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The map label for this gene is ruvA [H]

Identifier: 170024378

GI number: 170024378

Start: 2375285

End: 2375899

Strand: Reverse

Name: ruvA [H]

Synonym: YPK_2144

Alternate gene names: 170024378

Gene position: 2375899-2375285 (Counterclockwise)

Preceding gene: 170024379

Following gene: 170024377

Centisome position: 50.66

GC content: 50.24

Gene sequence:

>615_bases
GTGATAGGCCGTCTCAGAGGTATCATTCTGGAAAAACAGCCACCGCTGGTGCTGCTGGAAACAAACGGTGTTGGCTATGA
AGTCCAATTACCAATGACCTGCTTCTATGAGTTACCCGAGTTGGGGCAGGAAGCCATTATCTTCACCCAGTTTGTGGTAC
GCGAAGATGCGCAGTTACTGTATGGCTTCAATAATAAGCAGGAGCGGGCGCTGTTCCGTGAATTGATCAAAGTTAACGGC
GTCGGGCCAAAACTGGCTTTAGCCATTCTCTCCGGGATGTCTGCACAGCAATTTGTTGGCGCAGTCGAACGTGAAGATAT
TACAACGCTGGTAAAACTGCCGGGTGTCGGTAAAAAGACCGCCGAGCGGTTAGTGGTCGAAATGAAAGATCGCTTTAAAG
GCCTTAACGGCGATCTGTTTAATAATACCGGTGATATCTCGTTACCAACGGCTTCGCCACAAACCTCGGATGCTGATATC
GAAGCGGAAGCCGCTTCTGCACTGGTCGCGCTGGGTTATAAACCACAAGAGGCCAGCCGTTTAGTGAGTAAAATTGCCAA
GCCGGGTGCCGATTGTGAAACACTGATCCGTGATGCTCTCCGTGCGGCGTTATAA

Upstream 100 bases:

>100_bases
TTAAGGTCAAACGACCAGTAAGTGATTCGGGTGAATGAATGCCGCTAACCACGCAGTAGCGTCAATTCTGAAGGGGATTG
TGGGCAAGGAGAGAATCAAC

Downstream 100 bases:

>100_bases
TGCCGCCGATTTATAGAATGAATTGTGTTATATACCCAACGTTATTGACGCTGCAGATAGCTGGCAAACGAATCCCGATG
AATTTAAAAAAATTAGTCAT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MIGRLRGIILEKQPPLVLLETNGVGYEVQLPMTCFYELPELGQEAIIFTQFVVREDAQLLYGFNNKQERALFRELIKVNG
VGPKLALAILSGMSAQQFVGAVEREDITTLVKLPGVGKKTAERLVVEMKDRFKGLNGDLFNNTGDISLPTASPQTSDADI
EAEAASALVALGYKPQEASRLVSKIAKPGADCETLIRDALRAAL

Sequences:

>Translated_204_residues
MIGRLRGIILEKQPPLVLLETNGVGYEVQLPMTCFYELPELGQEAIIFTQFVVREDAQLLYGFNNKQERALFRELIKVNG
VGPKLALAILSGMSAQQFVGAVEREDITTLVKLPGVGKKTAERLVVEMKDRFKGLNGDLFNNTGDISLPTASPQTSDADI
EAEAASALVALGYKPQEASRLVSKIAKPGADCETLIRDALRAAL
>Mature_204_residues
MIGRLRGIILEKQPPLVLLETNGVGYEVQLPMTCFYELPELGQEAIIFTQFVVREDAQLLYGFNNKQERALFRELIKVNG
VGPKLALAILSGMSAQQFVGAVEREDITTLVKLPGVGKKTAERLVVEMKDRFKGLNGDLFNNTGDISLPTASPQTSDADI
EAEAASALVALGYKPQEASRLVSKIAKPGADCETLIRDALRAAL

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=79.5121951219512, Blast_Score=328, Evalue=1e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22188; Mature: 22188

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGIILEKQPPLVLLETNGVGYEVQLPMTCFYELPELGQEAIIFTQFVVREDAQLL
CCCCCCEEEEECCCCEEEEECCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCEE
YGFNNKQERALFRELIKVNGVGPKLALAILSGMSAQQFVGAVEREDITTLVKLPGVGKKT
ECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCHHH
AERLVVEMKDRFKGLNGDLFNNTGDISLPTASPQTSDADIEAEAASALVALGYKPQEASR
HHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHH
LVSKIAKPGADCETLIRDALRAAL
HHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRLRGIILEKQPPLVLLETNGVGYEVQLPMTCFYELPELGQEAIIFTQFVVREDAQLL
CCCCCCEEEEECCCCEEEEECCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCEE
YGFNNKQERALFRELIKVNGVGPKLALAILSGMSAQQFVGAVEREDITTLVKLPGVGKKT
ECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCHHH
AERLVVEMKDRFKGLNGDLFNNTGDISLPTASPQTSDADIEAEAASALVALGYKPQEASR
HHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHH
LVSKIAKPGADCETLIRDALRAAL
HHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA