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The map label for this gene is cysP [H]

Identifier: 170023650

GI number: 170023650

Start: 1552482

End: 1553519

Strand: Direct

Name: cysP [H]

Synonym: YPK_1408

Alternate gene names: 170023650

Gene position: 1552482-1553519 (Clockwise)

Preceding gene: 170023649

Following gene: 170023651

Centisome position: 33.11

GC content: 48.46

Gene sequence:

>1038_bases
ATGAAACAGAACTCAGTCAAAAAAAATGCGCGTAACGGATTGACCCACATTGCATTATTTAGTGCGCTGATACTCAGTGG
TGTCACTGCCTCAGCCACTGAGTTGCTCAATAGCTCTTATGATGTTTCCCGTGAATTATTCACGGCGCTGAATCCGGGTT
TTCAGGCACAGTGGGAACAGCAGAACCCCGGTGACAAACTGACTATCAAACAATCCCATGCGGGTTCTTCCAAGCAGGCA
TTGGCTATCTTACAAGGCCTGAAAGCCGATGTGGTCACCTACAACCAGATTACTGATGTGCAAATCCTTCATGACCGTGG
CAATTTGATCCCCGCCGATTGGCAAGCCCGTTTGCCGAATAACAGCTCACCGTTCTACTCCACCATGGCGTTCCTGGTCC
GCAAAGGCAATCCAAAAAATATCCGCAATTGGGATGATTTGGTCCGCGAAGACGTCAAGCTGGTTTTCCCTAATCCTAAA
ACCTCCGGTAATGGCCGCTATACCTATCTGGCTGCTTGGGGAGCGACCCAACTGGCCGATGGCGGCGATGAGGCGAAAAC
CCGCGACTGGATGAAACGCTTTTTGAAAAATGTTGAAGTGTTTGATACCGGTGGCCGTGGGGCAACCACGACATTCGTTG
AACGTGGCTTGGGTGATGTACTGATCAGTTTCGAATCGGAAGTTAACAATATTCGCAAAGAGTACGGCAGTGACCAATAC
GAAGTTATTGTCCCGCCAGTGGATATTTTGGCTGAGTTCCCGGTTGCCTGGGTGGATAAAAATGTAGAAAAGAATGGCAC
TGAAAAAGCGGCCAAAGCTTATCTCAATTATCTCTATAGCCCGCCAGCACAGCAGGTGATCACTCGCTTCAATTACCGTG
TTTACGATAAAGCGGCAATGGAGGCGGCGAAATCTCAATTCCCAGACACCAAATTATTCCGAGTTGAAGATCAATTCGGT
AGCTGGCCACAGGTGATGAGTACCCATTTTACTACTGGCGGCGTACTGGATAAATTGTTAGCAGAAGGGCATCAGTAA

Upstream 100 bases:

>100_bases
GGTATACGCCTAGTTATAAATACACTGAACATAATTTAAAGGCACACCGTTCATAATGAATGACATGCCTATTGGTTGAA
CTCAGTGGACAAGGTGCGGA

Downstream 100 bases:

>100_bases
TGTTGTCGGCATCCAGTAAACGGGTTTTGCCCGGATTTACCCTCAGTCTTGGGAGTAGCCTGCTTTATACCTGCTTGATT
TTGCTATTACCGCTTAGCGC

Product: thiosulfate transporter subunit

Products: SO42- [Cytoplasm]; phosphate; ADP; S2O32- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKQNSVKKNARNGLTHIALFSALILSGVTASATELLNSSYDVSRELFTALNPGFQAQWEQQNPGDKLTIKQSHAGSSKQA
LAILQGLKADVVTYNQITDVQILHDRGNLIPADWQARLPNNSSPFYSTMAFLVRKGNPKNIRNWDDLVREDVKLVFPNPK
TSGNGRYTYLAAWGATQLADGGDEAKTRDWMKRFLKNVEVFDTGGRGATTTFVERGLGDVLISFESEVNNIRKEYGSDQY
EVIVPPVDILAEFPVAWVDKNVEKNGTEKAAKAYLNYLYSPPAQQVITRFNYRVYDKAAMEAAKSQFPDTKLFRVEDQFG
SWPQVMSTHFTTGGVLDKLLAEGHQ

Sequences:

>Translated_345_residues
MKQNSVKKNARNGLTHIALFSALILSGVTASATELLNSSYDVSRELFTALNPGFQAQWEQQNPGDKLTIKQSHAGSSKQA
LAILQGLKADVVTYNQITDVQILHDRGNLIPADWQARLPNNSSPFYSTMAFLVRKGNPKNIRNWDDLVREDVKLVFPNPK
TSGNGRYTYLAAWGATQLADGGDEAKTRDWMKRFLKNVEVFDTGGRGATTTFVERGLGDVLISFESEVNNIRKEYGSDQY
EVIVPPVDILAEFPVAWVDKNVEKNGTEKAAKAYLNYLYSPPAQQVITRFNYRVYDKAAMEAAKSQFPDTKLFRVEDQFG
SWPQVMSTHFTTGGVLDKLLAEGHQ
>Mature_345_residues
MKQNSVKKNARNGLTHIALFSALILSGVTASATELLNSSYDVSRELFTALNPGFQAQWEQQNPGDKLTIKQSHAGSSKQA
LAILQGLKADVVTYNQITDVQILHDRGNLIPADWQARLPNNSSPFYSTMAFLVRKGNPKNIRNWDDLVREDVKLVFPNPK
TSGNGRYTYLAAWGATQLADGGDEAKTRDWMKRFLKNVEVFDTGGRGATTTFVERGLGDVLISFESEVNNIRKEYGSDQY
EVIVPPVDILAEFPVAWVDKNVEKNGTEKAAKAYLNYLYSPPAQQVITRFNYRVYDKAAMEAAKSQFPDTKLFRVEDQFG
SWPQVMSTHFTTGGVLDKLLAEGHQ

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport [H]

COG id: COG4150

COG function: function code P; ABC-type sulfate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic sulfate-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1788765, Length=313, Percent_Identity=77.9552715654952, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1790351, Length=323, Percent_Identity=45.8204334365325, Blast_Score=303, Evalue=8e-84,

Paralogues:

None

Copy number: 440 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059
- InterPro:   IPR000957
- InterPro:   IPR005669 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 38506; Mature: 38506

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQNSVKKNARNGLTHIALFSALILSGVTASATELLNSSYDVSRELFTALNPGFQAQWEQ
CCCCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
QNPGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQITDVQILHDRGNLIPADWQARLPN
CCCCCEEEEECCCCCCHHHHHHHHHCCHHCEEEECCCCCEEEEECCCCCCCCCCCCCCCC
NSSPFYSTMAFLVRKGNPKNIRNWDDLVREDVKLVFPNPKTSGNGRYTYLAAWGATQLAD
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEECCCCCCCCCCCEEEEEECCCHHHCC
GGDEAKTRDWMKRFLKNVEVFDTGGRGATTTFVERGLGDVLISFESEVNNIRKEYGSDQY
CCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCHHHEEEHHHHHHHHHHHHHCCCCE
EVIVPPVDILAEFPVAWVDKNVEKNGTEKAAKAYLNYLYSPPAQQVITRFNYRVYDKAAM
EEEECCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
EAAKSQFPDTKLFRVEDQFGSWPQVMSTHFTTGGVLDKLLAEGHQ
HHHHHHCCCCEEEEECHHHCCCHHHHHHHCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKQNSVKKNARNGLTHIALFSALILSGVTASATELLNSSYDVSRELFTALNPGFQAQWEQ
CCCCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
QNPGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQITDVQILHDRGNLIPADWQARLPN
CCCCCEEEEECCCCCCHHHHHHHHHCCHHCEEEECCCCCEEEEECCCCCCCCCCCCCCCC
NSSPFYSTMAFLVRKGNPKNIRNWDDLVREDVKLVFPNPKTSGNGRYTYLAAWGATQLAD
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEECCCCCCCCCCCEEEEEECCCHHHCC
GGDEAKTRDWMKRFLKNVEVFDTGGRGATTTFVERGLGDVLISFESEVNNIRKEYGSDQY
CCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCHHHEEEHHHHHHHHHHHHHCCCCE
EVIVPPVDILAEFPVAWVDKNVEKNGTEKAAKAYLNYLYSPPAQQVITRFNYRVYDKAAM
EEEECCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
EAAKSQFPDTKLFRVEDQFGSWPQVMSTHFTTGGVLDKLLAEGHQ
HHHHHHCCCCEEEEECHHHCCCHHHHHHHCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: SO42- [Periplasm]; H2O; ATP; S2O32- [Periplasm] [C]

Specific reaction: SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2188959; 9205837; 9278503; 9298646 [H]