Click here to switch to the map view.

The map label for this gene is yhjH [H]

Identifier: 170023784

GI number: 170023784

Start: 1705207

End: 1705899

Strand: Direct

Name: yhjH [H]

Synonym: YPK_1543

Alternate gene names: 170023784

Gene position: 1705207-1705899 (Clockwise)

Preceding gene: 170023782

Following gene: 170023785

Centisome position: 36.36

GC content: 40.12

Gene sequence:

>693_bases
ATGAAGCTAAATATCAAAGTTAATTGTTCTTATGTCTGTGAACCCATACGTAAGCAAGACGGCAGCTTATTGGCAGTAGA
ATTGTTAAGCCGATTTTCAGCGACACCCGTTGATTTACCTATTGATGTCGAAAAATTTATTAATGAATTGGACATAAACG
GAAAAAACGATTTATTCCAAAATCAATTGCAGGCGGTAAAAGCCTACAGTGATTGGTTTATCACGAACAATGTCCTGCTG
TCGATCAATATTGATTTTGATTTAGCGAGTGTGATTGTTACTGATGCGCCCACCCGGCAGTTGCTGGATGAAATGCCTTT
TTTACGGCTGGAAATCATGGAGACATTCTCCAATTTATCCGATGGTATGAATAATCCCTTGCTACGTGAGTTAGCCTCAC
TGTATCCATTATGGTTGGATGATTTAGGCAGCGGAGGCTCAACATTGAACGCGGTGACTGCCAATATCTTTGAATATATA
AAAATTGATAAGCATTTCTTCTGGCAGCACAACAAACATACCTTCCCGATATTGATCAACAACATTAAAAAATATTGTCT
TGGGGTCATTGTTGTCGGGGTAGAAAATCAGGGGGAGTCTGAGCAACTCGCAGGCAGTAATATTGATGCTATGCAGGGGT
ATCTATTTAACCCGATGACATTGGATGAGCTAGTCTCCCAACCTTTGCGTTAA

Upstream 100 bases:

>100_bases
AATGTTAGGCGTTTAATAAAAGATTAGCGATAGTTTATCAATCCTCCTGCTGAGATCGGATAACGATCTTACTGTTATCT
ATATACTTTTCCAGGTGCGT

Downstream 100 bases:

>100_bases
TGTTTTTGGCAAAGCGCGCCTTGATAGGCTGTATCGCGCGGGTATTCGTCTGGGCTGTCAGCGCGATCCTTTTCGACAAA
ATTTTCTCATGGTAGATACT

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKLNIKVNCSYVCEPIRKQDGSLLAVELLSRFSATPVDLPIDVEKFINELDINGKNDLFQNQLQAVKAYSDWFITNNVLL
SINIDFDLASVIVTDAPTRQLLDEMPFLRLEIMETFSNLSDGMNNPLLRELASLYPLWLDDLGSGGSTLNAVTANIFEYI
KIDKHFFWQHNKHTFPILINNIKKYCLGVIVVGVENQGESEQLAGSNIDAMQGYLFNPMTLDELVSQPLR

Sequences:

>Translated_230_residues
MKLNIKVNCSYVCEPIRKQDGSLLAVELLSRFSATPVDLPIDVEKFINELDINGKNDLFQNQLQAVKAYSDWFITNNVLL
SINIDFDLASVIVTDAPTRQLLDEMPFLRLEIMETFSNLSDGMNNPLLRELASLYPLWLDDLGSGGSTLNAVTANIFEYI
KIDKHFFWQHNKHTFPILINNIKKYCLGVIVVGVENQGESEQLAGSNIDAMQGYLFNPMTLDELVSQPLR
>Mature_230_residues
MKLNIKVNCSYVCEPIRKQDGSLLAVELLSRFSATPVDLPIDVEKFINELDINGKNDLFQNQLQAVKAYSDWFITNNVLL
SINIDFDLASVIVTDAPTRQLLDEMPFLRLEIMETFSNLSDGMNNPLLRELASLYPLWLDDLGSGGSTLNAVTANIFEYI
KIDKHFFWQHNKHTFPILINNIKKYCLGVIVVGVENQGESEQLAGSNIDAMQGYLFNPMTLDELVSQPLR

Specific function: A bis-(3'-5') cyclic diguanylic acid (c-di-GMP) phosphodiesterase involved in regulating the levels of c-di-GMP that control cell motility (the flagella) and adhesion (adhesive curli fimbriae). The YhjH effect on flagella is controlled via the c-di-GMP-bi

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI87082280, Length=225, Percent_Identity=26.6666666666667, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788000, Length=224, Percent_Identity=27.2321428571429, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 26002; Mature: 26002

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNIKVNCSYVCEPIRKQDGSLLAVELLSRFSATPVDLPIDVEKFINELDINGKNDLFQ
CEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHH
NQLQAVKAYSDWFITNNVLLSINIDFDLASVIVTDAPTRQLLDEMPFLRLEIMETFSNLS
HHHHHHHHHHCEEEECCEEEEEEECCEEEEHEECCCCHHHHHHHCCHHHHHHHHHHHHHH
DGMNNPLLRELASLYPLWLDDLGSGGSTLNAVTANIFEYIKIDKHFFWQHNKHTFPILIN
CCCCCHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHH
NIKKYCLGVIVVGVENQGESEQLAGSNIDAMQGYLFNPMTLDELVSQPLR
HHHHHHHEEEEEEECCCCCCHHHCCCCCHHHHCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MKLNIKVNCSYVCEPIRKQDGSLLAVELLSRFSATPVDLPIDVEKFINELDINGKNDLFQ
CEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHH
NQLQAVKAYSDWFITNNVLLSINIDFDLASVIVTDAPTRQLLDEMPFLRLEIMETFSNLS
HHHHHHHHHHCEEEECCEEEEEEECCEEEEHEECCCCHHHHHHHCCHHHHHHHHHHHHHH
DGMNNPLLRELASLYPLWLDDLGSGGSTLNAVTANIFEYIKIDKHFFWQHNKHTFPILIN
CCCCCHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHH
NIKKYCLGVIVVGVENQGESEQLAGSNIDAMQGYLFNPMTLDELVSQPLR
HHHHHHHEEEEEEECCCCCCHHHCCCCCHHHHCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]