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The map label for this gene is flgM [H]

Identifier: 170024652

GI number: 170024652

Start: 2658951

End: 2659253

Strand: Direct

Name: flgM [H]

Synonym: YPK_2427

Alternate gene names: 170024652

Gene position: 2658951-2659253 (Clockwise)

Preceding gene: 170024651

Following gene: 170024653

Centisome position: 56.7

GC content: 47.52

Gene sequence:

>303_bases
ATGAGCAGTATTGATCGCACTCAACCGCTATCGCCAGTAACACAAGTTCAAGCACGGGAAAGCCATGACGTAGCACAACA
AACGCGTCAGTCAGCTACCCAGACAAAAACCCCGGTCAGTGGTACTGAGGTTAAATTGAGTGATGCGCAGGCAAAATTGA
TGCAACCGGGCAGTCAGGACATCAATGTGGAGCGTGTCGAAACATTAAAACAGGCTATCCGCAGCGGTCAATTGACTATG
GATACCGGTAAAATAGCCGATGCCCTGTTAAAAAACGTGGCGGATGAGCTTAAGAATCATTAA

Upstream 100 bases:

>100_bases
GCAGGTTAATGAATAAGTGACCATCCCGCCATTCTTTTGCAAATAGACACATGTTTTGCGGGTTGATAAACGAAAATCCC
GCGATAAGGGGAGCAACACC

Downstream 100 bases:

>100_bases
TCGTAATAAGGATACGTGGTGGTGGAAAGTTTACAAACCAATCTGGACCAGCAGTTGGATCTGCTCGAATCGCTGACGAA
TGTCGTAGCACAAGAGCAAC

Product: anti-sigma-28 factor FlgM

Products: NA

Alternate protein names: Anti-sigma-28 factor [H]

Number of amino acids: Translated: 100; Mature: 99

Protein sequence:

>100_residues
MSSIDRTQPLSPVTQVQARESHDVAQQTRQSATQTKTPVSGTEVKLSDAQAKLMQPGSQDINVERVETLKQAIRSGQLTM
DTGKIADALLKNVADELKNH

Sequences:

>Translated_100_residues
MSSIDRTQPLSPVTQVQARESHDVAQQTRQSATQTKTPVSGTEVKLSDAQAKLMQPGSQDINVERVETLKQAIRSGQLTM
DTGKIADALLKNVADELKNH
>Mature_99_residues
SSIDRTQPLSPVTQVQARESHDVAQQTRQSATQTKTPVSGTEVKLSDAQAKLMQPGSQDINVERVETLKQAIRSGQLTMD
TGKIADALLKNVADELKNH

Specific function: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of

COG id: COG2747

COG function: function code KNU; Negative regulator of flagellin synthesis (anti-sigma28 factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flgM family [H]

Homologues:

Organism=Escherichia coli, GI1787311, Length=98, Percent_Identity=57.1428571428571, Blast_Score=97, Evalue=2e-22,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007412 [H]

Pfam domain/function: PF04316 FlgM [H]

EC number: NA

Molecular weight: Translated: 10897; Mature: 10766

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIDRTQPLSPVTQVQARESHDVAQQTRQSATQTKTPVSGTEVKLSDAQAKLMQPGSQD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHCCCCCC
INVERVETLKQAIRSGQLTMDTGKIADALLKNVADELKNH
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSIDRTQPLSPVTQVQARESHDVAQQTRQSATQTKTPVSGTEVKLSDAQAKLMQPGSQD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHCCCCCC
INVERVETLKQAIRSGQLTMDTGKIADALLKNVADELKNH
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8830263 [H]