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The map label for this gene is glnH [H]

Identifier: 170023841

GI number: 170023841

Start: 1769642

End: 1770385

Strand: Reverse

Name: glnH [H]

Synonym: YPK_1600

Alternate gene names: 170023841

Gene position: 1770385-1769642 (Counterclockwise)

Preceding gene: 170023842

Following gene: 170023840

Centisome position: 37.75

GC content: 46.1

Gene sequence:

>744_bases
ATGAAGTCACTTGTCAAAGTTTCATTGGCCGCACTGGCGCTGGCCTTTGCTGTTAGCGCCTACGCCGCAGAAAAAGAGTT
AATTGTTGCTACAGACACCGCTTTCGTCCCATTTGAATTCAAACAAGGGGATAAATACGTTGGTTTTGATATCGATTTGT
GGGATGCCATCGCGAAAAAACTGGATCTGAAGTACACGCTAAAACCAATGGATTTCAGCGGTATCATTCCGGCGCTGCAA
ACGAAGAATGTCGATCTGGCACTGGCGGGCATTACTATCACCGATGAGCGTAAAAAAGCCGTTGATTTTTCTGATGGTTA
TTACAACAGCGGCCTCTTGGTCATGGTAAAAGCGGATAATAATGACATTAAAAGTGAGGCCGACCTGCAAGGCAAAGTGT
TAGCAGTGAAGAGCGGCACTGGCTCGGTGGATTACGCCAAAGCCAATATCAAGACCAAAGACTTGCGCCAATTCCCGAAT
ATCGATAACGCCTACCTGGAATTAGGAACTGGCCGTGCAGATGCGGTTTTACATGATACGCCGAATATTCTTTACTTCAT
CAAAACCGCAGGTAATGGCCAGTTCAAAGCAGTAGGTGAGTCGATTAAAGCTCAGCAGTACGGTGTTGCATTCCCGCAAG
GCAGTGACCTGCGTGAAAAAGTTAACGCGGCACTGAAATCTCTGAAAGAAGACGGCACTTACGCTGAAATCTATAAAAAA
TGGTTCGGCGTAGAACCTAAGTAA

Upstream 100 bases:

>100_bases
AATATATCAGTAAATTGGATAAGTAGGTGGTGCTGCTCGTCGCGCTGCAATCTCAAGTAAAGGAGGGTATCTCCATAAAA
GCACAAAGGAATTCCCACTT

Downstream 100 bases:

>100_bases
TTTATTTTGCCGTATTTATATCAGGAGACTATCCATGCAGTTTGAATGGAGCGCTATTTGGCCCGCCATCCCACTTCTGC
TTGAAGGTGCCAAGTTGACC

Product: glutamine ABC transporter periplasmic protein

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: GlnBP [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKSLVKVSLAALALAFAVSAYAAEKELIVATDTAFVPFEFKQGDKYVGFDIDLWDAIAKKLDLKYTLKPMDFSGIIPALQ
TKNVDLALAGITITDERKKAVDFSDGYYNSGLLVMVKADNNDIKSEADLQGKVLAVKSGTGSVDYAKANIKTKDLRQFPN
IDNAYLELGTGRADAVLHDTPNILYFIKTAGNGQFKAVGESIKAQQYGVAFPQGSDLREKVNAALKSLKEDGTYAEIYKK
WFGVEPK

Sequences:

>Translated_247_residues
MKSLVKVSLAALALAFAVSAYAAEKELIVATDTAFVPFEFKQGDKYVGFDIDLWDAIAKKLDLKYTLKPMDFSGIIPALQ
TKNVDLALAGITITDERKKAVDFSDGYYNSGLLVMVKADNNDIKSEADLQGKVLAVKSGTGSVDYAKANIKTKDLRQFPN
IDNAYLELGTGRADAVLHDTPNILYFIKTAGNGQFKAVGESIKAQQYGVAFPQGSDLREKVNAALKSLKEDGTYAEIYKK
WFGVEPK
>Mature_247_residues
MKSLVKVSLAALALAFAVSAYAAEKELIVATDTAFVPFEFKQGDKYVGFDIDLWDAIAKKLDLKYTLKPMDFSGIIPALQ
TKNVDLALAGITITDERKKAVDFSDGYYNSGLLVMVKADNNDIKSEADLQGKVLAVKSGTGSVDYAKANIKTKDLRQFPN
IDNAYLELGTGRADAVLHDTPNILYFIKTAGNGQFKAVGESIKAQQYGVAFPQGSDLREKVNAALKSLKEDGTYAEIYKK
WFGVEPK

Specific function: Involved in a glutamine-transport system glnHPQ [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1787031, Length=248, Percent_Identity=85.0806451612903, Blast_Score=432, Evalue=1e-123,
Organism=Escherichia coli, GI1788228, Length=257, Percent_Identity=34.2412451361868, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787088, Length=245, Percent_Identity=35.9183673469388, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1787085, Length=249, Percent_Identity=34.9397590361446, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788649, Length=254, Percent_Identity=34.251968503937, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788648, Length=230, Percent_Identity=30.4347826086957, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: 1440 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 460 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR005768
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 26952; Mature: 26952

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLVKVSLAALALAFAVSAYAAEKELIVATDTAFVPFEFKQGDKYVGFDIDLWDAIAKK
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEECCCCEEEEEEEHHHHHHHHH
LDLKYTLKPMDFSGIIPALQTKNVDLALAGITITDERKKAVDFSDGYYNSGLLVMVKADN
CCCEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCCHHEECCCCCEECCCEEEEEECCC
NDIKSEADLQGKVLAVKSGTGSVDYAKANIKTKDLRQFPNIDNAYLELGTGRADAVLHDT
CCCCCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHCCCCCCEEEEECCCCCCEEEECC
PNILYFIKTAGNGQFKAVGESIKAQQYGVAFPQGSDLREKVNAALKSLKEDGTYAEIYKK
CCEEEEEEECCCCEEEEHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
WFGVEPK
HHCCCCC
>Mature Secondary Structure
MKSLVKVSLAALALAFAVSAYAAEKELIVATDTAFVPFEFKQGDKYVGFDIDLWDAIAKK
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEECCCCEEEEEEEHHHHHHHHH
LDLKYTLKPMDFSGIIPALQTKNVDLALAGITITDERKKAVDFSDGYYNSGLLVMVKADN
CCCEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCCHHEECCCCCEECCCEEEEEECCC
NDIKSEADLQGKVLAVKSGTGSVDYAKANIKTKDLRQFPNIDNAYLELGTGRADAVLHDT
CCCCCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHCCCCCCEEEEECCCCCCEEEECC
PNILYFIKTAGNGQFKAVGESIKAQQYGVAFPQGSDLREKVNAALKSLKEDGTYAEIYKK
CCEEEEEEECCCCEEEEHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
WFGVEPK
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: Translocates substrate across the membrane [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]