Click here to switch to the map view.

The map label for this gene is rnd [H]

Identifier: 170024358

GI number: 170024358

Start: 2353998

End: 2355119

Strand: Reverse

Name: rnd [H]

Synonym: YPK_2124

Alternate gene names: 170024358

Gene position: 2355119-2353998 (Counterclockwise)

Preceding gene: 170024359

Following gene: 170024354

Centisome position: 50.22

GC content: 48.13

Gene sequence:

>1122_bases
TTGAATTATCAGTTGATCACGACCAATAACGCATTGCAACAGGTCTGCGAACAAGCCCGGACACATGCTCACATCGCGTT
GGATACAGAGTTTGTCAGAACGCGCACTTACTACCCTCAGTTGGGTTTGATTCAACTGTATGATGGTGAACAACTCTCAC
TTATAGATCCATTACCTATCACGGAATGGCAGCCTTTTCGCGCGTTACTGCAAGATCTGAATGTGGTGAAATATTTACAC
GCAGGCAGTGAAGATCTCGAAGTGTTTTTAAACGCTTTTGACCAGATGCCAACCCCGATGATTGATACTCAGGTATTAGC
GGCATTTTCTGGCCGTAGCCTATCCTGCGGCTTTGCCATGCTGGTGGCTGAGTTTGAAGGTGTTGAGTTAGATAAAAGTG
AATCACGTACAGACTGGATTGCCCGGCCGTTGAGTGAAAAACAGTGCGATTATGCGGCGGCTGATGTGTTTTATCTTTTA
CCTCTGGCGGCTAAATTAGTCGAAGCCACTGAGGCGGCAGGGCGGATGGACGCGGCGAAAGACGAATGTCTATTGCTGTG
CCGCCGTCGGAGTGAGACGCTCGATCCTGAACTGGCTTACCGTGAGATTACCAATGCCTGGCAACTCCGTGGCCATCAAC
TGGCATGTTTGCAGAAATTAGCCGAATGGCGTTTACGTCAGGCACGGGAGCGGGATTTGGCGGTTAACTTTGTGGTTAGG
GAAGAGCACCTGTGGCAAGTTGCCCGCTATCAACCAACATCACTCGGTGAGTTAGATTCTCTTGGCTTGAGTGGGCAGGA
GATCCGCTATCACGGGCGAACATTGCTGGCACTGGTCGCCGAAGGGAATGCCGTCCCTGAAGATCAGCTTCCTCCCCCGA
TTGCTAACTTGATTGACCAACCGGGGTACAAAAAAGTCTTTAAAGATATTAAAGCCTTGATTCAATCGGTCAGTGAACGT
AGCGGATTAAGCAGTGAATTACTGGCATCACGTCGCCAAATTAATCAGTTACTCAATTGGCACTGGAAGTTGAAGCTTTC
AGATGCTCAACCTGAATTATTAACAGGCTGGCGTGGCGATTTATTGTCTTCTGAATTGCTTGAAATCTTACAACACTATT
AA

Upstream 100 bases:

>100_bases
TATCGAACTATAGCCAATAGATTTTAAGAAACAGGAAGGCGGTAGCTAATAGACCTGCCACTTGAAAGATAACGGATATA
ACGACCAAGAGAATGACGTT

Downstream 100 bases:

>100_bases
TCAGTTTTGATATTAATCAGCCTTCAGGGTGGGATATTAATTCCACGCTGAAACTTTTCAGTTTTAATTTATGAACACTC
TTTTTAATTTATAAACAATC

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MNYQLITTNNALQQVCEQARTHAHIALDTEFVRTRTYYPQLGLIQLYDGEQLSLIDPLPITEWQPFRALLQDLNVVKYLH
AGSEDLEVFLNAFDQMPTPMIDTQVLAAFSGRSLSCGFAMLVAEFEGVELDKSESRTDWIARPLSEKQCDYAAADVFYLL
PLAAKLVEATEAAGRMDAAKDECLLLCRRRSETLDPELAYREITNAWQLRGHQLACLQKLAEWRLRQARERDLAVNFVVR
EEHLWQVARYQPTSLGELDSLGLSGQEIRYHGRTLLALVAEGNAVPEDQLPPPIANLIDQPGYKKVFKDIKALIQSVSER
SGLSSELLASRRQINQLLNWHWKLKLSDAQPELLTGWRGDLLSSELLEILQHY

Sequences:

>Translated_373_residues
MNYQLITTNNALQQVCEQARTHAHIALDTEFVRTRTYYPQLGLIQLYDGEQLSLIDPLPITEWQPFRALLQDLNVVKYLH
AGSEDLEVFLNAFDQMPTPMIDTQVLAAFSGRSLSCGFAMLVAEFEGVELDKSESRTDWIARPLSEKQCDYAAADVFYLL
PLAAKLVEATEAAGRMDAAKDECLLLCRRRSETLDPELAYREITNAWQLRGHQLACLQKLAEWRLRQARERDLAVNFVVR
EEHLWQVARYQPTSLGELDSLGLSGQEIRYHGRTLLALVAEGNAVPEDQLPPPIANLIDQPGYKKVFKDIKALIQSVSER
SGLSSELLASRRQINQLLNWHWKLKLSDAQPELLTGWRGDLLSSELLEILQHY
>Mature_373_residues
MNYQLITTNNALQQVCEQARTHAHIALDTEFVRTRTYYPQLGLIQLYDGEQLSLIDPLPITEWQPFRALLQDLNVVKYLH
AGSEDLEVFLNAFDQMPTPMIDTQVLAAFSGRSLSCGFAMLVAEFEGVELDKSESRTDWIARPLSEKQCDYAAADVFYLL
PLAAKLVEATEAAGRMDAAKDECLLLCRRRSETLDPELAYREITNAWQLRGHQLACLQKLAEWRLRQARERDLAVNFVVR
EEHLWQVARYQPTSLGELDSLGLSGQEIRYHGRTLLALVAEGNAVPEDQLPPPIANLIDQPGYKKVFKDIKALIQSVSER
SGLSSELLASRRQINQLLNWHWKLKLSDAQPELLTGWRGDLLSSELLEILQHY

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=373, Percent_Identity=67.828418230563, Blast_Score=531, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 42430; Mature: 42430

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYQLITTNNALQQVCEQARTHAHIALDTEFVRTRTYYPQLGLIQLYDGEQLSLIDPLPI
CCEEEEECCHHHHHHHHHHHHCEEEEECHHHHHHHCCCCCCCEEEEECCCEEEEECCCCC
TEWQPFRALLQDLNVVKYLHAGSEDLEVFLNAFDQMPTPMIDTQVLAAFSGRSLSCGFAM
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHH
LVAEFEGVELDKSESRTDWIARPLSEKQCDYAAADVFYLLPLAAKLVEATEAAGRMDAAK
HHHHHCCCCCCCCCCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DECLLLCRRRSETLDPELAYREITNAWQLRGHQLACLQKLAEWRLRQARERDLAVNFVVR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEE
EEHLWQVARYQPTSLGELDSLGLSGQEIRYHGRTLLALVAEGNAVPEDQLPPPIANLIDQ
HHHHHHHHHCCCCCCCCHHHCCCCCCHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHCC
PGYKKVFKDIKALIQSVSERSGLSSELLASRRQINQLLNWHWKLKLSDAQPELLTGWRGD
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCHH
LLSSELLEILQHY
HHHHHHHHHHHCC
>Mature Secondary Structure
MNYQLITTNNALQQVCEQARTHAHIALDTEFVRTRTYYPQLGLIQLYDGEQLSLIDPLPI
CCEEEEECCHHHHHHHHHHHHCEEEEECHHHHHHHCCCCCCCEEEEECCCEEEEECCCCC
TEWQPFRALLQDLNVVKYLHAGSEDLEVFLNAFDQMPTPMIDTQVLAAFSGRSLSCGFAM
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHH
LVAEFEGVELDKSESRTDWIARPLSEKQCDYAAADVFYLLPLAAKLVEATEAAGRMDAAK
HHHHHCCCCCCCCCCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DECLLLCRRRSETLDPELAYREITNAWQLRGHQLACLQKLAEWRLRQARERDLAVNFVVR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEE
EEHLWQVARYQPTSLGELDSLGLSGQEIRYHGRTLLALVAEGNAVPEDQLPPPIANLIDQ
HHHHHHHHHCCCCCCCCHHHCCCCCCHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHCC
PGYKKVFKDIKALIQSVSERSGLSSELLASRRQINQLLNWHWKLKLSDAQPELLTGWRGD
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCHH
LLSSELLEILQHY
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]