVGLADSFNMLIA
AFFASVALGTSVVVAFSLGQRKRQQAQTAARQSMTLLVLISLLLVVLVHFSGQTIIDLMANQADPSVKAMALTYLHFTVW
NYPAMAITLVGCGALRGAGNTRLPMLINIGMNILNIVISSILIYGLFNWQGLGFIGAGIGITLARSAGALVVVVLLIYGA
NNTLRIPFKAYFMPFTSAIMFEVLSIGIPASVESVMFNIGKLITQRFVAGMGTDVIAGNFIAFSIVAIINLPGNALGYTS
TIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLSIPSAGFLASLYTDDPAVITVVKHLIWMNALFMPIWAASWVLP
AGLKGAKDASYTMWVALAGMWGCRIIAGYILGVTLGFGVTGVWMGMFLDWMVRGVLFYRRMSTGRWLWRYRPSV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=472, Percent_Identity=63.3474576271186, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI48994890, Length=451, Percent_Identity=25.7206208425721, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51823; Mature: 51823

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFIEGLCVLLMGVFSTLLVSW
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKEAMAAVGLADSFNMLIAAFFASVALGTSVVVAFSLGQRKRQQAQTAARQSMTLLVLI
HCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLLVVLVHFSGQTIIDLMANQADPSVKAMALTYLHFTVWNYPAMAITLVGCGALRGAGN
HHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
TRLPMLINIGMNILNIVISSILIYGLFNWQGLGFIGAGIGITLARSAGALVVVVLLIYGA
CCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHEECCCCCHHHHHHHHHHCC
NNTLRIPFKAYFMPFTSAIMFEVLSIGIPASVESVMFNIGKLITQRFVAGMGTDVIAGNF
CCEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
IAFSIVAIINLPGNALGYTSTIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLSIP
HHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SAGFLASLYTDDPAVITVVKHLIWMNALFMPIWAASWVLPAGLKGAKDASYTMWVALAGM
CCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
WGCRIIAGYILGVTLGFGVTGVWMGMFLDWMVRGVLFYRRMSTGRWLWRYRPSV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MNRVSEAVKLKIFRESVWYKKRKSSRVLFWREITPLAFPLFIEGLCVLLMGVFSTLLVSW
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKEAMAAVGLADSFNMLIAAFFASVALGTSVVVAFSLGQRKRQQAQTAARQSMTLLVLI
HCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLLVVLVHFSGQTIIDLMANQADPSVKAMALTYLHFTVWNYPAMAITLVGCGALRGAGN
HHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
TRLPMLINIGMNILNIVISSILIYGLFNWQGLGFIGAGIGITLARSAGALVVVVLLIYGA
CCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHEECCCCCHHHHHHHHHHCC
NNTLRIPFKAYFMPFTSAIMFEVLSIGIPASVESVMFNIGKLITQRFVAGMGTDVIAGNF
CCEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
IAFSIVAIINLPGNALGYTSTIIIGTRLGKGQILQPIRQIKHIFWLSTLGVCFIALLSIP
HHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SAGFLASLYTDDPAVITVVKHLIWMNALFMPIWAASWVLPAGLKGAKDASYTMWVALAGM
CCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
WGCRIIAGYILGVTLGFGVTGVWMGMFLDWMVRGVLFYRRMSTGRWLWRYRPSV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]