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The map label for this gene is uspE

Identifier: 170024180

GI number: 170024180

Start: 2156947

End: 2157903

Strand: Reverse

Name: uspE

Synonym: YPK_1943

Alternate gene names: 170024180

Gene position: 2157903-2156947 (Counterclockwise)

Preceding gene: 170024181

Following gene: 170024177

Centisome position: 46.02

GC content: 45.56

Gene sequence:

>957_bases
ATGGGAAAGTATCAGAATATTCTGGTTGCTATCGACCCCAATCAGGATGATCAACCTGCATTAAGACGCGCGGTTTATCT
TGTGCAACGCAATGGTGGCACAATCAAAGCATTTTTAGCTATCTATGACCTGTCATATGATATGACCACCTTGCTATCAC
CGGATGAACGCACAGCGATGCGTAAAGGGGTTATCAGCCAGCGTTCAGCTTGGATCAGTGAACAGTGCCGTTTTTATATC
GACTCGGGTATCCCCATTGATATAAAAGTGGTGTGGCATAATCGGCCATACGAAGCCATTATTCAGGAAGTTCTGAAGGC
GAAGCACGATTTATTGCTAAAAATGGCACATCAACACGATCGCCTAGAATCAATTATCTTTACGCCAACTGATTGGCATT
TATTACGTAAATGTCCATGCCCGGTGTGGATGGTAAAAGATCAGCCATGGCCAGAAGAAGGTACCGCGCTGGTGGCGGTG
AATCTCTCAAGTGAAGATCCACTACATGACCCGCTTAATTTACGCTTAGTCAAAGAAACCCTTGAGCTGGCAGAACATGT
CAACCAAACACCCGTTCATCTGATTAGCGCCTACCCAGTGACCCCAATAAATATCGCCATTGAATTACCTGATTTTGACC
CGAGTGTCTATAACGATGCTATTCGTGGTCAGCATTTGGTGGCGATGAAAGCATTGCGCCAACAGTTTGGTATTGATGAA
AAATTCACTCATGTGGAGAAAGGCTTACCTGAAGAGGTGATCCCTGACTTGGCTGAACACCTGAATGCTGGGGTGGTGGT
TTTGGGGACATTGGGCCGTACCGGTTTATCTGCGGCCTTTATCGGTAATACAACTGAGCATGTGATCGATAATTTGAAAT
GTGATTTGCTGGCGATTAAGCCAGAAGGATTTACCTGCCCGATAGAAGGCAATGAAGATCAGGAGGATGCTGAGTAA

Upstream 100 bases:

>100_bases
ACTTATTGGTCTGGTTATCCCTCTCTCACCTATCCTGTTTCTCTATCATGGTTTACTCTTTAACTAACAGACTGTTAATT
CACGGTTGTAAGGAGACGCT

Downstream 100 bases:

>100_bases
CTCCCTTCCAAAGGCCGCCCTACGTAAAATCCTAAAATAAGGGCCACCGAAGTGGCCCTTAGCAATACAATGGATGTTAA
TCAACACATTTTAATTATTC

Product: universal stress protein UspE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MGKYQNILVAIDPNQDDQPALRRAVYLVQRNGGTIKAFLAIYDLSYDMTTLLSPDERTAMRKGVISQRSAWISEQCRFYI
DSGIPIDIKVVWHNRPYEAIIQEVLKAKHDLLLKMAHQHDRLESIIFTPTDWHLLRKCPCPVWMVKDQPWPEEGTALVAV
NLSSEDPLHDPLNLRLVKETLELAEHVNQTPVHLISAYPVTPINIAIELPDFDPSVYNDAIRGQHLVAMKALRQQFGIDE
KFTHVEKGLPEEVIPDLAEHLNAGVVVLGTLGRTGLSAAFIGNTTEHVIDNLKCDLLAIKPEGFTCPIEGNEDQEDAE

Sequences:

>Translated_318_residues
MGKYQNILVAIDPNQDDQPALRRAVYLVQRNGGTIKAFLAIYDLSYDMTTLLSPDERTAMRKGVISQRSAWISEQCRFYI
DSGIPIDIKVVWHNRPYEAIIQEVLKAKHDLLLKMAHQHDRLESIIFTPTDWHLLRKCPCPVWMVKDQPWPEEGTALVAV
NLSSEDPLHDPLNLRLVKETLELAEHVNQTPVHLISAYPVTPINIAIELPDFDPSVYNDAIRGQHLVAMKALRQQFGIDE
KFTHVEKGLPEEVIPDLAEHLNAGVVVLGTLGRTGLSAAFIGNTTEHVIDNLKCDLLAIKPEGFTCPIEGNEDQEDAE
>Mature_317_residues
GKYQNILVAIDPNQDDQPALRRAVYLVQRNGGTIKAFLAIYDLSYDMTTLLSPDERTAMRKGVISQRSAWISEQCRFYID
SGIPIDIKVVWHNRPYEAIIQEVLKAKHDLLLKMAHQHDRLESIIFTPTDWHLLRKCPCPVWMVKDQPWPEEGTALVAVN
LSSEDPLHDPLNLRLVKETLELAEHVNQTPVHLISAYPVTPINIAIELPDFDPSVYNDAIRGQHLVAMKALRQQFGIDEK
FTHVEKGLPEEVIPDLAEHLNAGVVVLGTLGRTGLSAAFIGNTTEHVIDNLKCDLLAIKPEGFTCPIEGNEDQEDAE

Specific function: Required for resistance to DNA-damaging agents

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family

Homologues:

Organism=Escherichia coli, GI1787594, Length=316, Percent_Identity=76.8987341772152, Blast_Score=526, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): USPE_YERPE (Q8ZE81)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AF0280
- RefSeq:   NP_669444.1
- RefSeq:   NP_993420.1
- RefSeq:   YP_002347268.1
- ProteinModelPortal:   Q8ZE81
- GeneID:   1147080
- GeneID:   1175133
- GeneID:   2764945
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO2301
- KEGG:   ypk:y2133
- KEGG:   ypm:YP_2086
- HOGENOM:   HBG638855
- OMA:   YDLSYEM
- ProtClustDB:   PRK11175
- BioCyc:   YPES187410:Y2133-MONOMER
- BioCyc:   YPES214092:YPO2301-MONOMER
- GO:   GO:0005737
- InterPro:   IPR014729
- InterPro:   IPR006016
- Gene3D:   G3DSA:3.40.50.620

Pfam domain/function: PF00582 Usp

EC number: NA

Molecular weight: Translated: 35774; Mature: 35643

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKYQNILVAIDPNQDDQPALRRAVYLVQRNGGTIKAFLAIYDLSYDMTTLLSPDERTAM
CCCCCEEEEEECCCCCCCHHHHHHEEEEECCCCEEEEEEEEEECCCCHHHHCCCCHHHHH
RKGVISQRSAWISEQCRFYIDSGIPIDIKVVWHNRPYEAIIQEVLKAKHDLLLKMAHQHD
HHHHHHHHHHHHHHHCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLESIIFTPTDWHLLRKCPCPVWMVKDQPWPEEGTALVAVNLSSEDPLHDPLNLRLVKET
HHHEEEECCCCHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHH
LELAEHVNQTPVHLISAYPVTPINIAIELPDFDPSVYNDAIRGQHLVAMKALRQQFGIDE
HHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCH
KFTHVEKGLPEEVIPDLAEHLNAGVVVLGTLGRTGLSAAFIGNTTEHVIDNLKCDLLAIK
HHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCHHHHHCCCCEEEEEEC
PEGFTCPIEGNEDQEDAE
CCCEEECCCCCCCCCCCC
>Mature Secondary Structure 
GKYQNILVAIDPNQDDQPALRRAVYLVQRNGGTIKAFLAIYDLSYDMTTLLSPDERTAM
CCCCEEEEEECCCCCCCHHHHHHEEEEECCCCEEEEEEEEEECCCCHHHHCCCCHHHHH
RKGVISQRSAWISEQCRFYIDSGIPIDIKVVWHNRPYEAIIQEVLKAKHDLLLKMAHQHD
HHHHHHHHHHHHHHHCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLESIIFTPTDWHLLRKCPCPVWMVKDQPWPEEGTALVAVNLSSEDPLHDPLNLRLVKET
HHHEEEECCCCHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHH
LELAEHVNQTPVHLISAYPVTPINIAIELPDFDPSVYNDAIRGQHLVAMKALRQQFGIDE
HHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCH
KFTHVEKGLPEEVIPDLAEHLNAGVVVLGTLGRTGLSAAFIGNTTEHVIDNLKCDLLAIK
HHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCHHHHHCCCCEEEEEEC
PEGFTCPIEGNEDQEDAE
CCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430