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The map label for this gene is sixA [H]

Identifier: 170023752

GI number: 170023752

Start: 1673194

End: 1673670

Strand: Direct

Name: sixA [H]

Synonym: YPK_1511

Alternate gene names: 170023752

Gene position: 1673194-1673670 (Clockwise)

Preceding gene: 170023751

Following gene: 170023754

Centisome position: 35.68

GC content: 51.78

Gene sequence:

>477_bases
ATGCGTCACGGTGACGCGGCACTTGATGCCGCTAGTGATGCGCAAAGGCCTCTAACTCTGTGTGGTCAGGATGAATCACG
TCAGATAGCAAGCTGGCTAAGTGAGCAGTCAGTGGATATCGATCAGATTCTGGTTAGCCCTTATTTACGTGCCAGACAAA
CATTGGAAGTGGTGCGTGAGGTTATGGCGCTACCGGCAGAATCTGAAGTGATGCCCGAATTAACCCCCGGTGGGGATGCC
GCCTTCATTTGTTCTTATCTGCAAGCGTTGGCGAAAGAAGATTGCGCAGCAGTGTTAGTGATTTCGCACTTGCCACTGGT
CGGGTATTTGGTCGCCGAGCTTTGCCCAGGGCAATGCCCTCCGATGTTTGCTACTTCAGCCATCGCCTGTATTGATCTCA
ATGGTAAGAGCGAAAAGGGTACGCTTGATTGGCAGGTGAGCCCTTCACAATTGTTGGCGAAGGCGTGTCATGGATAA

Upstream 100 bases:

>100_bases
TCTTTGCTTGCGGGCAAGGGTTTCGGCGGTACAGCACGCAAAGCGTTTCTGTATAGCGTTATTTGGTTAACAAAAACGGT
GCAATATGCAAGTTTTCATT

Downstream 100 bases:

>100_bases
GGCTCACCATGGGCTGTCATGACCAAGCCACCAGCCACTAAAATATAGCCTCCATCAACGTCTAACTGGCGCGGCATTCT
TGCCGCGCTTTCGCTTATTG

Product: phosphohistidine phosphatase

Products: NA

Alternate protein names: RX6 [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MRHGDAALDAASDAQRPLTLCGQDESRQIASWLSEQSVDIDQILVSPYLRARQTLEVVREVMALPAESEVMPELTPGGDA
AFICSYLQALAKEDCAAVLVISHLPLVGYLVAELCPGQCPPMFATSAIACIDLNGKSEKGTLDWQVSPSQLLAKACHG

Sequences:

>Translated_158_residues
MRHGDAALDAASDAQRPLTLCGQDESRQIASWLSEQSVDIDQILVSPYLRARQTLEVVREVMALPAESEVMPELTPGGDA
AFICSYLQALAKEDCAAVLVISHLPLVGYLVAELCPGQCPPMFATSAIACIDLNGKSEKGTLDWQVSPSQLLAKACHG
>Mature_158_residues
MRHGDAALDAASDAQRPLTLCGQDESRQIASWLSEQSVDIDQILVSPYLRARQTLEVVREVMALPAESEVMPELTPGGDA
AFICSYLQALAKEDCAAVLVISHLPLVGYLVAELCPGQCPPMFATSAIACIDLNGKSEKGTLDWQVSPSQLLAKACHG

Specific function: Exhibits phosphohistidine phosphatase activity towards the HPt domain of the ArcB sensor involved in the multistep His- Asp phosphorelay [H]

COG id: COG2062

COG function: function code T; Phosphohistidine phosphatase SixA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sixA phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788681, Length=156, Percent_Identity=63.4615384615385, Blast_Score=197, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR004449 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.- [C]

Molecular weight: Translated: 16880; Mature: 16880

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHGDAALDAASDAQRPLTLCGQDESRQIASWLSEQSVDIDQILVSPYLRARQTLEVVRE
CCCCCHHHCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VMALPAESEVMPELTPGGDAAFICSYLQALAKEDCAAVLVISHLPLVGYLVAELCPGQCP
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PMFATSAIACIDLNGKSEKGTLDWQVSPSQLLAKACHG
CCHHHCEEEEEECCCCCCCCEEEEEECHHHHHHHHHCC
>Mature Secondary Structure
MRHGDAALDAASDAQRPLTLCGQDESRQIASWLSEQSVDIDQILVSPYLRARQTLEVVRE
CCCCCHHHCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VMALPAESEVMPELTPGGDAAFICSYLQALAKEDCAAVLVISHLPLVGYLVAELCPGQCP
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PMFATSAIACIDLNGKSEKGTLDWQVSPSQLLAKACHG
CCHHHCEEEEEECCCCCCCCEEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9489669; 9205837; 9278503 [H]