| Definition | Yersinia pseudotuberculosis YPIII chromosome, complete genome. |
|---|---|
| Accession | NC_010465 |
| Length | 4,689,441 |
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The map label for this gene is kduD [H]
Identifier: 170024042
GI number: 170024042
Start: 2004357
End: 2005118
Strand: Reverse
Name: kduD [H]
Synonym: YPK_1803
Alternate gene names: 170024042
Gene position: 2005118-2004357 (Counterclockwise)
Preceding gene: 170024043
Following gene: 170024041
Centisome position: 42.76
GC content: 48.82
Gene sequence:
>762_bases ATGATTTTAGATTCCTTTGAATTGAAAGGTAAAGTTGCGCTGGTGACTGGTTGCGATACTGGCTTAGGCCAAGGCATGGC GATCGGTTTAGCAGAAGCGGGTTGCGATATCATCGGCGTGAATATTGTCGAGCCACGTGAGACTATCGAACAAGTGACTG CACTGGGCCGTCGCTTTTTCAGCCTGACCGCTGACCTGAGCAACATTGAATGCATCCCTTCCCTATTAGAGCGTGCTGTC GCTGAATTTGGCCATATTGATATTCTGGTCAACAACGCGGGGATCATCCGCCGTGAAGATGCCATTAATTTCAGCGAAAA GGACTGGGACGATGTCATGAACGTTAACATCAAGTCTGTGTTCTTTATGTCCCAAGCGGTTGCTAAACAGTTTATTAAAC AAGGTAATGGCGGCAAAATTATTAACGTTGCCTCGATGCTGTCTTACCAAGGGGGGATTCGTGTCCCTTCTTATACTGCC TCGAAAAGTGCCGTCATGGGCGTGACCCGTCTGTTAGCCAACGAATGGGCAAAGCACGGCATCAATGTCAACGCGGTCGC TCCAGGTTATATGGCAACCAATAACACCCAGCAGTTGCGTAAAGATGAAGAGCGTAGCAAAGAGATCCTTGACCGTATCC CGGCTGGCCGTTGGGGCTTACCTGATGATCTGAAAGGCCCAGTAGTCTTCCTGGCCTCTAAAGCATCTGATTATATCAGC GGTTATACTATCGCCGTTGATGGCGGTTGGTTAGCACGATAA
Upstream 100 bases:
>100_bases CTGCGTTAAGTATCACCTATTAAAGCCACCTTTACGGCGGCTTTCACCTCCAATAATGAAATCGCGGTCATCGTTGACCG CCTTGAGAGAGATTTTAGCT
Downstream 100 bases:
>100_bases ACCACCATCTACTATCCACTTATCCACTATCGCGATTAATTTGAGTTAACACGACTTATCTACCTTATTGTGACATTCAA CTCAAAAACGCATCAGGCAC
Product: 2-deoxy-D-gluconate 3-dehydrogenase
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 253; Mature: 253
Protein sequence:
>253_residues MILDSFELKGKVALVTGCDTGLGQGMAIGLAEAGCDIIGVNIVEPRETIEQVTALGRRFFSLTADLSNIECIPSLLERAV AEFGHIDILVNNAGIIRREDAINFSEKDWDDVMNVNIKSVFFMSQAVAKQFIKQGNGGKIINVASMLSYQGGIRVPSYTA SKSAVMGVTRLLANEWAKHGINVNAVAPGYMATNNTQQLRKDEERSKEILDRIPAGRWGLPDDLKGPVVFLASKASDYIS GYTIAVDGGWLAR
Sequences:
>Translated_253_residues MILDSFELKGKVALVTGCDTGLGQGMAIGLAEAGCDIIGVNIVEPRETIEQVTALGRRFFSLTADLSNIECIPSLLERAV AEFGHIDILVNNAGIIRREDAINFSEKDWDDVMNVNIKSVFFMSQAVAKQFIKQGNGGKIINVASMLSYQGGIRVPSYTA SKSAVMGVTRLLANEWAKHGINVNAVAPGYMATNNTQQLRKDEERSKEILDRIPAGRWGLPDDLKGPVVFLASKASDYIS GYTIAVDGGWLAR >Mature_253_residues MILDSFELKGKVALVTGCDTGLGQGMAIGLAEAGCDIIGVNIVEPRETIEQVTALGRRFFSLTADLSNIECIPSLLERAV AEFGHIDILVNNAGIIRREDAINFSEKDWDDVMNVNIKSVFFMSQAVAKQFIKQGNGGKIINVASMLSYQGGIRVPSYTA SKSAVMGVTRLLANEWAKHGINVNAVAPGYMATNNTQQLRKDEERSKEILDRIPAGRWGLPDDLKGPVVFLASKASDYIS GYTIAVDGGWLAR
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=33.8582677165354, Blast_Score=144, Evalue=1e-34, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=32.8, Blast_Score=120, Evalue=9e-28, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=30.6451612903226, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=29.9610894941634, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=30.5220883534137, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=29.2490118577075, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=30.9917355371901, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=29.2490118577075, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=28.9156626506024, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI4503301, Length=253, Percent_Identity=28.8537549407115, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=29.3814432989691, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI31542939, Length=213, Percent_Identity=29.1079812206573, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI4758504, Length=198, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=28.6307053941909, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI142976729, Length=219, Percent_Identity=27.8538812785388, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI33667109, Length=201, Percent_Identity=28.3582089552239, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI59889578, Length=194, Percent_Identity=26.8041237113402, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI209862901, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI19923983, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI40254986, Length=199, Percent_Identity=27.1356783919598, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI210032110, Length=193, Percent_Identity=27.4611398963731, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=30.0546448087432, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=29.6511627906977, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI7706318, Length=204, Percent_Identity=28.921568627451, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI83715985, Length=186, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4504503, Length=211, Percent_Identity=29.3838862559242, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=84.5849802371542, Blast_Score=456, Evalue=1e-130, Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=42.96875, Blast_Score=198, Evalue=3e-52, Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=40.4, Blast_Score=179, Evalue=2e-46, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=37.3983739837398, Blast_Score=156, Evalue=1e-39, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=34.136546184739, Blast_Score=139, Evalue=2e-34, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=33.0708661417323, Blast_Score=124, Evalue=4e-30, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=31.0483870967742, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=28.968253968254, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=29.2, Blast_Score=101, Evalue=6e-23, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=30.952380952381, Blast_Score=88, Evalue=4e-19, Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=26.5625, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787526, Length=228, Percent_Identity=27.6315789473684, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI2367365, Length=177, Percent_Identity=30.5084745762712, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787820, Length=193, Percent_Identity=28.4974093264249, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1788891, Length=222, Percent_Identity=29.2792792792793, Blast_Score=61, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=32.9268292682927, Blast_Score=129, Evalue=2e-30, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=32.6530612244898, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=35.1778656126482, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=29.8804780876494, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=30.6451612903226, Blast_Score=113, Evalue=8e-26, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=31.1284046692607, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=31.5789473684211, Blast_Score=111, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=32.5670498084291, Blast_Score=110, Evalue=8e-25, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=30.952380952381, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=30.0751879699248, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=31.0344827586207, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=34.2307692307692, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=30.7692307692308, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=30.2325581395349, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=31.1787072243346, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=29.8449612403101, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17563726, Length=271, Percent_Identity=29.520295202952, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=31.3953488372093, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=30.1526717557252, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=30.2325581395349, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=31.203007518797, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=29.6875, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=32.9457364341085, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17538486, Length=258, Percent_Identity=29.4573643410853, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=27.906976744186, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=28.735632183908, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=27.906976744186, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=30.9803921568627, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17536651, Length=265, Percent_Identity=26.4150943396226, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=28.4263959390863, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=29.3193717277487, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=29.1666666666667, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17561272, Length=178, Percent_Identity=27.5280898876405, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=25.7894736842105, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI32563809, Length=208, Percent_Identity=27.4038461538462, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17507613, Length=208, Percent_Identity=27.4038461538462, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=27.1653543307087, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17555612, Length=220, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=6e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=26.8, Blast_Score=82, Evalue=8e-17, Organism=Saccharomyces cerevisiae, GI6322861, Length=235, Percent_Identity=29.3617021276596, Blast_Score=82, Evalue=8e-17, Organism=Saccharomyces cerevisiae, GI6323882, Length=248, Percent_Identity=27.8225806451613, Blast_Score=72, Evalue=8e-14, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=34.0080971659919, Blast_Score=139, Evalue=2e-33, Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=31.2252964426877, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=32.295719844358, Blast_Score=114, Evalue=5e-26, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=30.4, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=30.6122448979592, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=29.6, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24644337, Length=210, Percent_Identity=30.4761904761905, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI21358495, Length=202, Percent_Identity=30.1980198019802, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI18859837, Length=187, Percent_Identity=31.5508021390374, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=28.515625, Blast_Score=84, Evalue=6e-17, Organism=Drosophila melanogaster, GI21357673, Length=198, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24649181, Length=197, Percent_Identity=28.9340101522843, Blast_Score=81, Evalue=8e-16, Organism=Drosophila melanogaster, GI221331218, Length=224, Percent_Identity=29.0178571428571, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24665243, Length=224, Percent_Identity=29.0178571428571, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI221331216, Length=222, Percent_Identity=29.2792792792793, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24665247, Length=224, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24640492, Length=215, Percent_Identity=26.5116279069767, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI28571387, Length=210, Percent_Identity=27.1428571428571, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI281364892, Length=172, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24580925, Length=200, Percent_Identity=25, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 27395; Mature: 27395
Theoretical pI: Translated: 5.40; Mature: 5.40
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MILDSFELKGKVALVTGCDTGLGQGMAIGLAEAGCDIIGVNIVEPRETIEQVTALGRRFF CCCCCCCCCCCEEEEEECCCCCCCCEEEEHHHCCCCEEEEEEECHHHHHHHHHHHHHHHH SLTADLSNIECIPSLLERAVAEFGHIDILVNNAGIIRREDAINFSEKDWDDVMNVNIKSV HHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCHHHHHCCCHHHH FFMSQAVAKQFIKQGNGGKIINVASMLSYQGGIRVPSYTASKSAVMGVTRLLANEWAKHG HHHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC INVNAVAPGYMATNNTQQLRKDEERSKEILDRIPAGRWGLPDDLKGPVVFLASKASDYIS CCEEEECCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHC GYTIAVDGGWLAR CEEEEECCCCCCC >Mature Secondary Structure MILDSFELKGKVALVTGCDTGLGQGMAIGLAEAGCDIIGVNIVEPRETIEQVTALGRRFF CCCCCCCCCCCEEEEEECCCCCCCCEEEEHHHCCCCEEEEEEECHHHHHHHHHHHHHHHH SLTADLSNIECIPSLLERAVAEFGHIDILVNNAGIIRREDAINFSEKDWDDVMNVNIKSV HHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCHHHHHCCCHHHH FFMSQAVAKQFIKQGNGGKIINVASMLSYQGGIRVPSYTASKSAVMGVTRLLANEWAKHG HHHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC INVNAVAPGYMATNNTQQLRKDEERSKEILDRIPAGRWGLPDDLKGPVVFLASKASDYIS CCEEEECCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHC GYTIAVDGGWLAR CEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9278503; 2836407; 1766386 [H]