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The map label for this gene is aroC [H]

Identifier: 170023755

GI number: 170023755

Start: 1675831

End: 1676916

Strand: Direct

Name: aroC [H]

Synonym: YPK_1514

Alternate gene names: 170023755

Gene position: 1675831-1676916 (Clockwise)

Preceding gene: 170023754

Following gene: 170023756

Centisome position: 35.74

GC content: 52.12

Gene sequence:

>1086_bases
ATGGCTGGGAACAGTATTGGGCAGTTTTTCCGCGTCACCACTTTTGGTGAATCTCACGGTATCGCCCTAGGATGCATTAT
TGATGGTGTACCACCGGGCATTCCGATTACCGAGGCTGATATTCAGTTGGATCTTGACCGTCGCCGTCCGGGGACTTCTC
GTTATACCACTCAGCGCCGTGAGCTGGATCAAGTTCGCATTTTATCCGGCGTATTTGAGGGCGTCACTACGGGGACCAGT
ATCGGGTTAATGATTGAAAATACGGATCAGCGTTCGCAAGATTACAGCGCAATTAAAGATGTGTTCCGCCCCGGTCATGC
TGATTATACCTATGAGCAAAAATACGGTGTACGGGATTACCGTGGTGGTGGCCGCTCTTCAGCCCGCGAAACCGCGATGC
GGGTGGCGGCGGGCGCTATTGCTAAAAAGTATTTAGCACAAAAATTTGGTGTACAGGTGCGTGGTTATCTGGCGCAAATG
GGGGATGTTAGTTGTGATTTGCTCGATTGGGATTTGGTCGAGCAAAATCCATTCTTTTGCCCCGATGCCAGCAAACTGGA
GCCGCTGGATGCCCTAATGCGTGAGCTGAAAAAAGCCGGTGACTCCATTGGTGCCAAAATCACCGTCGTCGCTGAAAATG
TCCCCGTAGGTTTAGGTGAGCCGGTATTTGATCGTTTGGATGCGGATCTTGCTCATGCATTGATGAGTATCAACGCGGTA
AAAGGGGTGGAAATTGGCGATGGTTTTGCTGTCGTCACTAAGCGTGGCAGTGAAAACCGTGATGAAATTACTCCGCAGGG
CTTCCAAAGTAATCATGCTGGCGGCATTTTAGGGGGGATTAGCAGCGGGCAGCCGGTTGTTGCTCACATTGCATTAAAAC
CCACCTCCAGCATTATGGTTCCGGGGCAAACTATCAATCGGCAAGGAGAAGCGGTTGAAATGGTGACCCGAGGGCGTCAT
GACCCGTGTGTGGGTATCCGGGCGGTACCTATTGCAGAAGCGATGATGGCTATCGTACTTATGGATCACCTACTGCGCCA
GCGCGCGCAGTGCGGCGATGTGGCTTCAGACGTTCCGCGCTGGTAG

Upstream 100 bases:

>100_bases
CATTTCAGCATGTATCGTGATTAATTGATCACTTCTTATCAAGTCTGTCAGTACGGTTAATCTCTATCTGGCAGACCGCT
TATGACTCAAAGGAGCCGTG

Downstream 100 bases:

>100_bases
ATAGCATGAAAAATTGGATAGTGGGTATGGTGGCGTTGGTCACCATGGTCCCTGTCATGGCGGCCACGCCATGGCAAAAG
ATTACGCACCCGGTGGCGGG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAGNSIGQFFRVTTFGESHGIALGCIIDGVPPGIPITEADIQLDLDRRRPGTSRYTTQRRELDQVRILSGVFEGVTTGTS
IGLMIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLAQKFGVQVRGYLAQM
GDVSCDLLDWDLVEQNPFFCPDASKLEPLDALMRELKKAGDSIGAKITVVAENVPVGLGEPVFDRLDADLAHALMSINAV
KGVEIGDGFAVVTKRGSENRDEITPQGFQSNHAGGILGGISSGQPVVAHIALKPTSSIMVPGQTINRQGEAVEMVTRGRH
DPCVGIRAVPIAEAMMAIVLMDHLLRQRAQCGDVASDVPRW

Sequences:

>Translated_361_residues
MAGNSIGQFFRVTTFGESHGIALGCIIDGVPPGIPITEADIQLDLDRRRPGTSRYTTQRRELDQVRILSGVFEGVTTGTS
IGLMIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLAQKFGVQVRGYLAQM
GDVSCDLLDWDLVEQNPFFCPDASKLEPLDALMRELKKAGDSIGAKITVVAENVPVGLGEPVFDRLDADLAHALMSINAV
KGVEIGDGFAVVTKRGSENRDEITPQGFQSNHAGGILGGISSGQPVVAHIALKPTSSIMVPGQTINRQGEAVEMVTRGRH
DPCVGIRAVPIAEAMMAIVLMDHLLRQRAQCGDVASDVPRW
>Mature_360_residues
AGNSIGQFFRVTTFGESHGIALGCIIDGVPPGIPITEADIQLDLDRRRPGTSRYTTQRRELDQVRILSGVFEGVTTGTSI
GLMIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLAQKFGVQVRGYLAQMG
DVSCDLLDWDLVEQNPFFCPDASKLEPLDALMRELKKAGDSIGAKITVVAENVPVGLGEPVFDRLDADLAHALMSINAVK
GVEIGDGFAVVTKRGSENRDEITPQGFQSNHAGGILGGISSGQPVVAHIALKPTSSIMVPGQTINRQGEAVEMVTRGRHD
PCVGIRAVPIAEAMMAIVLMDHLLRQRAQCGDVASDVPRW

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=361, Percent_Identity=83.6565096952909, Blast_Score=611, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=44.9591280653951, Blast_Score=308, Evalue=9e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 38983; Mature: 38852

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSIGQFFRVTTFGESHGIALGCIIDGVPPGIPITEADIQLDLDRRRPGTSRYTTQRR
CCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCEECCCEEEEECCCCCCCCHHHHHHH
ELDQVRILSGVFEGVTTGTSIGLMIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGVRDY
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEHHCCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLAQKFGVQVRGYLAQMGDVSCDLLDWDLVEQNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCHHHCCCCCCC
PDASKLEPLDALMRELKKAGDSIGAKITVVAENVPVGLGEPVFDRLDADLAHALMSINAV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVVTKRGSENRDEITPQGFQSNHAGGILGGISSGQPVVAHIALKPTSSIMV
CCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCEEE
PGQTINRQGEAVEMVTRGRHDPCVGIRAVPIAEAMMAIVLMDHLLRQRAQCGDVASDVPR
CCHHHCCCCCCHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCC
W
C
>Mature Secondary Structure 
AGNSIGQFFRVTTFGESHGIALGCIIDGVPPGIPITEADIQLDLDRRRPGTSRYTTQRR
CCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCEECCCEEEEECCCCCCCCHHHHHHH
ELDQVRILSGVFEGVTTGTSIGLMIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGVRDY
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEHHCCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLAQKFGVQVRGYLAQMGDVSCDLLDWDLVEQNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCHHHCCCCCCC
PDASKLEPLDALMRELKKAGDSIGAKITVVAENVPVGLGEPVFDRLDADLAHALMSINAV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVVTKRGSENRDEITPQGFQSNHAGGILGGISSGQPVVAHIALKPTSSIMV
CCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCEEE
PGQTINRQGEAVEMVTRGRHDPCVGIRAVPIAEAMMAIVLMDHLLRQRAQCGDVASDVPR
CCHHHCCCCCCHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCC
W
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA