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The map label for this gene is marC [H]

Identifier: 170024056

GI number: 170024056

Start: 2016072

End: 2016755

Strand: Reverse

Name: marC [H]

Synonym: YPK_1817

Alternate gene names: 170024056

Gene position: 2016755-2016072 (Counterclockwise)

Preceding gene: 170024058

Following gene: 170024054

Centisome position: 43.01

GC content: 43.86

Gene sequence:

>684_bases
ATGCTAAGTATTTTCGAATTATTTAAAGCCGTTGGCTTAGGATTAGTATTGCTGCTGCCATTGGCAAATCCACTGACGAC
GGTGGCCTTATTGCTAGGGTTATCCGGTAATATGACCCGCGAGGAGCGTAATAATCAGTCGTTAATGGCGGCAATTTATG
TCTTCTTTATCATGACTATCGCGTTTTATGCCGGTCAGATCGTCATGAGTACATTTGGTATCTCTATTCCCGGTCTGCGT
ATAGCTGGTGGCTTAATTGTCGCGTTTATTGGTTTTCGTATGCTCTTTCCGCAACAATCGGCTGAAGATACTCAACTGGA
GGCAAAATCCCAGGATTTAAAAAAACGTAAATCCATCAATATTGCCTTTGTACCGCTGGCAATGCCGAGTACTGCGGGGC
CAGGTACGATTGCAATGATCATCAGTTCCGCTGCAACAATGAAAGACCAGACAATGTTTGCACCATGGGTATTGGCCATC
GCCCCCGTAATCACATTCTTATGCGTTTCGTTGATTTTGTGGGGATCTTTACTCAGCTCAGGAGCGATTATGCGCTGGGT
TGGTAAAAGCGGTATTGAAGCAATTTCACGTTTGATGGGATTCTTGCTGGTATGTATGGGTGTGCAATTTATTATTAATG
GCGTCTTAGAGTTGATCTCAACTTATCAACCTGTCATGGCTTAA

Upstream 100 bases:

>100_bases
AATAATACTCTTCACACAAGTAAGTTAAGCTGGTGTATGAATTATTGCCTGATATCGTTTTTTTTCGGGTTTGATTGATG
TTATTTGCGGAGTAGGATCC

Downstream 100 bases:

>100_bases
ATATCAAGACTCAGTAAATATAATTTCAAAGTAAAATAAAAAAGTAACTTGCCGTAAAATTTAAAGTAAACGCTAGCCGA
TGCTACACCATCCATAGGCT

Product: multiple drug resistance protein MarC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MLSIFELFKAVGLGLVLLLPLANPLTTVALLLGLSGNMTREERNNQSLMAAIYVFFIMTIAFYAGQIVMSTFGISIPGLR
IAGGLIVAFIGFRMLFPQQSAEDTQLEAKSQDLKKRKSINIAFVPLAMPSTAGPGTIAMIISSAATMKDQTMFAPWVLAI
APVITFLCVSLILWGSLLSSGAIMRWVGKSGIEAISRLMGFLLVCMGVQFIINGVLELISTYQPVMA

Sequences:

>Translated_227_residues
MLSIFELFKAVGLGLVLLLPLANPLTTVALLLGLSGNMTREERNNQSLMAAIYVFFIMTIAFYAGQIVMSTFGISIPGLR
IAGGLIVAFIGFRMLFPQQSAEDTQLEAKSQDLKKRKSINIAFVPLAMPSTAGPGTIAMIISSAATMKDQTMFAPWVLAI
APVITFLCVSLILWGSLLSSGAIMRWVGKSGIEAISRLMGFLLVCMGVQFIINGVLELISTYQPVMA
>Mature_227_residues
MLSIFELFKAVGLGLVLLLPLANPLTTVALLLGLSGNMTREERNNQSLMAAIYVFFIMTIAFYAGQIVMSTFGISIPGLR
IAGGLIVAFIGFRMLFPQQSAEDTQLEAKSQDLKKRKSINIAFVPLAMPSTAGPGTIAMIISSAATMKDQTMFAPWVLAI
APVITFLCVSLILWGSLLSSGAIMRWVGKSGIEAISRLMGFLLVCMGVQFIINGVLELISTYQPVMA

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=221, Percent_Identity=73.7556561085973, Blast_Score=307, Evalue=3e-85,
Organism=Escherichia coli, GI1787494, Length=198, Percent_Identity=31.3131313131313, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1789842, Length=205, Percent_Identity=24.8780487804878, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 24429; Mature: 24429

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIFELFKAVGLGLVLLLPLANPLTTVALLLGLSGNMTREERNNQSLMAAIYVFFIMTI
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHH
AFYAGQIVMSTFGISIPGLRIAGGLIVAFIGFRMLFPQQSAEDTQLEAKSQDLKKRKSIN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
IAFVPLAMPSTAGPGTIAMIISSAATMKDQTMFAPWVLAIAPVITFLCVSLILWGSLLSS
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAIMRWVGKSGIEAISRLMGFLLVCMGVQFIINGVLELISTYQPVMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSIFELFKAVGLGLVLLLPLANPLTTVALLLGLSGNMTREERNNQSLMAAIYVFFIMTI
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHH
AFYAGQIVMSTFGISIPGLRIAGGLIVAFIGFRMLFPQQSAEDTQLEAKSQDLKKRKSIN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
IAFVPLAMPSTAGPGTIAMIISSAATMKDQTMFAPWVLAIAPVITFLCVSLILWGSLLSS
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAIMRWVGKSGIEAISRLMGFLLVCMGVQFIINGVLELISTYQPVMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA