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The map label for this gene is mocR [H]

Identifier: 170023576

GI number: 170023576

Start: 1469959

End: 1471464

Strand: Reverse

Name: mocR [H]

Synonym: YPK_1334

Alternate gene names: 170023576

Gene position: 1471464-1469959 (Counterclockwise)

Preceding gene: 170023582

Following gene: 170023575

Centisome position: 31.38

GC content: 54.52

Gene sequence:

>1506_bases
TTGCGATCACTGCTTTCTGACCTGCTGTTACAGCGCCTGACACCGGCTACCCTCTCTACGGTTCCAGTGGCTAAAAATAA
GCGGCTCTACCGTGCGCTGCGTTTATCTATTCTGGACGGCAGCATCCGTGCCGGTAGCCGCTTACCGGCCTCACGTGATC
TGGCACAAGAACTGGAGATTTCGCGCAATACGGTGCTGGCCGCCTATGACCAATTACAGGCAGAAGGCTATATTCAGACA
CGTACCGGCGGCGGTACCTTTGTGACCACTGATTTGCCAGAAGACGGGCTGAACAAAATGGATACCCTGCCCCAGCATAG
TGGGCCAGAACCTGATGTGGCCCTGTCTACACGCGCTACCCACCTGCTGAACCACTGCGGCGTGGCGTCCTATCAATGGG
GCACCTTCATGCCCGGCGTGCCAGATGTCAGGTTATTTCCCCATGAGGTGTGGCGTAAATTACAAACGCGTCTCAGCCGC
CATTTGAATCCAGAAAATCTGACTTATTCTGTTCATGGCGGTTGTCCGCAATTGCAGCAAGCGTTGGCCGACTATCTGCG
AATTGCCCGTTCCGTTTCCTGTACTCCGGATCAGATTTTGATCACTGCGGGCACGCATCAGGCACTGGATTTGTTGGCAA
AAATGTTGTGCGACCCGGGCGATCACGCCTGGATTGAAGAACCCAGCTACTGGGGGATCCGCAACGTGTTAACCATCAAT
GGCATAGAGGTCATCCCCGTGTCAGTGGACGAAAATGGTATGGATCCACTGGATTTGCCGTTTGAATCACGCTCGCCACG
TCTTATTTGCGTGACGCCATCCCATCAATATCCGTTAGGCTCGGTGATGAGCCTGACACGACGTCAGCGTATTTTGGCGT
TGGCGCAGCAGCATAACTGCTGGGTGGTGGAAGATGATTACGACAGCGAGTTCCGTTTTTCAGGCAGTCCGATCCCCGCG
CTGCAAGGGCTGATCCCCGATGCGCCCGTCATTTATCTCGGTACCTTCAGTAAAACCCTGTATCCAGGGATGCGTATCAG
CTACATGGTACTGCCACGCCCACTGGCGCAGCAGTTCAAGGTGGCACATTCCGAGTTATACCGTGGAGGAAATGGGATGA
TGCAACTGACGCTGGCAGAATTTATCCGCGAAGGCCACTATGCCTCCCATATCCGTCGTATGCGGTTGATATATGGCAAG
CGCCGGACCGCACTGGTTGCCATGATCAAACAACAGCTTGGGGGGTCATTTCTCGCGGAATACGGTAACGCGGGGCTGCA
CCTGATTCTGGCTTTACCGGAGTCTATTGATGACGTGGCGTTAAGCGCTGAACTGGAGCAGAAAGGGGTACTCGTCCGTG
CGCTCTCTGGCTATTACTTAAAAAGTCCCCCGCGACGAGGGCTGTTACTCGGTTATGGTTGCGTACCAGAGGAGGCGATG
GAAGCCGTATTCGCACCGATAGTCAGCTATCTCAGACGGCGGATAAAACCCGATGACGCGATCTGA

Upstream 100 bases:

>100_bases
TTCGTCGATTAATTTGTATATTAATTAACCTAGTCTCGGTTTTTTATCCCTAAGTCGCCCTACAATCCAGTGCCAATTTT
GATTATTTTAAGGTGCCAAT

Downstream 100 bases:

>100_bases
AACGGACAGTTTATCAATCACCGCCTATCGATTTCACTGCATTAATTAAACTGCGTCACCACCTTGACCAAGCTTGCCTA
TTTCTGTCTAAACCCTCACT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MRSLLSDLLLQRLTPATLSTVPVAKNKRLYRALRLSILDGSIRAGSRLPASRDLAQELEISRNTVLAAYDQLQAEGYIQT
RTGGGTFVTTDLPEDGLNKMDTLPQHSGPEPDVALSTRATHLLNHCGVASYQWGTFMPGVPDVRLFPHEVWRKLQTRLSR
HLNPENLTYSVHGGCPQLQQALADYLRIARSVSCTPDQILITAGTHQALDLLAKMLCDPGDHAWIEEPSYWGIRNVLTIN
GIEVIPVSVDENGMDPLDLPFESRSPRLICVTPSHQYPLGSVMSLTRRQRILALAQQHNCWVVEDDYDSEFRFSGSPIPA
LQGLIPDAPVIYLGTFSKTLYPGMRISYMVLPRPLAQQFKVAHSELYRGGNGMMQLTLAEFIREGHYASHIRRMRLIYGK
RRTALVAMIKQQLGGSFLAEYGNAGLHLILALPESIDDVALSAELEQKGVLVRALSGYYLKSPPRRGLLLGYGCVPEEAM
EAVFAPIVSYLRRRIKPDDAI

Sequences:

>Translated_501_residues
MRSLLSDLLLQRLTPATLSTVPVAKNKRLYRALRLSILDGSIRAGSRLPASRDLAQELEISRNTVLAAYDQLQAEGYIQT
RTGGGTFVTTDLPEDGLNKMDTLPQHSGPEPDVALSTRATHLLNHCGVASYQWGTFMPGVPDVRLFPHEVWRKLQTRLSR
HLNPENLTYSVHGGCPQLQQALADYLRIARSVSCTPDQILITAGTHQALDLLAKMLCDPGDHAWIEEPSYWGIRNVLTIN
GIEVIPVSVDENGMDPLDLPFESRSPRLICVTPSHQYPLGSVMSLTRRQRILALAQQHNCWVVEDDYDSEFRFSGSPIPA
LQGLIPDAPVIYLGTFSKTLYPGMRISYMVLPRPLAQQFKVAHSELYRGGNGMMQLTLAEFIREGHYASHIRRMRLIYGK
RRTALVAMIKQQLGGSFLAEYGNAGLHLILALPESIDDVALSAELEQKGVLVRALSGYYLKSPPRRGLLLGYGCVPEEAM
EAVFAPIVSYLRRRIKPDDAI
>Mature_501_residues
MRSLLSDLLLQRLTPATLSTVPVAKNKRLYRALRLSILDGSIRAGSRLPASRDLAQELEISRNTVLAAYDQLQAEGYIQT
RTGGGTFVTTDLPEDGLNKMDTLPQHSGPEPDVALSTRATHLLNHCGVASYQWGTFMPGVPDVRLFPHEVWRKLQTRLSR
HLNPENLTYSVHGGCPQLQQALADYLRIARSVSCTPDQILITAGTHQALDLLAKMLCDPGDHAWIEEPSYWGIRNVLTIN
GIEVIPVSVDENGMDPLDLPFESRSPRLICVTPSHQYPLGSVMSLTRRQRILALAQQHNCWVVEDDYDSEFRFSGSPIPA
LQGLIPDAPVIYLGTFSKTLYPGMRISYMVLPRPLAQQFKVAHSELYRGGNGMMQLTLAEFIREGHYASHIRRMRLIYGK
RRTALVAMIKQQLGGSFLAEYGNAGLHLILALPESIDDVALSAELEQKGVLVRALSGYYLKSPPRRGLLLGYGCVPEEAM
EAVFAPIVSYLRRRIKPDDAI

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=393, Percent_Identity=24.1730279898219, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI33469970, Length=393, Percent_Identity=24.1730279898219, Blast_Score=107, Evalue=3e-23,
Organism=Escherichia coli, GI1790797, Length=427, Percent_Identity=28.3372365339578, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1787710, Length=424, Percent_Identity=26.8867924528302, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55728; Mature: 55728

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLLSDLLLQRLTPATLSTVPVAKNKRLYRALRLSILDGSIRAGSRLPASRDLAQELEI
CHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
SRNTVLAAYDQLQAEGYIQTRTGGGTFVTTDLPEDGLNKMDTLPQHSGPEPDVALSTRAT
CCCHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCHHHHCCCCCCCCCCCEEEHHHHH
HLLNHCGVASYQWGTFMPGVPDVRLFPHEVWRKLQTRLSRHLNPENLTYSVHGGCPQLQQ
HHHHHCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
ALADYLRIARSVSCTPDQILITAGTHQALDLLAKMLCDPGDHAWIEEPSYWGIRNVLTIN
HHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEC
GIEVIPVSVDENGMDPLDLPFESRSPRLICVTPSHQYPLGSVMSLTRRQRILALAQQHNC
CEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
WVVEDDYDSEFRFSGSPIPALQGLIPDAPVIYLGTFSKTLYPGMRISYMVLPRPLAQQFK
EEEECCCCCCEEECCCCCHHHHCCCCCCCEEEEECCHHHHCCCCEEEEEECCCHHHHHHH
VAHSELYRGGNGMMQLTLAEFIREGHYASHIRRMRLIYGKRRTALVAMIKQQLGGSFLAE
HHHHHHHCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
YGNAGLHLILALPESIDDVALSAELEQKGVLVRALSGYYLKSPPRRGLLLGYGCVPEEAM
HCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEEECCCCCHHHH
EAVFAPIVSYLRRRIKPDDAI
HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRSLLSDLLLQRLTPATLSTVPVAKNKRLYRALRLSILDGSIRAGSRLPASRDLAQELEI
CHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
SRNTVLAAYDQLQAEGYIQTRTGGGTFVTTDLPEDGLNKMDTLPQHSGPEPDVALSTRAT
CCCHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCHHHHCCCCCCCCCCCEEEHHHHH
HLLNHCGVASYQWGTFMPGVPDVRLFPHEVWRKLQTRLSRHLNPENLTYSVHGGCPQLQQ
HHHHHCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
ALADYLRIARSVSCTPDQILITAGTHQALDLLAKMLCDPGDHAWIEEPSYWGIRNVLTIN
HHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEC
GIEVIPVSVDENGMDPLDLPFESRSPRLICVTPSHQYPLGSVMSLTRRQRILALAQQHNC
CEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
WVVEDDYDSEFRFSGSPIPALQGLIPDAPVIYLGTFSKTLYPGMRISYMVLPRPLAQQFK
EEEECCCCCCEEECCCCCHHHHCCCCCCCEEEEECCHHHHCCCCEEEEEECCCHHHHHHH
VAHSELYRGGNGMMQLTLAEFIREGHYASHIRRMRLIYGKRRTALVAMIKQQLGGSFLAE
HHHHHHHCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
YGNAGLHLILALPESIDDVALSAELEQKGVLVRALSGYYLKSPPRRGLLLGYGCVPEEAM
HCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEEECCCCCHHHH
EAVFAPIVSYLRRRIKPDDAI
HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]