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The map label for this gene is holE [H]

Identifier: 170024664

GI number: 170024664

Start: 2671957

End: 2672187

Strand: Direct

Name: holE [H]

Synonym: YPK_2439

Alternate gene names: 170024664

Gene position: 2671957-2672187 (Clockwise)

Preceding gene: 170024659

Following gene: 170024666

Centisome position: 56.98

GC content: 44.16

Gene sequence:

>231_bases
ATGGGATATAATTTGGTAGAGCTTTCTGACGAAGAGACGGCAAAAATGAACGTTGACCTTGCCGCCTCAGGTGTTGCATT
TAAAGAGCGCTACAATATGCCCGTTATCCCTGAAATGGTCGCCAGAGAACAACCCGAAGCTCTACGCGAGTATTTTTTAC
AACGGCTGGCACATTACCGTATCGAGTCAAAAAAATTATCTCGACTGCCGTATGAACCTAAAGTGAAGTAA

Upstream 100 bases:

>100_bases
ACTGATTCCCTATAGTTGGCAACATTACTGACTTGCCAATATCTACCGTCTGCATTACCTTTTGCGCTATCAACGCCGAT
GGTCTAAGAAGGAGAAAGAA

Downstream 100 bases:

>100_bases
TCGTGAAATGCTCCCGTAGGCCTTAACCCGCGGGAGTCAGTCGCCTTAAATGCGTAGAGTCAGTGAGCAAATTTATCAGT
AGCTAGAATAAGTTGATGCA

Product: DNA polymerase III subunit theta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 76; Mature: 75

Protein sequence:

>76_residues
MGYNLVELSDEETAKMNVDLAASGVAFKERYNMPVIPEMVAREQPEALREYFLQRLAHYRIESKKLSRLPYEPKVK

Sequences:

>Translated_76_residues
MGYNLVELSDEETAKMNVDLAASGVAFKERYNMPVIPEMVAREQPEALREYFLQRLAHYRIESKKLSRLPYEPKVK
>Mature_75_residues
GYNLVELSDEETAKMNVDLAASGVAFKERYNMPVIPEMVAREQPEALREYFLQRLAHYRIESKKLSRLPYEPKVK

Specific function: The exact function of the theta subunit is unknown [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788147, Length=76, Percent_Identity=64.4736842105263, Blast_Score=97, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009052
- InterPro:   IPR011325
- ProDom:   PD057609 [H]

Pfam domain/function: PF06440 DNA_pol3_theta [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 8889; Mature: 8758

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYNLVELSDEETAKMNVDLAASGVAFKERYNMPVIPEMVAREQPEALREYFLQRLAHYR
CCCCCCCCCCCCCCEECCCCCCCCCHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
IESKKLSRLPYEPKVK
HCCHHHHCCCCCCCCC
>Mature Secondary Structure 
GYNLVELSDEETAKMNVDLAASGVAFKERYNMPVIPEMVAREQPEALREYFLQRLAHYR
CCCCCCCCCCCCCEECCCCCCCCCHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
IESKKLSRLPYEPKVK
HCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]