Click here to switch to the map view.

The map label for this gene is cysW [H]

Identifier: 170023652

GI number: 170023652

Start: 1554352

End: 1555227

Strand: Direct

Name: cysW [H]

Synonym: YPK_1410

Alternate gene names: 170023652

Gene position: 1554352-1555227 (Clockwise)

Preceding gene: 170023651

Following gene: 170023653

Centisome position: 33.15

GC content: 53.2

Gene sequence:

>876_bases
ATGGTGGATGTTTCTGAATTTAACGGTGTTGCCCGCCCACCGATCAATTGGGGCAAATGGACGCTGATTGTCATTGGTGC
GGCGTTCTCGTTTTTGCTGCTGGTGATCCCGATGGTGTGGATCTTTATCACCGCGTTTTCTAAAGGCATTGCGGTGGTCG
GGCAGAATTTATTAAACCCAGATATGTTGCACGCCATCTGGCTGACGGTATTAGTGGCATTGATAACCGTGCCAGTGAAC
CTGGTTTTTGGGGTGGTGCTGGCTTGGCTGGTGACGCGCTTTGTTTTCCCCGGTCGCCAATTGTTGATGACGTTAATTGA
TATCCCGTTTGCGGTTTCGCCCGTCGTGGCGGGGCTGATGTATTTGTTGTTCTACGGCTCAAATGGGGTGGTCGGTGGCT
GGCTTGATGCCCACGATATCCAGTTGATGTTCTCCTGGCCCGGTATGGTGCTGGTCACCATTTTCGTCACCTGCCCTTTT
GTGGTGCGTGAACTGGTACCGGTGATGATGAGCCAAGGCAGTCAGGAAGATGAGGCTGCCGTATTACTCGGCGCTTCAGG
TTGGCAGATGTTCCGTCGGGTCACCTTACCCAATATTCGCTGGGCGTTGTTGTATGGCGTGGTGTTAACCAATGCCCGCG
CGATTGGTGAATTTGGTGCGGTCTCGGTGGTATCCGGTTCTATCCGTGGCGAGACGTATACCTTGCCACTGCAAGTTGAA
TTGCTGCATCAGGATTACAACACCGCCGGGGCATTTACTGCCGCCGCGTTACTGACTCTGATGGCAATAGTGACCCTTTT
TCTGAAGAGCGGCCTGCAATGGCGCTTGGCGCGTCAGGTTGTTCGTCTCGAACAGGAGCAAAAGCATGAGCATTGA

Upstream 100 bases:

>100_bases
CCAGCGCCATTGCCTCGGTGATTCTGGCCGTGTCACTGGCGCTGTTGTTTAGCATTAACACGTTACAAAGCCGCTTTGGT
CGGCGGATAGGTGGGCACTA

Downstream 100 bases:

>100_bases
AATTAATAATATCAGTAAGTATTTTGGCCGGACCAAGGTACTGAATGACATTACGCTTGATATTCCTTCAGGCCAAATGG
TGGCTCTGCTCGGCCCTTCT

Product: sulfate/thiosulfate transporter permease subunit

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MVDVSEFNGVARPPINWGKWTLIVIGAAFSFLLLVIPMVWIFITAFSKGIAVVGQNLLNPDMLHAIWLTVLVALITVPVN
LVFGVVLAWLVTRFVFPGRQLLMTLIDIPFAVSPVVAGLMYLLFYGSNGVVGGWLDAHDIQLMFSWPGMVLVTIFVTCPF
VVRELVPVMMSQGSQEDEAAVLLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETYTLPLQVE
LLHQDYNTAGAFTAAALLTLMAIVTLFLKSGLQWRLARQVVRLEQEQKHEH

Sequences:

>Translated_291_residues
MVDVSEFNGVARPPINWGKWTLIVIGAAFSFLLLVIPMVWIFITAFSKGIAVVGQNLLNPDMLHAIWLTVLVALITVPVN
LVFGVVLAWLVTRFVFPGRQLLMTLIDIPFAVSPVVAGLMYLLFYGSNGVVGGWLDAHDIQLMFSWPGMVLVTIFVTCPF
VVRELVPVMMSQGSQEDEAAVLLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETYTLPLQVE
LLHQDYNTAGAFTAAALLTLMAIVTLFLKSGLQWRLARQVVRLEQEQKHEH
>Mature_291_residues
MVDVSEFNGVARPPINWGKWTLIVIGAAFSFLLLVIPMVWIFITAFSKGIAVVGQNLLNPDMLHAIWLTVLVALITVPVN
LVFGVVLAWLVTRFVFPGRQLLMTLIDIPFAVSPVVAGLMYLLFYGSNGVVGGWLDAHDIQLMFSWPGMVLVTIFVTCPF
VVRELVPVMMSQGSQEDEAAVLLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETYTLPLQVE
LLHQDYNTAGAFTAAALLTLMAIVTLFLKSGLQWRLARQVVRLEQEQKHEH

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=291, Percent_Identity=78.0068728522337, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI1788764, Length=223, Percent_Identity=38.5650224215247, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1786980, Length=208, Percent_Identity=35.0961538461538, Blast_Score=95, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32109; Mature: 32109

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDVSEFNGVARPPINWGKWTLIVIGAAFSFLLLVIPMVWIFITAFSKGIAVVGQNLLNP
CCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DMLHAIWLTVLVALITVPVNLVFGVVLAWLVTRFVFPGRQLLMTLIDIPFAVSPVVAGLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHH
YLLFYGSNGVVGGWLDAHDIQLMFSWPGMVLVTIFVTCPFVVRELVPVMMSQGSQEDEAA
HHHHHCCCCCEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
VLLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETYTLPLQVE
EEEECHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCHHHEECCCCCCEEEEEEEEE
LLHQDYNTAGAFTAAALLTLMAIVTLFLKSGLQWRLARQVVRLEQEQKHEH
EHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVDVSEFNGVARPPINWGKWTLIVIGAAFSFLLLVIPMVWIFITAFSKGIAVVGQNLLNP
CCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DMLHAIWLTVLVALITVPVNLVFGVVLAWLVTRFVFPGRQLLMTLIDIPFAVSPVVAGLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHH
YLLFYGSNGVVGGWLDAHDIQLMFSWPGMVLVTIFVTCPFVVRELVPVMMSQGSQEDEAA
HHHHHCCCCCEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
VLLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETYTLPLQVE
EEEECHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCHHHEECCCCCCEEEEEEEEE
LLHQDYNTAGAFTAAALLTLMAIVTLFLKSGLQWRLARQVVRLEQEQKHEH
EHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]